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Plazomicin
go.drugbank.com/drugs/DB12615ApprovedIt was designed to evade all clinically relevant aminoglycoside-modifying enzymes, which contribute to the main resistance mechanism for aminoglycoside therapy [A33942]. … However, acquired resistance of aminoglycosides may arise through over expression of efflux pumps and ribosomal modification by bacteria, which results from amino acid or rRNA sequence mutations [A33942
Categories: Antibacterials for Systemic Use, Antiinfectives for Systemic UseCalcipotriol
go.drugbank.com/drugs/DB02300ApprovedInvestigationalCalcipotriol (INN) or calcipotriene (USAN) is a sythetic derivative of calcitriol or Vitamin D.
Mixtures: Enstilar 50 Mikrogramm/g + 0,5 mg/g Schaum zur Anwendung auf der HautCategories: Antipsoriatics for Topical UseColesevelam
go.drugbank.com/drugs/DB00930ApprovedInvestigationalColesevelam is a bile acid sequestrant. Colesevelam is used with exercise and diet changes (restriction of cholesterol and fat intake) to reduce the amount of cholesterol and certain fatty substances in the blood. It works by binding bil...
Categories: Hypolipidemic Agents Indicated for Hyperlipidemia, Non-statin Hypolipidemic Agents Indicated for HyperlipidemiaSodium borate
go.drugbank.com/drugs/DB14505ApprovedMixtures: Ma Ying Long Hemorrhoidal, Trimo San Deodorant Vaginal JellyPD-98059
go.drugbank.com/drugs/DB17042ExperimentalPD-98059 is an inhibitor of MAP-kinase kinase activation.[A253072]
Loxoprofen
go.drugbank.com/drugs/DB09212ApprovedInvestigationalA transdermal preparation was approved for use in Japan in January 2006.
Categories: Topical Products for Joint and Muscular Pain, Antiinflammatory Preparations, Non-Steroids for Topical UseEgg phospholipids
go.drugbank.com/drugs/DB14233ApprovedWithdrawnEgg phospholipids are available as an intravenous fat emulsion indicated as a source of calories for patients requiring parenteral nutrition.
Mixtures: KABIVEN EMULSION FOR INFUSION, LIPOFUNDIN N EMULSION FOR INFUSION 20 %Brincidofovir
go.drugbank.com/drugs/DB12151ApprovedInvestigationalBrincidofovir is an oral antiviral drug used in the treatment of human smallpox infections. … Brincidofovir, developed by Chimerix under the brand name Tembexa, was approved by the FDA for the treatment of smallpox infection in June 2021.
Categories: Antivirals for Systemic Use, Antiinfectives for Systemic UseXylitol
go.drugbank.com/drugs/DB11195ApprovedInvestigationalThe recommended dose of xylitol for dental caries prevention is 6–10 g/day, and most adults can tolerate 40 g/day without adverse events [A22081]. … Xylitol is a naturally occurring five-carbon sugar alcohol found in most plant material, including many fruits and vegetables. Xylitol-rich plant materials include birch and beechwood [A22081].
Piretanide
go.drugbank.com/drugs/DB02925Approvedan aromatic nucleus in the presence of other aromatically bonded functional groups. … Piretanide (INN, trade names Arelix, Eurelix, Tauliz) has been synthesized in 1973 at Hoechst AG (Germany) as a loop diuretic compound by using a then-new method for introducing cyclic amine residues in
Mixtures: RAMIPRIL HEXAL PL PIR5/6MG, RAMIPRIL HEXAL PL PIR5/6MG