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Ozenoxacin is a quinolone antibiotic used to treat impetigo caused by susceptible bacteria. To date, ozenoxacin has been used in trials studying the treatment of impetigo.
- Mechanism
- Curator reviewed · 1 reference
Ozenoxacin is a quinolone antibiotic drug. And, like most quinolones, ozenoxacin predominately executes its mechanism of action by entering into bacterial cells and acting to inhibit the bacterial DNA replication enzymes DNA gyrase A and topoisomerase IV.
As DNA gyrase A and topoisomerase IV are essential to bacterial DNA replication activities including supercoiling, supercoil relaxation, chromosomal condensation, chromosomal decatenation and more, their inhibition is the principal action of ozenoxacin's mechanism and it has been demonstrated to be bactericidal against S. aureus and S. pyogenes organisms.
- Primary indication
- Ozenoxacin cream is indicated for the topical treatment of impetigo caused by Staphylococcus aureus or Streptococcus pyogenes in patients aged 2 months of age and older.Curator reviewed · 1 structured indication
- Formula / weight
- C21H21N3O3 · 363.417 g/mol (avg)
- First approval
- Canada, 2017 · United States, 2017
- Brand names
- Ozanex
Resolves to
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Which drugs share a target with Ozenoxacin, and which of those have an active Phase 3 trial?