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Displaying results 2251 - 2260 of 10000 in total
  1. Drug

    Denfivontinib

    go.drugbank.com/drugs/DB17159
    Investigational

    Synonyms: 8-Bromo-2-((1-methylpiperidin-4-yl)amino)-4-((4-phenoxyphenyl)amino)pyrido[4,3-D]pyrimidin-5(6H)-one, 8-bromo-2-[(1-methylpiperidin-4-yl)amino]-4-(4-phenoxyanilino)-6H-pyrido[4,3-d]pyrimidin-5-one
  2. Drug

    PF-07059013

    go.drugbank.com/drugs/DB18122
    Investigational

    Synonyms: 2(1h)-pyridinone, 6-((1s)-1-((2-amino-6-fluoro-3-quinolinyl)oxy)ethyl)-5-(1h-pyrazol-1-yl)-, 6-((1s)-1-((2-amino-6-fluoroquinolin-3-yl)oxy)ethyl)-5-(1h-pyrazol-1-yl)pyridin-2(1h)-one
  3. Drug

    Dipyridamole

    go.drugbank.com/drugs/DB00975
    ApprovedInvestigational

    A phosphodiesterase inhibitor that blocks uptake and metabolism of adenosine by erythrocytes and vascular endothelial cells. Dipyridamole also potentiates the antiaggregating action of prostacyclin.

    International brands: Cleridium 150Mixtures: Aspirin and Extended - Release Dipyridamole Capsules, 25 mg / 200 mg, Aspirin and Extended - Release Dipyridamole Capsules, 25 mg / 200 mg
  4. Drug

    Nemtabrutinib

    go.drugbank.com/drugs/DB18866
    Investigational

    Lymphoma (CLL/SLL) Without TP53 Aberrations (MK-1026-008, BELLWAVE-008)). … Nemtabrutinib is under investigation in clinical trial NCT05624554 (A Study of Nemtabrutinib vs Chemoimmunotherapy for Participants With Previously Untreated Chronic Lymphocytic Leukemia/small Lymphocytic

    Synonyms: 1,5-Anhydro-2-[[5-(2-chloro-4-phenoxybenzoyl)-7H-pyrrolo[2,3-d]pyrimidin-4-yl]amino]-2,3,4-trideoxy-D-erythro-hexitol, (2-chloro-4-phenoxyphenyl)(4-(((3r,6s)-6-(hydroxymethyl)tetrahydro-2h-pyran-3-yl)amino)-7h-pyrrolo(2,3-d)pyrimidin-5-yl)methanoneCategories: Heterocyclic Compounds, 1-Ring
  5. Drug

    Selegiline

    go.drugbank.com/drugs/DB01037
    ApprovedInvestigationalVet approved

    A selective, irreversible inhibitor of Type B monoamine oxidase. It is used in newly diagnosed patients with Parkinson's disease. … It may slow progression of the clinical disease and delay the requirement for levodopa therapy. It also may be given with levodopa upon onset of disability.

    Synonyms: L-DeprenalinCategories: P-glycoprotein inhibitors, Cytochrome P-450 Substrates
  6. Drug

    Esketamine

    go.drugbank.com/drugs/DB11823
    ApprovedInvestigational

    [L5596,A175462] On March 5, 2019, the nasal spray drug, _esketamine_, also known as _Spravato_ (by Janssen Pharmaceuticals), was approved by the FDA for treatment-resistant major depression. … The intranasal route of administration for this drug allows for easy administration and a fast onset of action, which sets it apart from many other antidepressant agents that may take several weeks to

    Synonyms: (S)-2-(o-chlorophenyl)-2-(methylamino)cyclohexanone, L-ketamineInternational brands: Keta-S, Ketanest S
  7. Drug

    Beclomethasone dipropionate

    go.drugbank.com/drugs/DB00394
    ApprovedInvestigational

    [L6871] It is a prodrug of an active metabolite beclomethasone 17-monopropionate (17-BMP)[A179839] which acts on the glucocorticoid receptor to mediates its therapeutic action. … Beclomethasone dipropionate itself posesses weak glucocorticoid receptor binding affinity and is rapidly converted into 17-BMP upon administration.

    Synonyms: (11β,16β)-9-chloro-11-hydroxy-16-methyl-17,21-bis(1-oxopropoxy)pregna-1,4-diene-3,20-dione, 9-chloro-11β-hydroxy-16β-methylpregna-1,4-diene-3,20-dione 17,21-dipropionateInternational brands: Clenil-A
  8. Drug

    Ciclopirox

    go.drugbank.com/drugs/DB01188
    ApprovedInvestigational

    Ciclopirox olamine (used in preparations called Batrafen, Loprox, Mycoster, Penlac and Stieprox) is a synthetic antifungal agent for topical dermatologic treatment of superficial mycoses.

    Synonyms: 6-cyclohexyl-1-hydroxy-4-methyl-2(1H)-pyridinoneMixtures: Ciclopirox 3% / Itraconazole 5% / Urea 20%, Ciclopirox Olamine 1% / Salicylic Acid 2%
  9. Drug

    Ketotifen

    go.drugbank.com/drugs/DB00920
    ApprovedInvestigational

    It has a similar structure to some other first-generation antihistamines such as [cyproheptadine] and [azatadine]. … [A231204] In the US, it is now used in an over-the-counter ophthalmic formulation for the treatment of itchy eyes associated with allergies,[L32278] and in Canada a prescription-only oral formulation is

    Categories: Heterocyclic Compounds, 1-RingProducts: KETOTIFENE EG, ZADITEN ORAL DAMLA 1 MG/ML, 25 ML
  10. Drug

    Betahistine

    go.drugbank.com/drugs/DB06698
    ApprovedInvestigational

    [A220333,L16403] Betahistine was first approved by the FDA in the 1970s but withdrawn within approximately 5 years due to a lack of evidence supporting its efficacy. … It has a significant impact on both the physical and social functioning of affected individuals.

    Synonyms: [2-(2-pyridyl)ethyl]methylamine, N-methyl-2-(2-pyridinyl)ethanamineCategories: Heterocyclic Compounds, 1-Ring