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Displaying results 2241 - 2250 of 10000 in total
  1. Drug

    Somatostatin

    go.drugbank.com/drugs/DB09099
    ApprovedInvestigationalWithdrawn

    It is secreted by the D cells of the islets to inhibit the release of insulin and glucagon, and is also generated in the hypothalamus, where it inhibits the release of growth hormone and thyroid-stimulating … [DB00104] is a long-acting analogue of somatostatin that inhibits the release of a number of hormones, and is clinically used to relieve symptoms of uncommon gastroenteropancreatic endocrine tumours, as

    Categories: P-glycoprotein substrates, Cytochrome P-450 CYP3A InhibitorsProducts: SOMATEX 3 MG I.V. İNFÜZYONLUK ÇÖZELTİ HAZIRLAMAK İÇİN TOZ VE ÇÖZÜCÜ, 1 FLAKON + 1 ÇÖZÜCÜ AMPUL, SOMATOSAN 3 MG IV INFUZYON ICIN 1 AMPUL
  2. Drug

    Benzgalantamine

    go.drugbank.com/drugs/DB19353
    ApprovedInvestigational

    [A264454] As a prodrug, benzagalantamine remains inert as it passes through the stomach, thereby avoiding many of the gastrointestinal effects associated with peripheral cholinesterase inhibition. … Benzgalantamine is a prodrug of [galantamine].

    Synonyms: 6h-benzofuro(3a,3,2-ef)(2)benzazepin-6-ol, 4a,5,9,10,11,12-hexahydro-3-methoxy-11-methyl-, benzoate (ester), (4as,6r,8as)-Categories: P-glycoprotein inhibitors, Cytochrome P-450 Substrates
  3. Drug

    Terpin hydrate

    go.drugbank.com/drugs/DB13163
    ApprovedWithdrawn

    Elixirs of terpin hydrate are still available to patients as prescription medications to be prepared by specialty compounding pharmacies. … It is derived from sources such as turpentine, oregano, thyme and eucalyptus.

    Synonyms: cis-p-methane-1,8-diol monohydrateMixtures: .-2 เอ็กซ์เพ็คท์
  4. Drug

    Glucarpidase

    go.drugbank.com/drugs/DB08898
    ApprovedInvestigational

    [L39855] Glucarpidase was first approved by the FDA in January 2012,[A7476] followed by the European Commission's approval in January 2022.[L39865] It is marketed as VORAXAZE. … In 1983, the gene for carboxypeptidase G2, or glucarpidase, was derived from _Pseudomonas_ sp. strain RS-16 to be cloned into _Escherichia coli_, allowing the enzyme to be produced in sufficient quantities

  5. Drug

    Patisiran

    go.drugbank.com/drugs/DB14582
    Approved

    It is marketed as Onpattro which is formulated as patisiran within a liposome envelope for better delivery to the liver, where transthyretin is produced. … Patisiran is a first in class short interfering RNA for the treatment of patients with polyneuropathy caused by hereditary transthyretin-mediated amyloidosis [L4220].

    Categories: Compounds used in a research, industrial, or household setting
  6. Drug

    Baclofen

    go.drugbank.com/drugs/DB00181
    ApprovedInvestigational

    [A245338] Baclofen was reintroduced in 1971 as a treatment for spasticity and was later approved by the FDA in 1977. … [L39429] Baclofen was investigated for use in alcohol dependence and withdrawal; however, evidence is limited and there is inconsistent evidence to suggest its clinical efficacy in managing alcohol

    Mixtures: Innoprax-5Categories: GABA-B Receptor Agonists
  7. Drug

    Meticillin

    go.drugbank.com/drugs/DB01603
    ApprovedInvestigational

    One of the penicillins which is resistant to penicillinase but susceptible to a penicillin-binding protein. It is inactivated by gastric acid so administered by injection.

    Synonyms: (2S,5R,6R)-6-[(2,6-dimethoxybenzoyl)amino]-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid, 6-(2,6-Dimethoxybenzamido)penicillanic acidCategories: Heterocyclic Compounds, 2-Ring
  8. Drug

    Ferric cation

    go.drugbank.com/drugs/DB13949
    ApprovedWithdrawn

    Iron is a transition metal with a symbol Fe and atomic number 26. By mass, it is the most common element on Earth. … Non-haem iron in food is mainly in the ferric state, which is the insoluble form of iron, and must be reduced to the ferrous cation for absorption [T28].

    Synonyms: iron(3+), Fe(III)Products: FERIMAX 100 MG/5 ML ORAL SOLUSYON 10 FLAKON, FERRUM HAUSMANN 100 MG/5 ML ORAL ÇÖZELTİ, 20 ADET
  9. Drug

    Kappadione

    go.drugbank.com/drugs/DB09332
    Approved

    It has been found to have carcinogenic potential in mammalian cells as well as cytotoxic properties [L1544]. … Kappadione is a Vitamin K derivative (chemically, it is menadiol sodium diphosphate), previously approved by FDA prior to 1982 and marketed by Lilly Marketing for this drug has been discontinued and is

  10. Drug

    Phosphorus

    go.drugbank.com/drugs/DB14151
    Approved

    Mixtures: Advanced B & T Formula, Nature"s Way Kids A+ Calcium + Vitamin D3 softgel capsules