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Displaying results 2341 - 2350 of 10000 in total
  1. Drug

    Lerodalcibep

    go.drugbank.com/drugs/DB19071
    ApprovedInvestigational

    [A275273] Lerodalcibep prevents the actions of PCSK9 and allows more LDL to bind to LDLR and be cleared from circulation.

    Synonyms: binding protein (1-96) anti-(human proprotein convertase subtilisin/kexin type 9), derived from human tenth fibronectin type iii domain, fused via peptidyl linker (97gsgsgs102) to human serum albumin (103
  2. Drug

    Insulin-like growth factor II

    go.drugbank.com/drugs/DB14472
    Investigational

    It is believed to be a major fetal growth factor in contrast to insulin-like growth factor I, which is a major growth factor in adults. … The insulin-like growth factor II is a well-characterized neutral peptide believed to be secreted by the liver and to circulate in the blood.

    Synonyms: CG-IGF2Products: HUCORD HSCM-100 Ampoule
  3. Drug

    Bamlanivimab

    go.drugbank.com/drugs/DB15718
    ApprovedInvestigational

    [L20979] Based on phase 2 clinical trial (BLAZE-1) interim results, bamlanivimab was granted Emergency Use Authorization (EUA) by the FDA on November 10, 2020. … [A224044, L20974] It is set to enter phase 3 clinical trials.

  4. Drug

    Domatinostat

    go.drugbank.com/drugs/DB17521
    Investigational

    Synonyms: 4SC-202, Hdac inhibitor 4sc-202
  5. Drug

    Vilanterol

    go.drugbank.com/drugs/DB09082
    ApprovedInvestigational

    [A259961] Vilanterol is 1000 and 400 fold more selective for β2 than β1 and β3 adrenoceptors, respectively, with a faster onset of action than salmeterol. … [L46481,L44461,L44456] BREO ELLIPTA is the first vilanterol-containing product to be approved by the FDA in May 2013, followed by ANORO ELLIPTA in December 2013 and TRELEGY ELLIPTA in September 2020.

    Mixtures: TRELEGY ELLIPTA INHALATION POWDER 100 MCG/62.5 MCG/25 MCG, RELVAR ELLIPTA 200/25 MCG KULLANIMA HAZIR INHALASYON TOZU ,14 DOZ
  6. Drug

    Centanafadine

    go.drugbank.com/drugs/DB14841
    ApprovedInvestigational

    [L63934] The FDA approved centanafadine on July 24, 2026, for the treatment of ADHD in adults and pediatric patients 6 years of age and older weighing at least 20 kg; use is not recommended below that … [L63806] Its mechanism in ADHD is unclear, but its efficacy may be mediated by this triple reuptake inhibition, which increases the availability of all three neurotransmitters in pathways involved in attention

  7. Drug

    Policresulen

    go.drugbank.com/drugs/DB13492
    Investigational

    Products: ALBOTHYL VAGINAL SUPPOSITORY 90 mg
  8. Drug

    Plutavimab

    go.drugbank.com/drugs/DB18856
    Investigational

    Plutavimab is under investigation in clinical trial NCT04900428 (Study to Evaluate a Single Intranasal Dose of STI-2099 (COVI-DROPS™) in Outpatient Adults With COVID-19 (UK)).

    Synonyms: Covi-amg, human monoclonal sti-2020 .kappa.
  9. Drug

    Mobocertinib

    go.drugbank.com/drugs/DB16390
    ApprovedInvestigationalWithdrawn

    [A238828] Mobocertinib appears to be an effective means of treating this otherwise treatment-resistant NSCLC, exerting an inhibitory effect on _EGFR_ exon 20 insertion mutant variants at concentrations … 1.5- to 10-fold lower than those required to inhibit wild-type EGFR.

  10. Drug

    Pramocaine

    go.drugbank.com/drugs/DB09345
    Approved

    It works by preventing ionic fluctuations needed for neuron membrane depolarization and action potential propagation. … It is used for many dermatological and anorectal/anogenital conditions including minor cuts/burns, insect bites, hives/rashes due to poison ivy exposure, hemorrhoids and other anorectal/anogenital disorders

    Mixtures: Oto End 10, Johnson and Johnson First Aid All Purpose 160 CTCategories: Antihistamines, Anesthetics, Etc.