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Displaying results 2211 - 2220 of 7063 in total
  1. Drug

    Vepdegestrant

    go.drugbank.com/drugs/DB19006
    ApprovedInvestigational

    [A275507, A275508, A275511] It was identified through a targeted medicinal chemistry optimization campaign to act as a next-generation endocrine therapy for breast cancer. … fulvestrant], which has historically been a standard of care for these advanced breast cancers.

  2. Drug

    Capecitabine

    go.drugbank.com/drugs/DB01101
    ApprovedInvestigational

    Capecitabine is a prodrug, that is enzymatically converted to fluorouracil (antimetabolite) in the tumor, where it inhibits DNA synthesis and slows growth of tumor tissue.

    Categories: Cytochrome P-450 CYP2C9 Substrates with a Narrow Therapeutic IndexSynonyms: pentyl 1-(5-deoxy-β-D-ribofuranosyl)-5-fluoro-1,2-dihydro-2-oxo-4-pyrimidinecarbamate, Pentyl [1-(5-deoxy-β-D-ribofuranosyl)-5-fluoro-2-oxo-1,2-dihydropyrimidin-4-yl]carbamate
  3. Drug

    Sotorasib

    go.drugbank.com/drugs/DB15569
    ApprovedInvestigational

    [A187547] Sotorasib was granted FDA approval on May 28, 2021,[L34288] followed by the European Commission's approval on January 6, 2022.[L56070] … [A187550] Mutant KRAS discovered in 1982 but was not considered a druggable target until the mid-2010s.[A235168] It is the first experimental KRAS inhibitor.

    Synonyms: 6-fluoro-7-(2-fluoro-6-hydroxyphenyl)-(1M)-1-[4-methyl-2-(propan-2-yl)pyridin-3-yl]-4-[(2S)-2- methyl-4-(prop-2-enoyl)piperazin-1-yl]pyrido[2,3-d]pyrimidin-2(1H)-one
  4. Drug

    Phenarsone sulfoxylate

    go.drugbank.com/drugs/DB21104
    Experimental

    Phenarsone sulfoxylate is a small molecule drug. Phenarsone sulfoxylate has a monoisotopic molecular weight of 310.94 Da.

  5. Drug

    Dimecrotic acid

    go.drugbank.com/drugs/DB21126
    Experimental

    Dimecrotic acid is a small molecule drug. Dimecrotic acid has a monoisotopic molecular weight of 222.09 Da.

  6. Drug

    Bimatoprost grenod

    go.drugbank.com/drugs/DB21634
    Experimental

    Bimatoprost grenod is a small molecule drug. Bimatoprost grenod has a monoisotopic molecular weight of 574.33 Da.

  7. Drug

    Metiazinic acid

    go.drugbank.com/drugs/DB19572
    Experimental

    Metiazinic acid is a small molecule drug. Metiazinic acid has a monoisotopic molecular weight of 271.07 Da.

  8. Drug

    Nixylic acid

    go.drugbank.com/drugs/DB19661
    Experimental

    Nixylic acid is a small molecule drug. Nixylic acid has a monoisotopic molecular weight of 242.11 Da.

  9. Drug

    Flavodic acid

    go.drugbank.com/drugs/DB19758
    Experimental

    Flavodic acid is a small molecule drug. Flavodic acid has a monoisotopic molecular weight of 370.07 Da.

  10. Drug

    Diprogulic acid

    go.drugbank.com/drugs/DB19811
    Experimental

    Diprogulic acid is a small molecule drug. Diprogulic acid has a monoisotopic molecular weight of 274.11 Da.