Search
Interleukin-15 receptor subunit alpha
go.drugbank.com/bio_entities/BE0010620TargetHumansHigh-affinity receptor for interleukin-15 (PubMed:8530383). Can signal both in cis and trans where IL15R from one subset of cells presents IL15 to neighboring IL2RG-expressing cells (By similarity).
Polypeptides: Interleukin-15 receptor subunit alphaSynonyms: IL-15R-alpha, IL-15 receptor subunit alphaCitrus bioflavonoids
go.drugbank.com/drugs/DB14586ApprovedMixtures: VITAMIN C 1000 MG WITH BIOFLAVONOIDS 100 MG, Rose Hips 500plus Nu LifeSynthetic Conjugated Estrogens, B
go.drugbank.com/drugs/DB09318ApprovedHowever, once a woman stops ovulating there is a sharp decline in the production of progesterone and estradiol by the ovaries and a consequent fluctuation in LH and FSH due to a lack of feedback control … Conjugated Equine Estrogens (CEEs) are derived from the urine of pregnant mares and contain a blend of at least 10 estrogen derivatives.
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A SubstratesEthylmorphine
go.drugbank.com/drugs/DB01466IllicitInvestigationalA narcotic analgesic and antitussive. It is metabolized in the liver by ethylmorphine-N-demethylase and used as an indicator of liver function. … In the US it is a schedule II drug (single-entity) and schedule III drug (in combination products).
Mixtures: FENOKODIN 20 MG / 10 MG TABLET, 20 ADET, ARKODIN TABLET, 15 ADETCategories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP2B6 SubstratesAminoglutethimide
go.drugbank.com/drugs/DB00357ApprovedWithdrawnAn aromatase inhibitor that produces a state of "medical" adrenalectomy by blocking the production of adrenal steroids. It also blocks the conversion of androgens to estrogens.
Categories: Cytochrome P-450 CYP3A Inducers, Cytochrome P-450 CYP2C19 InducersSynonyms: DL-AminoglutethimideSodium lauryl sulfate
go.drugbank.com/drugs/DB00815ApprovedSodium Lauryl Sulfate (SLS) is an anionic surfactant naturally derived from coconut and/or palm kernel oil. It usually consists of a mixture of sodium alkyl sulfates, mainly the lauryl. … SLS lowers surface tension of aqueous solutions and is used as fat emulsifier, wetting agent, and detergent in cosmetics, pharmaceuticals and toothpastes.
Mixtures: Trimo San, Trimo-SanCategories: Compounds used in a research, industrial, or household settingMe-4(18F)DG
go.drugbank.com/drugs/DB19207InvestigationalMe-4(18F)DG is under investigation in clinical trial NCT05558904 (An Investigational Scan (Me-4fdg PET/CT) for the Detection of Sodium-glucose Transport for Early Diagnosis of Lung Cancer).
Synonyms: -d-glucopyranoside, methyl 4-deoxy-4-(fluoro-18f)-, -methyl-4-(F-18)-fluoro-4-deoxy-d-glucopyranosidePralsetinib
go.drugbank.com/drugs/DB15822ApprovedInvestigational[A202055, A219751, L15986] Enhanced RET (Rearranged during transfection) oncogene expression is a hallmark of many cancers, including non-small cell lung cancer. … Pralsetinib, similar to the previously approved [selpercatinib], is a kinase inhibitor with enhanced specificity for RET tyrosine kinase receptors (RTKs) over other RTK classes.
Categories: Cytochrome P-450 CYP2C8 Inducers, Cytochrome P-450 SubstratesProguanil
go.drugbank.com/drugs/DB01131ApprovedProguanil is a prophylactic antimalarial drug, which works by stopping the malaria parasite, _Plasmodium falciparum_ and _Plasmodium vivax_, from reproducing once it is in the red blood cells.
Mixtures: Malarone 250 mg/100 mg Filmtabletten, MALARONE (250/100 MG TABLETS)Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP2C9 SubstratesInositol nicotinate
go.drugbank.com/drugs/DB08949ApprovedWithdrawnIt is used in food supplements as a source of niacin (vitamin B3), where hydrolysis of 1 g (1.23 mmol) inositol hexanicotinate yields 0.91 g nicotinic acid and 0.22 g inositol. … Inositol nicotinate, also known as Inositol hexaniacinate/hexanicotinate or "no-flush niacin", is a niacin ester and vasodilator.
Mixtures: Inositol Nicotinate 250 mg, Inositol Nicotinate 250 mg