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V-SARS
go.drugbank.com/drugs/DB15812InvestigationalThis therapeutic concept was applied to the development of V-SARS, which heat inactivates the plasma, and packages it into a once-daily pill form.
PF-03758309
go.drugbank.com/drugs/DB11775InvestigationalPF-03758309 has been used in trials studying the treatment of Advanced Solid Tumors.
Salts: Pf 03758309 HydrochlorideLoxapine
go.drugbank.com/drugs/DB00408ApprovedInvestigationalAn antipsychotic agent used in schizophrenia. [PubChem]
Categories: P-glycoprotein inhibitors, Dopamine D2 Receptor AntagonistsPF-477736
go.drugbank.com/drugs/DB12611InvestigationalPF-00477736 has been used in trials studying the treatment of Neoplasms.
PF-04217903
go.drugbank.com/drugs/DB12848InvestigationalPF-04217903 has been used in trials studying the treatment of Neoplasms.
Imidacloprid
go.drugbank.com/drugs/DB11421ExperimentalVet approvedIt is marketed as pest control, seed treatment, an insecticide spray, termite control, flea control, and a systemic insecticide. … Imidacloprid is a patented chemical, Imidacloprid is manufactured by Bayer Cropscience (part of Bayer AG) and sold under trade names Kohinor, Admire, Advantage, Gaucho, Merit, Confidor, Hachikusan, Premise
Thrombin alfa
go.drugbank.com/drugs/DB11572ApprovedThrombin Alfa is a human coagulation protein produced via recombinant DNA technology from a genetically modified CHO cell line. Thrombin Alfa is identical in amino acid sequence and structurally similar to naturally occurring human throm...
Oliceridine
go.drugbank.com/drugs/DB14881ApprovedInvestigational[A218026, A218031, A218051, A218056, A218061, A218066, A218071, L15516] Oliceridine was first reported in 2013,[A218026, A218086] but was initially not approved by the FDA due to concerns raised by … [A218031, A218046] However, due to the ability of some opioid agonists to bind to other targets, as well as activation of additional downstream pathways from opioid receptors such as those involving β-arrestin
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP2C9 SubstratesIsosorbide
go.drugbank.com/drugs/DB09401ApprovedInvestigationalIsosorbide was previously available in an oral formulation for the reduction of intraocular pressure. It was approved by the FDA in 1980, but has since been discontinued. … Currently, isosorbide is an organic nitrate currently available in the [isosorbide mononitrate] and [isosorbide dinitrate] forms, and is used for the prevention of angina.
Betamethasone phosphate
go.drugbank.com/drugs/DB14669ApprovedVet approvedBetamethasone phosphate is a prodrug that is rapidly hydrolyzed, providing rapidly accessible betamethasone to agonize glucocorticoid receptors. Betamethasone provides greater anti-inflammatory activity than prednisolone with less sodium...
Categories: P-glycoprotein inducers, Cytochrome P-450 CYP3A Inducers