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Displaying results 2241 - 2250 of 10000 in total
  1. Drug

    Upadacitinib

    go.drugbank.com/drugs/DB15091
    ApprovedInvestigational

    [A189171] The etiology of the disease is mostly unknown; however, the role of JAK as a driver of immune-mediated conditions was discovered, leading to the use of JAK as therapeutic targets for rheumatoid … [A189165] Despite a variety of therapeutic agents available for treatment, up to 40% of the patients do not respond to current therapies, including biological therapies.

    Products: RİNVOQ 15 MG UZATILMIŞ SALIMLI TABLET, 98 ADET, Rinvoq 45 mg Uzatılmış Salımlı Tablet, 28 ADET
  2. Drug

    Clesrovimab

    go.drugbank.com/drugs/DB18877
    Approved

    [A273953,A273978] Clesrovimab-cfor was approved by the US FDA in June 2025 for use in infants prior to or during their first RSV season.[L53228,L53233] … Clesrovimab is a fully human immunoglobulin G1 kappa (IgG1κ) monoclonal antibody targeted against the extracellular domain of the respiratory syncytial virus (RSV) fusion (F) protein.

  3. Drug

    Gemfibrozil

    go.drugbank.com/drugs/DB01241
    ApprovedInvestigational

    [L8525] Gemfibrozil was granted FDA approval on 21 December 1981.[L8525]

    Categories: Metabolic Side Effects of Drugs and SubstancesProducts: Nu-gemfibrozil Cap 300mg, Nu-gemfibrozil Tab 600mg
  4. Drug

    Certolizumab pegol

    go.drugbank.com/drugs/DB08904
    ApprovedInvestigational

    The absence of the Fc region was ideated to prevent complement fixation and antibody-mediated cytotoxicity as well as to markedly increase its half-life. … [A176606] It was developed and manufactured by UCB Pharma, first FDA approved in 2008[L45018] and updated for a new indication on March 28, 2019.[L5819]

    Products: CIMZIA 200 MG, CIMZIA 200 MG ILO IN FER
  5. Drug

    Tiopronin

    go.drugbank.com/drugs/DB06823
    Approved

    It is used after a failure of the non-pharmacological first line treatment consisting of increased fluid intake, restriction of sodium and protein, and urinary alkalinization. … Tiopronin is dosed on an individual basis using close monitoring of urinary cystine concentrations and urinary output.

  6. Drug

    Lomefloxacin

    go.drugbank.com/drugs/DB00978
    Approved

    Additionally, it has been employed for the prophylaxis of UTIs prior to surgery as well.

    Categories: Drugs for Treatment of TuberculosisProducts: LOMFLOX TABLET 400 mg, OKACIN GOZ DAMLASI 3 MG/ML 5 ML
  7. Drug

    Darolutamide

    go.drugbank.com/drugs/DB12941
    ApprovedInvestigational

    The goal of treatment with darolutamide is to delay the progression of prostate cancer to metastatic disease, increasing quality of life and life expectancy for those with advanced prostate cancer. … Darolutamide is a nonsteroidal androgen receptor antagonist for the treatment of castrate-resistant, non-metastatic prostate cancer (nmCRPC).

  8. Drug

    Moroctocog alfa

    go.drugbank.com/drugs/DB13999
    Approved

    Activation of Factor IX leads to a cascade of signals that results in activation of Factor X, which then results in the conversion of prothrombin to thrombin, and as a result, leads to the conversion of … Replacement of Factor VIII is essential for the treatment of Hemophilia A, which is caused by mutations in the Factor VIII gene, leading to a functional deficiency or complete loss of protein.

  9. Drug

    Tasonermin

    go.drugbank.com/drugs/DB11626
    Approved

    of the limbs as the product Beromun. … It was approved for use by the European Medicines Agency in April of 1999 for use as an adjunt to surgery for the subsequent removal of the tumor and in palliative care for irresectable soft tissue sarcoma

  10. Drug

    Fidanacogene elaparvovec

    go.drugbank.com/drugs/DB16783
    ApprovedInvestigational

    soft tissues or joints, and severe subcutaneous hematomas. … from week 12 to month 15 compared to an ABR of 4.43 for the pre-treatment period.