PF-03758309

DB11775InvestigationalSmall molecule

PF-03758309 has been used in trials studying the treatment of Advanced Solid Tumors.

Chemical structure of PF-03758309
Mechanism
Curator reviewed
Formula / weight
C25H30N8OS · 490.63 g/mol (avg)
Code names
PF-3758309

Resolves to

Compound
UNIIPK459EA5I2CAS898044-15-0ChEMBLCHEMBL3128043ChEBI93751PubChem25227462
Structure
InChIKeyAYCPARAPKDAOEN-LJQANCHMSA-NSMILESCN(C)C[C@@H](NC(=O)N1CC2=C(NN=C2NC2=C3SC=CC3=NC(C)=N2)C1(C)C)C1=CC=CC=C1
Targets
O96013PAK4

What you can answer from here — as of August 30, 2026

1Protein targetEach mapped to UniProt, with action and pharmacological action
Listed above
1Clinical trialPhase, status and sponsor resolved per trial
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6+ReferencesStructured and connected to the statements they support
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Which drugs share a target with PF-03758309, and which of those have an active Phase 3 trial?

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