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Lotilaner
go.drugbank.com/drugs/DB17992ApprovedInvestigationalVet approved[A260741] On July 25, 2023, lotilaner was approved by the FDA for the treatment of Demodex blepharitis, making it the first and only approved therapeutic for this condition.[L47551] … [L47546] Lotilaner has largely been used for veterinary uses as an antiparasitic agent to treat flea and tick infestations in animals.
Categories: Heterocyclic Compounds, 1-Ring, Scabicides, Insecticides and RepellentsSynonyms: 2-thiophenecarboxamide, 5-((5s)-4,5-dihydro-5-(3,4,5-trichlorophenyl)-5-(trifluoromethyl)-3-isoxazolyl)-3-methyl-n-(2-oxo-2-((2,2,2-trifluoroethyl)amino)ethyl)-, 3-methyi-n-(2-oxo-2-((2,2,2-trifluoroethyl)amino)ethyl)-5-((55)-5-(3,4,5-trichlorophenyl)-5-(trifluoromethyl)-4,5-dihydro-1,2-oxazol-3-yl)thiophene-2-carboxamide5-Nitroindazole
go.drugbank.com/drugs/DB04534ExperimentalSynonyms: 5-Nitro-1H-indazole, 5-NitroindazoleCategories: Heterocyclic Compounds, 1-Ring, Heterocyclic Compounds, 2-Ring5-methylbenzimidazole
go.drugbank.com/drugs/DB03177ExperimentalSynonyms: 5-methyl-1H-benzimidazole, 6-methyl-1H-benzimidazoleCategories: Heterocyclic Compounds, 2-Ring5-Iodouracil
go.drugbank.com/drugs/DB03554ExperimentalSynonyms: 5-IodouracilCategories: Heterocyclic Compounds, 1-Ring5-Bromoindirubin
go.drugbank.com/drugs/DB07493ExperimentalSynonyms: (2Z)-5'-bromo-2,3'-biindole-2',3(1H,1'H)-dione ammoniate, 5-BromoindirubinMetacycline
go.drugbank.com/drugs/DB00931ApprovedA broad-spectrum semisynthetic antibiotic related to tetracycline but excreted more slowly and maintaining effective blood levels for a more extended period.
Synonyms: 6-Methylene-5-oxytetracycline, 6-Methylene-5-hydroxytetracyclineNitrofural
go.drugbank.com/drugs/DB00336ApprovedVet approvedWithdrawnNitrofural or nitrofurazone is a topical anti-infective agent effective against gram-negative and gram-positive bacteria. It is used for superficial wounds, burns, ulcers, and skin infections.
Mixtures: MADECASSOL CCategories: Heterocyclic Compounds, 1-Ring, Antiseptics and DisinfectantsMethyl aminolevulinate
go.drugbank.com/drugs/DB00992ApprovedInvestigationalMethyl aminolevulinate is a prodrug that is metabolised to Protoporphyrin IX (a photosensitizer) used in photodynamic therapy.
Synonyms: methyl 5-aminolevulinate, 5-aminolevulinic acid methyl esterCategories: Amino Acids, Peptides, and Proteins, Skin and Mucous Membrane Agents5'-S-methyl-5'-thioadenosine
go.drugbank.com/drugs/DB02282InvestigationalCategories: Heterocyclic Compounds, 2-Ring, Amino Acids, Peptides, and ProteinsSynonyms: 5'-S-methyl-5'-thioadenosine, 5'-Deoxy-5'-(methylthio)adenosine