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Displaying results 2221 - 2230 of 3730 in total
  1. Drug

    Naxifylline

    go.drugbank.com/drugs/DB06471
    Experimental

    Categories: Purinergic P1 Receptor Antagonists, Adenosine A1 Receptor Antagonists
  2. Drug

    Namodenoson

    go.drugbank.com/drugs/DB12885
    Investigational

    Namodenoson has been used in trials studying the treatment of Chronic Hepatitis C and Hepatocellular Carcinoma.

    Categories: Purinergic P1 Receptor Agonists
  3. Drug

    DPCPX

    go.drugbank.com/drugs/DB12946
    Investigational

    CPX has been used in trials studying the treatment of Cystic Fibrosis.

    Categories: Purinergic P1 Receptor Antagonists, Adenosine A1 Receptor Antagonists
  4. Drug

    Binodenoson

    go.drugbank.com/drugs/DB04853
    Investigational

    Binodenoson is a pharmacologic stress agent specific to the only adenosine receptor necessary for increased cardiac blood flow, the A<sub>2A</sub> receptor.

    Categories: Purinergic P1 Receptor Agonists
  5. Drug

    Istradefylline

    go.drugbank.com/drugs/DB11757
    ApprovedInvestigational

    Istradefylline, or KW6002, was developed by Kyowa Hakko Kirin in Japan for the treatment of Parkinson's disease as an adjunct to standard therapy. Unlike standard dopaminergic therapies for Parkinson's, Istradefylline targets adenosine A...

    Categories: Purinergic P1 Receptor Antagonists, Adenosine A2 Receptor Antagonists
  6. Drug

    Regrelor

    go.drugbank.com/drugs/DB05553
    Investigational

    Categories: Purinergic P2 Receptor Antagonists
  7. Drug

    Tecadenoson

    go.drugbank.com/drugs/DB04954
    Investigational

    Tecadenoson is a novel selective A1 adenosine receptor agonist that is currently being evaluated for the conversion of paroxysmal supraventricular tachycardia (PSVT) to sinus rhythm.

    Categories: Purinergic P1 Receptor Agonists
  8. Drug

    Aminophylline

    go.drugbank.com/drugs/DB01223
    ApprovedInvestigational

    Once in the body, theophylline is released and acts as a phosphodiesterase inhibitor, adenosine receptor blocker, and histone deacetylase activator.

    Categories: Purinergic P1 Receptor Antagonists, Cytochrome P-450 Substrates
  9. Drug

    Ticagrelor

    go.drugbank.com/drugs/DB08816
    ApprovedInvestigational

    [A204170,A2903] Ticagrelor is an ADP derivative developed for its P2Y<sub>12</sub> receptor antagonism.[A2903] Unlike [clopidogrel], ticagrelor is not a prodrug.

    Categories: Purinergic P2 Receptor Antagonists, Purinergic P2Y Receptor Antagonists
  10. Drug

    Rhein

    go.drugbank.com/drugs/DB13174
    Experimental

    Rhein is an anthraquinone metabolite of rheinanthrone and senna glycoside is present in many medicinal plants including Rheum palmatum, Cassia tora, Polygonum multiflorum, and Aloe barbadensis . It is known to have hepatoprotective, neph...

    Categories: Cytochrome P-450 CYP1A2 Inhibitors, Cytochrome P-450 CYP2C9 Inhibitors