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Displaying results 221 - 230 of 10000 in total
  1. Drug

    Fenofibrate

    go.drugbank.com/drugs/DB01039
    ApprovedInvestigational

    [L8588,L8591] Fenofibrate was granted FDA approval on 31 December 1993.[L8585]

    Categories: simvastatin and fenofibrateProducts: Lipidil Ez, FENOFIBRATO EG
  2. Drug

    Phendimetrazine

    go.drugbank.com/drugs/DB01579
    ApprovedIllicit

    Phendimetrazine is chemically related to amphetamines and is a Schedule III drug under the Convention on Psychotropic Substances and in the US since 1970.

    Products: Fendique ER, Phendimetrazine Tartrate ER
  3. Drug

    Levosimendan

    go.drugbank.com/drugs/DB00922
    ApprovedInvestigationalWithdrawn

    Levosimendan is under investigation in clinical trial NCT00527059 (Renal Effects of Levosimendan in Patients Admitted With Acute Decompensated Heart Failure). … Levosimendan increases calcium sensitivity to myocytes by binding to troponin C in a calcium dependent manner. This increases contractility without raising calcium levels.

    Categories: Compounds used in a research, industrial, or household settingProducts: LEVOSIMENDAN EG, Levosimendan Carinopharm 12,5 mg Pulver für ein Konzentrat zur Herstellung einer Infusionslösung
  4. Drug

    Amsacrine

    go.drugbank.com/drugs/DB00276
    ApprovedInvestigationalWithdrawn

    It is effective in the treatment of acute leukemias and malignant lymphomas, but has poor activity in the treatment of solid tumors. … It is frequently used in combination with other antineoplastic agents in chemotherapy protocols. It produces consistent but acceptable myelosuppression and cardiotoxic effects.

    Categories: Compounds used in a research, industrial, or household settingProducts: Amlyo 75 mg Pulver für ein Konzentrat zur Herstellung einer Infusionslösung, Amsidyl 75 mg/1,5 ml Konzentrat und Lösungsmittel für ein Konzentrat zur Herstellung einer Infusionslösung
  5. Drug

    Pemetrexed

    go.drugbank.com/drugs/DB00642
    ApprovedInvestigational

    Its use in non-small cell lung cancer has also been investigated. Pemetrexed was first approved by the FDA in February 4, 2004.[A253907] … It is indicated for use in combination with cisplatin for the treatment of patients with malignant pleural mesothelioma whose disease is either unresectable or who are otherwise not candidates for curative

    Products: PEMETREXED EG, Pemetrexed Actavis 100 mg Pulver für ein Konzentrat zur Herstellung einer Infusionslösung
  6. Drug

    Sars-cov-2 virus spike protein

    go.drugbank.com/drugs/DB33830
    Experimental

    Synonyms: Sars-cov-2 virus spike protein
  7. Drug

    SAB-185

    go.drugbank.com/drugs/DB16491
    Investigational

    Synonyms: Anti-SARS-CoV-2 Polyclonal Antibodies SAB-185, ANTI-SARS-COV-2 HUMAN IMMUNOGLOBULIN INTRAVENOUS (TC BOVINE-DERIVED),
  8. Drug

    Inactivated SARS-Cov-2 Vaccine

    go.drugbank.com/drugs/DB15862
    Investigational

    Developed by Sinopharm's Wuhan Institute of Biological Products co., this vaccine consists of the WIV04 strain of SARS-CoV-2. … [A220158] Currently, the vaccine is being tested in Phase 3 clinical trial in Abu Dhabi (ChiCTR2000034780).[A219758]

  9. Drug

    BBV152

    go.drugbank.com/drugs/DB15847
    Investigational

    The candidate, a whole virion inactivated SARS-CoV-2 vaccine, was developed from a well-known SARS-CoV-2 strain and a vero cell platform (CCL-81) with adjuncts of either aluminum hydroxide gel (Algel) … The formulation with the TLR7/8 adjuvant specifically induced significant Th1 biased antibody responses and increased SARS-CoV-2 lymphocyte responses.

    Synonyms: Whole-Virion Inactivated SARS-CoV-2 Vaccine
  10. Drug

    Tazobactam

    go.drugbank.com/drugs/DB01606
    ApprovedInvestigational

    and mortality in hospitalized patients. … Piperacillin-tazobactam was initially approved by the FDA in 1994, and ceftolozane-tazobactam was approved by the FDA in 2014[FDA label], providing wider antibacterial coverage for gram-negative infections

    Mixtures: Zosyn Pharmacy Bulk Package, Zosyn Pharmacy Bulk PackageProducts: TAZOCIN EF