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Narsoplimab
go.drugbank.com/drugs/DB16418ApprovedInvestigational[A241030] Evidence increasingly points to a role for the complement system in TMA. … [A241030, A241040] Mannan-associated lectin-binding serine protease-2 (MASP-2) is a major effector in the complement lectin pathway.
Synonyms: (1-445) (HOMO SAPIENS VH (IGHV2-26*01 (94%) (IGHD)-I, MASP-2 antibodyOzenoxacin
go.drugbank.com/drugs/DB12924Approveds Xepi (ozenoxacin 1%) as a topically applied cream indicated for the treatment of impetigo caused by *Staphylococccus aureus* or *Streptococcus pyogenes* in adult and pediatric patients 2 months of age … To date, ozenoxacin has been used in trials studying the treatment of impetigo. As of December 11, 2017 the FDA approved Ferrer Internacional S.A.'
Categories: Heterocyclic Compounds, 1-Ring, Heterocyclic Compounds, 2-RingTechnetium Tc-99m mebrofenin
go.drugbank.com/drugs/DB09137ApprovedWithdrawnThis is possible as Technetium-99m decays by isomeric transition to technetium-99 through the release of a gamma ray. … Technetium Tc 99m Mebrofenin is a diagnostic radiopharmaceutical composed of diisopropyl-iminodiacetic acid (DISIDA) attached to a technetium-99m ion.
Categories: Compounds used in a research, industrial, or household settingSynonyms: Bis(2-[[2-(3-bromo-2,4,6-trimethylanilino)-2-oxoethyl]-(carboxymethyl)amino]acetate) technetium, Technetium Tc 99m DISIDAOlsalazine
go.drugbank.com/drugs/DB01250Approved[A257063] Olsalazine is used in the treatment of ulcerative colitis.[L45023,L45151] … [A257078] Olsalazine comprises two mesalamine molecules joined by an azo bridge, which is cleaved in the colon.
Categories: Non COX-2 selective NSAIDSBimekizumab
go.drugbank.com/drugs/DB12917ApprovedInvestigational[L39665,L39680] It is the first IL-17 inhibitor to target both IL-17A and IL-17F. … [A244455] It has demonstrated superior efficacy as compared to another IL-17 inhibitor, [secukinumab], as well as [ustekinumab] (an IL-12/23 inhibitor) and [adalimumab] (a TNF inhibitor) in the treatment
Phosphatidyl serine
go.drugbank.com/drugs/DB00144ApprovedNutraceuticalIn apoptosis, phosphatidyl serine is transferred to the outer leaflet of the plasma membrane. This is part of the process by which the cell is targeted for phagocytosis. … Because of the potentail cognitive benefits of phosphatidylserine, the substance is sold as a dietary supplement to people who believe they can benefit from an increased intake.
Synonyms: PSInternational brands: LifeExtension PS CapsAvacincaptad pegol
go.drugbank.com/drugs/DB15165ApprovedInvestigationalAvacincaptad pegol is an RNA aptamer covalently bound to a branched polyethylene glycol (PEG) molecule. … This approval is based on the positive results obtained from 2 phase 3 clinical trials GATHER1 and GATHER2.[L47701]
Calcium polycarbophil
go.drugbank.com/drugs/DB14684ApprovedPolycarbophil is used to treat constipation. This drug may also be used to help relieve the symptoms of irritable bowel syndrome or diarrhea. … The material possesses exceptionally high water-binding capacity. is not absorbed, does not interfere with the activity of digestive enzymes or intestinal absorption, possesses satisfactory stability,
Categories: Compounds used in a research, industrial, or household settingProducts: FIBROSYL®, Best ChoiceCalcium levulinate
go.drugbank.com/drugs/DB13800ApprovedThe resultant calcium levulinate formulation, when used as a calcium supplement, possesses a high calcium content that is observed to be 14.8% higher than the content typically found in calcium lactate … The relatively new calcium levulinate is produced from a direct reaction between L- or levulinic acid levulose and calcium hydroxide [L2765].
Mixtures: CALCIUM PICKEN %10 ENJEKSİYONLUK ÇÖZELTİ AMPUL, 5 ADET, CALCİLES 225 MG+572 MG/10 ML ENJEKSİYONLUK ÇÖZELTİ, 5 ADETFludrocortisone
go.drugbank.com/drugs/DB00687ApprovedInvestigational[A187169,A187187] It is functionally similar to [aldosterone], the body's primary endogenous mineralocorticoid, and is structurally analogous to [cortisol], differing only by a fluorine atom at the 9-position … of the steroid structure - this fluorination is thought to be crucial to fludrocortisone's significant mineralocorticoid potency.
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A SubstratesProducts: ASTONIN® H TABLETAS, Astonin - H - Tabletten