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Efbemalenograstim alfa
go.drugbank.com/drugs/DB18704ApprovedInvestigationalEfbemalenograstim alfa is a long-acting recombinant fusion protein of granulocyte-colony stimulating factor (G-CSF) due to the addition of the Fc portion of human IgG2, allowing for once-per-cycle administration … [L48852,A262167] As endogenous G-CSF mediates the differentiation of hematopoietic stem cells into granulocytes and eventually neutrophils, the administration of recombinant G-CSF like efbemalenograstim
Hydrocortisone acetate
go.drugbank.com/drugs/DB14539ApprovedInvestigationalVet approvedMixtures: Alcortin A, Alcortin AProducts: Poli-AAlpelisib
go.drugbank.com/drugs/DB12015ApprovedInvestigationalAlpelisib was designed to target this enzyme that appears to be mutated at a rate of nearly 30% in human cancers, leading to hyperactivation. … It works by selectively inhibiting class I PI3K p110α [A179203], which is the catalytic subunit of PI3K, a lipid kinase that plays a role in various biological processes, including proliferation, survival
Categories: Cytochrome P-450 CYP3A4 Substrates with a Narrow Therapeutic IndexC326
go.drugbank.com/drugs/DB06017ExperimentalThe drug is composed of an IL-6–binding trimer and a IgG-binding domain. … C326 is an investigational compound under investigation in clinical trial NCT00353756 (Phase 1 Study of Safety and Biological Effects of C326, an Inhibitor of IL-6, in Crohn's Disease) for the treatment
Toluene
go.drugbank.com/drugs/DB11558InvestigationalVet approvedToluene is a colorless, liquid that is immiscible in water. It is a mono-substituted benzene derivative used in veterinary medicine as a treatment for various parasites in dogs and cats.
Categories: Compounds used in a research, industrial, or household settingThiopental
go.drugbank.com/drugs/DB00599ApprovedInvestigationalVet approvedWithdrawnA barbiturate that is administered intravenously for the induction of general anesthesia or for the production of complete anesthesia of short duration.
Categories: Cytochrome P-450 CYP2C19 Substrates with a Narrow Therapeutic IndexLumiliximab
go.drugbank.com/drugs/DB06162InvestigationalLumiliximab is a chimeric monoclonal antibody which is used as an immunosuppressive drug. … It is a primatized anti-CD23 macaque/human chimeric antibody that inhibits the production of the IgE antibody, for the potential treatment of allergic conditions.
Metrizamide
go.drugbank.com/drugs/DB01578ExperimentalIt is also used as a resorbable, non-ionic contrast medium. … Metrizamide is a solute for density gradient centrifugation offering higher maximum solution density without the problems of increased viscosity.
Categories: Compounds used in a research, industrial, or household setting