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Displaying results 2221 - 2230 of 8171 in total
  1. Drug

    Silodosin

    go.drugbank.com/drugs/DB06207
    ApprovedInvestigational

    Silodosin is a selective antagonist of alpha(α)-1 adrenergic receptors that binds to the α1A subtype with the highest affinity. α1-adrenergic receptors regulate smooth muscle tone in the bladder neck, prostate, and prostatic urethra: the...

    Categories: Cytochrome P-450 Substrates, P-glycoprotein substrates
  2. Drug

    Risdiplam

    go.drugbank.com/drugs/DB15305
    ApprovedInvestigational

    Risdiplam is an orally bioavailable mRNA splicing modifier used for the treatment of spinal muscular atrophy (SMA).

    Categories: Cytochrome P-450 Substrates, P-glycoprotein substrates
  3. Drug

    Drotaverine

    go.drugbank.com/drugs/DB06751
    ApprovedWithdrawn

    Drotaverine is an antispasmodic drug that works by inhibiting phosphodiesterase-4 (PDE4).

  4. Drug

    Bopindolol

    go.drugbank.com/drugs/DB08807
    Experimental

    Bopindolol (INN) is an ester prodrug for the beta blocker [pindolol].

    Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP2D6 Substrates
  5. Drug

    Filgrastim

    go.drugbank.com/drugs/DB00099
    ApprovedInvestigational

    It has an amino acid sequence identical to endogenous G-CSF, but it is non-glycosylated unlike the endogenous G-CSF and has an N-terminal methionine added in the sequence for expression in _E. Coli_.

    Products: ZARZIO (30 MU), NEUPOGEN (30 MU)
  6. Drug

    Milrinone

    go.drugbank.com/drugs/DB00235
    ApprovedInvestigational

    Often the result of long-term myocardial ischemia, cardiomyopathy, or other cardiac insults, heart failure results from an inability of the heart to perfuse peripheral tissues with sufficient oxygen and

    Products: AUMECONT P
  7. Drug

    Chaetomium globosum

    go.drugbank.com/drugs/DB10430
    Approved

    Chaetomium globosum is a fungus which can provoke allergic reactions. Chaetomium globosum extract is used in allergenic testing.

  8. Drug

    Cladosporium sphaerospermum

    go.drugbank.com/drugs/DB10432
    Approved

    Cladosporium sphaerospermum is a fungus which can provoke allergic reactions. Cladosporium sphaerospermum extract is used in allergenic testing.

  9. Drug

    Ustilago tritici

    go.drugbank.com/drugs/DB10444
    Approved

    Ustilago tritici is a fungus which can provoke allergic reactions. Ustilago tritici extract is used in allergenic testing.

  10. Drug

    Trichophyton mentagrophytes

    go.drugbank.com/drugs/DB10446
    Approved

    Trichophyton mentagrophytes is a fungus which can provoke allergic reactions. Trichophyton mentagrophytes extract is used in allergenic testing.