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Displaying results 2401 - 2410 of 10000 in total
  1. Drug

    Seletracetam

    go.drugbank.com/drugs/DB05885
    Investigational

    Seletracetam is a pyrrolidone derivative and with a structural similarity to newer generation antiepileptic drug levetiracetam. … As of 2010, its production was further halted due to the investigation of a newer antiepileptic agent, brivaracetam.

    Synonyms: (2S)-2-((4S)-4-(2,2-Difluoroethenyl)-2-oxopyrrolidin-1-yl)butanamideCategories: Cytochrome P-450 Substrates, Heterocyclic Compounds, 1-Ring
  2. Drug

    AM365

    go.drugbank.com/drugs/DB06564
    Experimental

    Detiviciclovir (AM365) is an antiviral nucleoside analogue.

    Synonyms: 2-((2-AMINO-9H-PURIN-9-YL)METHYL)PROPANE-1,3-DIOL
  3. Drug

    5,7,2′-trihydroxy-6,8-dimethoxyflavone

    go.drugbank.com/drugs/DB13983
    Experimental

    5,7,2′-trihydroxy-6,8-dimethoxyflavone (K36) is a high-affinity, naturally occurring flavonoid derivative isolated from the medicinal herb _Scutellaria baicalensis_ Georgi [A31656].

    Synonyms: 5,7-Dihydroxy-2-(2-hydroxyphenyl)-6,8-dimethoxy-4H-1-benzopyran-4-one
  4. Drug

    ADAM I-123

    go.drugbank.com/drugs/DB19213
    Investigational

    ADAM I-123 is under investigation in clinical trial NCT01160263 (Study of Dopamine and Serotonin Transporters in Patients With Amyotrophic Lateral Sclerosis and Controls).

    Synonyms: Benzenemethanamine, 2-((2-amino-4-(iodo-123i)phenyl)thio)-n,n-dimethyl-
  5. Drug

    RWJ-56423

    go.drugbank.com/drugs/DB02812
    Experimental

    Synonyms: (2S,4R)-1-acetyl-N-[(2S)-1-(1,3-benzothiazol-2-yl)-5-(diaminomethylideneamino)-1-oxopentan-2-yl]-4-hydroxypyrrolidine-2-carboxamide
  6. Drug

    Onternabez

    go.drugbank.com/drugs/DB18076
    Experimental

    Synonyms: [(1S,2S,5S)-2-[2,6-dimethoxy-4-(2-methyloctan-2-yl)phenyl]-6,6-dimethyl-4-bicyclo[3.1.1]hept-3-enyl]methanol
  7. Drug

    Oxogluric acid

    go.drugbank.com/drugs/DB08845
    InvestigationalNutraceutical

    In the United States a phase I clinical trial is investigating whether oxogluric acid precursors found in nutritional supplements can benefit patients with the metabolic disorder propionic acidemia. … studies have shown a reduction in ammonia by oxogluric acid in hemodialysis patients.

    Synonyms: 2-Ketoglutaric acid, 2-oxoglutaric acid
  8. Drug

    Empagliflozin

    go.drugbank.com/drugs/DB09038
    ApprovedInvestigational

    Empagliflozin is an inhibitor of sodium-glucose co-transporter-2 (SGLT2), the transporters primarily responsible for the reabsorption of glucose in the kidney. … [A203453] It is used clinically as an adjunct to diet and exercise, often in combination with other drug therapies,[L13673,L13679,L11479] for the management of type 2 diabetes mellitus.

    Synonyms: 1-chloro-4-(glucopyranos-1-yl)-2-(4-(tetrahydrofuran-3-yloxy)benzyl)benzene, (1S)-1,5-anhydro-1-(4-chloro-3-{4-[(3S)-tetrahydrofuran-3-yloxy]benzyl}phenyl)-D-glucitolMixtures: GLYXAMBI® 25 MG/ 5 MG, GLYXAMBI® 25 MG/ 5 MG
  9. Drug

    Raxtozinameran

    go.drugbank.com/drugs/DB18228
    ApprovedInvestigational

    It works by binding to the spike (S) protein of severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2), which is a transmembrane glycoprotein that plays a vital role in viral pathogenesis, evolutions

    Synonyms: RNA (recombinant 5′-[1,2-[(3′-O-methyl)m7G-(5′→5′)-ppp-Am]]-capped all uridine→N1-methylpseudouridine-substituted severe acute respiratory syndrome coronavirus 2 spike glycoprotein secretory signal peptide, messenger RNA (mRNA), 5'-capped, encoding a full-length, codon-optimised pre-fusion stabilised conformation variant (K982P and V983P) of the SARS-CoV-2 (severe acute respiratory syndrome coronavirus 2)Products: COMIRNATY® VACUNA DE ARNM CONTRA COVID-19
  10. Drug

    K-00546

    go.drugbank.com/drugs/DB07664
    Experimental

    Synonyms: CDK1/2 inhibitor III