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Balaglitazone
go.drugbank.com/drugs/DB12781InvestigationalBalaglitazone has been used in trials studying the treatment of Diabetes Mellitus, Type 2.
Categories: Cytochrome P-450 CYP2C8 Inhibitors, Cytochrome P-450 Substratesp-Quaterphenyl
go.drugbank.com/drugs/DB12794Investigationalp-Quaterphenyl has been used in trials studying the treatment of Malaria.
Laniquidar
go.drugbank.com/drugs/DB12799InvestigationalLaniquidar has been used in trials studying the treatment of Breast Cancer.
Categories: P-glycoprotein inhibitorsTrifarotene
go.drugbank.com/drugs/DB12808ApprovedInvestigationalTrifarotene is a topical retinoid cream used in the treatment of acne vulgaris that was first approved for use in the United States in October 2019. Retinoids are a class of medications structurally and functionally analogous to vitamin ...
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP2B6 SubstratesCepeginterferon alfa-2B
go.drugbank.com/drugs/DB12814InvestigationalCepeginterferon alfa-2B is under investigation in clinical trial NCT01889433 (An Open-label Comparative Efficacy and Safety Study of Algeron (Cepeginterferon Alfa-2b) in Treatment-naive Patients With Chronic Hepatitis C).
Categories: Cytochrome P-450 CYP1A2 Inhibitors, Cytochrome P-450 Enzyme InhibitorsTerpinen-4-ol
go.drugbank.com/drugs/DB12816InvestigationalTerpinen-4-ol is under investigation in clinical trial NCT01647217 (Demodex Blepharitis Treatment Study).
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP2A6 SubstratesTandospirone
go.drugbank.com/drugs/DB12833InvestigationalTandospirone has been used in trials studying the treatment of Schizophrenia.
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP2D6 SubstratesDihydralazine
go.drugbank.com/drugs/DB12945ApprovedWithdrawnDihydralazine is under investigation in clinical trial NCT00311974 (The Effect of Dihydralazine on Kidney Function and Hormones in Healthy Individuals).
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP1A2 InhibitorsPexidartinib
go.drugbank.com/drugs/DB12978ApprovedInvestigationalPexidartinib is a selective tyrosine kinase inhibitor that works by inhibiting the colony-stimulating factor (CSF1)/CSF1 receptor pathway. Pexidartinib was originally developed by Daiichi Sankyo, Inc. and it was approved by the FDA in Au...
Categories: Cytochrome P-450 CYP2B6 Inducers, Cytochrome P-450 SubstratesNepicastat
go.drugbank.com/drugs/DB12979InvestigationalNepicastat has been investigated for the treatment of Cocaine Dependence and Posttraumatic Stress Disorder.
Categories: P-glycoprotein substrates