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Allopurinol
go.drugbank.com/drugs/DB00437ApprovedInvestigationalThis disease has been well-documented in historical medical records and appears in the biographies of several prominent, historically recognized individuals [A175942]. … Gout is a disease that occurs by the deposition of monosodium urate crystals (MSU) in body tissues, especially around joints [A175942].
Synonyms: 1H-Pyrazolo(3,4-d)pyrimidin-4-ol, 4-Hydroxypyrazolo(3,4-d)pyrimidineCategories: Cytochrome P-450 CYP1A2 Inhibitors, Heterocyclic Compounds, 2-RingRocaglamide
go.drugbank.com/drugs/DB15495Experimental[A186760] Rocaglamides are secondary metabolites of the plant genus _Aglaia_, and extracts of the plant have traditionally been used as a form of insect repellant due to its natural insecticidal properties … Rocaglamide, also referred to as rocaglamide-A, is the eponymous member of a class of anti-cancer phytochemicals known as rocaglamides.
Categories: Heterocyclic Compounds, 2-RingRepaglinide
go.drugbank.com/drugs/DB00912ApprovedInvestigationalApproximately one month of therapy is required before a decrease in fasting blood glucose is seen. Meglitnides may have a neutral effect on weight or cause a slight increase in weight. … In addition to reducing postprandial and fasting blood glucose, meglitnides have been shown to decrease glycosylated hemoglobin (HbA1c) levels, which are reflective of the last 8-10 weeks of glucose control
Mixtures: REPAMEF 1/1000 MG EFERVESAN TABLET, 30 ADET, REPAMEF 1/500 MG EFERVESAN TABLET, 30 ADETCategories: Cytochrome P-450 Substrates, Heterocyclic Compounds, 1-RingSAR-endolysin
go.drugbank.com/bio_entities/BE0003269TargetEnterobacteria phage P1Signal-arrest-release (SAR) endolysin with lysozyme activity that degrades host peptidoglycans and participates with the pinholin and spanin proteins in the sequential events which lead to programmed host cell lysis releasing the mature ...
Synonyms: Gene product 17Protein S100-A16
go.drugbank.com/bio_entities/BE0008707TargetHumansCalcium-binding protein. Binds one calcium ion per monomer (PubMed:17030513). Can promote differentiation of adipocytes (in vitro) (By similarity). Overexpression in preadipocytes increases their proliferation, enhances adipogenesis and ...
Synonyms: Aging-associated gene 13 proteinXanomeline
go.drugbank.com/drugs/DB15357ApprovedInvestigational) and cognitive impairment have been attributed to decreased dopaminergic activity in mesocortical pathways. … Schizophrenia is a complex disease involving a number of different neurotransmitters, including serotonin, dopamine, and acetylcholine.
Categories: P-glycoprotein inhibitors, Cytochrome P-450 SubstratesMaralixibat
go.drugbank.com/drugs/DB16226ApprovedInvestigational[A239249] No clinical trials have been performed to assess the efficacy of these treatments for cholestatic pruritus and treatments were given based on a prescriber's clinical experience. … [A239249] Surgical interventions such as partial external bile diversion and ileal exclusion have also been used as treatments.
Categories: Cytochrome P-450 CYP3A Inhibitors, Heterocyclic Compounds, 2-RingInfluenza B virus B/Austria/1359417/2021 live (attenuated) antigen
go.drugbank.com/drugs/DB16902ApprovedInactivated vaccines contain a virus particle that has been grown in media and then subsequently killed, or inactivated, through exposure to heat or chemicals such as formaldehyde. … A seasonally-specific component of the influenza vaccine. The influenza vaccine, also known as the "flu shot", is a vaccine that helps to protect against infection from influenza viruses.
Synonyms: Influenza B virus B/Austria/1359417/2021 live, Influenza B virus B/Austria/1359417/2021 live (attenuated) antigenCategories: Live Attenuated Influenza B Virus VaccineInfluenza A virus A/Darwin/6/2021 IVR-227 (H3N2) antigen (formaldehyde inactivated)
go.drugbank.com/drugs/DB16903ApprovedWithdrawnInactivated vaccines contain a virus particle that has been grown in media and then subsequently killed, or inactivated, through exposure to heat or chemicals such as formaldehyde. … A seasonally-specific component of the influenza vaccine. The influenza vaccine, also known as the "flu shot", is a vaccine that helps to protect against infection from influenza viruses.
Synonyms: Influenza A virus A/Darwin/6/2021 IVR-227 (H3N2) antigen (formaldehyde inactivated)Categories: Inactivated Influenza A Virus VaccineInfluenza B virus B/Singapore/WUH4618/2021 antigen (MDCK cell derived, propiolactone inactivated)
go.drugbank.com/drugs/DB16910ApprovedInactivated vaccines contain a virus particle that has been grown in media and then subsequently killed, or inactivated, through exposure to heat or chemicals such as formaldehyde. … A seasonally-specific component of the influenza vaccine. The influenza vaccine, also known as the "flu shot", is a vaccine that helps to protect against infection from influenza viruses.
Synonyms: Influenza B virus B/Singapore/WUH4618/2021 antigen (MDCK cell derived, propiolactone inactivated)Categories: Inactivated Influenza B Virus Vaccine