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Displaying results 2331 - 2340 of 4190 in total
  1. Drug

    Fasudil

    go.drugbank.com/drugs/DB08162
    Investigational

    Fasudil has been investigated in Carotid Stenosis.

  2. Drug

    NS-2359

    go.drugbank.com/drugs/DB05805
    Investigational

    NS2359 is a triple monoamine re-uptake inhibitor with a new, unique drug profile expected to yield important benefits compared to existing treatments of depression. Enhancing the function of the three neurotransmitters serotonin, noradre...

  3. Drug

    AT9283

    go.drugbank.com/drugs/DB05169
    Investigational

    AT9283 is an aurora Kinase inhibitor developed by Astex Therapeutics for the treatment of cancer. It was discovered and developed internally using Astex’s fragment-based drug discovery platform, Pyramid.

  4. Drug

    LC16M8

    go.drugbank.com/drugs/DB05019
    Investigational

    LC16m8 is a next-generation, attenuated smallpox vaccine that is designed to have a better safety profile, yet be equally effective, compared to conventional smallpox vaccines. It is the only attenuated vaccine to be licensed for use in ...

  5. Drug

    ISS-1018

    go.drugbank.com/drugs/DB05463
    Investigational

    ISS 1018 is a short, synthetic, unmethylated CpG oligodeoxynucleotide (CpG ODN) with immunostimulatory activity. ISS 1018 signals through Toll-like receptor 9 (TLR9) to induce the production of immunoglobulin by B cells and interferon (I...

  6. Target

    Proline dehydrogenase 1, mitochondrial

    go.drugbank.com/bio_entities/BE0002330
    TargetEnzymeHumans

    Converts proline to delta-1-pyrroline-5-carboxylate

    Synonyms: p53-induced gene 6 protein
  7. Target

    Molybdenum cofactor biosynthesis protein 1

    go.drugbank.com/bio_entities/BE0011005
    TargetHumans

    Isoform MOCS1A and isoform MOCS1B probably form a complex that catalyzes the conversion of 5'-GTP to cyclic pyranopterin monophosphate (cPMP) (PubMed:11891227, PubMed:23627491, PubMed:29368224, PubMed:31996372). MOCS1A catalyzes the cycl...

    Synonyms: Cell migration-inducing gene 11 protein
  8. Drug

    Amfecloral

    go.drugbank.com/drugs/DB08924
    Experimental

    It acts as a prodrug which splits to form amphetamine and chloral hydrate, similarly to clobenzorex and related compounds, except that the N-substituent, in this case, yields a compound that is active

  9. Target

    Ferritin

    go.drugbank.com/bio_entities/BE0010292
    CarrierHumans

    Stores iron in a soluble, non-toxic, readily available form. Important for iron homeostasis. Has ferroxidase activity (PubMed:9003196). Iron is taken up in the ferrous form and deposited as ferric hydroxides after oxidation (PubMed:90031...

    Synonyms: Cell proliferation-inducing gene 15 protein
  10. Drug

    Tagraxofusp

    go.drugbank.com/drugs/DB14731
    ApprovedInvestigational

    Tagraxofusp is a CD123-directed cytotoxin. It is a fusion protein composed of a human interleukin-3 (IL-3) that is genetically fused to the catalytic and translocation domains of truncated diphtheria toxin (DT) produced in Escherichia co...