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Lefamulin
go.drugbank.com/drugs/DB12825ApprovedLefamulin is a pleuromutilin antibiotic used for the treatment of bacterial community-acquired pneumonia. … [L8093] This drug is the first semi-synthetic pleuromutilin that has been designed for systemic administration.
Categories: Antibacterials for Systemic Use, Antiinfectives for Systemic UseSparteine
go.drugbank.com/drugs/DB06727ApprovedWithdrawnSparteine is not currently FDA-approved for human use, and its salt, sparteine sulfate, is one of the products that have been withdrawn or removed from the market for reasons of safety or effectiveness … It is a sodium channel blocker, so it falls in the category of class 1a antiarrhythmic agents.
Categories: Antiarrhythmics, Class I, Antiarrhythmics, Class IaKappadione
go.drugbank.com/drugs/DB09332ApprovedKappadione is a Vitamin K derivative (chemically, it is menadiol sodium diphosphate), previously approved by FDA prior to 1982 and marketed by Lilly Marketing for this drug has been discontinued and is … not available in North America [L1543].
Salmeterol
go.drugbank.com/drugs/DB00938ApprovedInvestigationalSalmeterol is a long-acting beta-2 adrenergic receptor agonist drug that is currently prescribed for the treatment of asthma and chronic obstructive pulmonary disease COPD. … [A190459] Salmeterol was first described in the literature in 1988.[A190477] Salmeterol's structure is similar to salbutamol's with an aralkyloxy-alkyl substitution on the amine.
Mixtures: HOVID CLEFAN-S POWDER FOR INHALATION 50/250MCG, AIRFLUSAL FORSPIRO POWDER FOR INHALATION 50MCG/500MCGCategories: Drugs for Obstructive Airway Diseases, Agents to Treat Airway DiseaseNitrous acid
go.drugbank.com/drugs/DB09112ApprovedInvestigationalThere is also research to investigate its applicability towards treatments for heart attacks, brain aneurysms, pulmonary hypertension in infants, and Pseudomonas aeruginosa infections. … It is on the World Health Organization's List of Essential Medicines, a list of the most important medications needed in a basic health system.
Categories: Compounds used in a research, industrial, or household settingTabelecleucel
go.drugbank.com/drugs/DB17072ApprovedInvestigational[A253292,A253297,L43557] In October 2022, the EMA's Committee for Medicinal Products for Human Use (CHMP) recommended tabelecleucel be granted marketing authorization for the treatment of adult and … Both T-cells and B-cells are obtained from the same donor, and T-cells are grown to increase their numbers.
Deutetrabenazine
go.drugbank.com/drugs/DB12161ApprovedInvestigationalAs with other agents for the treatment of neurodegenerative diseases, deutetrabenazine is a drug to alleviate the motor symptoms of HD and is not proposed to halt the progression of the disease [T28]. … Deutetrabenazine depletes the levels of presynaptic dopamine by blocking VMAT2, which is responsible for the uptake of dopamine into synaptic vesicles in monoaminergic neurons and exocytotic release [A14081
Mixtures: Austedo XR, Austedo XRProducts: Austedo XREthchlorvynol
go.drugbank.com/drugs/DB00189ApprovedIllicitWithdrawnEthchlorvynol is a sedative and hypnotic drug. It has been used to treat insomnia, but has been largely superseded and is only offered where an intolerance or allergy to other drugs exists.
Synonyms: 1-Chloro-3-ethyl-pent-1-en-4-yn-3-ol, 1-chloro-3-ethyl-1-penten-4-yn-3-olInfluenza A virus A/Brisbane/02/2018 IVR-190 (H1N1) antigen (formaldehyde inactivated)
go.drugbank.com/drugs/DB15515ApprovedUpon re-exposure to infectious influenza virus, the immune system is prepared to identify and destroy the virus as there are circulating antibodies that recognize that particular component of the virus … Inactivated vaccines contain a virus particle that has been grown in media and then subsequently killed, or inactivated, through exposure to heat or chemicals such as formaldehyde 3.
Mixtures: Influvac Tetra, suspension for injection in pre-filled syringe, INFLUVAC TETRA, SUSPENSION FOR INJECTION IN PRE-FILLED SYRINGE 0.5 MLSebetralstat
go.drugbank.com/drugs/DB18305ApprovedInvestigationalSebetralstat is the first and only oral on-demand treatment for HAE, providing a convenient alternative to injectable therapies that have been challenging for patients to use [L53538, A274293]. … Food and Drug Administration approved sebetralstat on July 7, 2025, for treating acute HAE attacks in patients aged 12 years and older [L53533, L53538].
Categories: Drugs Used in Hereditary AngioedemaSynonyms: 1H-Pyrazole-4-carboxamide, N-[(3-fluoro-4-methoxy-2-pyridinyl)methyl]-3-methoxymethyl)-1-[[4-[(2-oxo-1(2H)-pyridinyl)methyl]phenyl]methyl]-, N-[(3-fluoro-4-methoxypyridin-2-yl)methyl]-3-(methoxymethyl)-1-({4-[(2-oxopyridin-1(2H)-yl)methyl]phenyl}methyl)-1H-pyrazol-4-carboxamide