Toluene

DB11558InvestigationalVet approvedSmall molecule

Toluene is a colorless, liquid that is immiscible in water. It is a mono-substituted benzene derivative used in veterinary medicine as a treatment for various parasites in dogs and cats.

Mechanism: Pharmacologically active on NMDA receptor
Curator reviewed
Primary indication: Used for the removal of ascarids (Toxocara canis and Toxascaris leonina) and hookworms (Ancylostoma caninum and Uncinaria stenocephala) and as an aid in removing tapeworms (Taenia pisiformis, Dipylidium caninum, and Echinococcus granulosus) from dogs and...Curator reviewed
Formula / weight: C₇H₈ · 92.1384 g/mol (avg)
Code names: NSC-406333

Resolves to

Compound

UNII3FPU23BG52CAS108-88-3ChEMBLCHEMBL9113ChEBI17578PubChem1140KEGGC01455

Clinical / RWD

RxNorm1311381

Structure

InChIKeyYXFVVABEGXRONW-UHFFFAOYSA-NSMILESCC1=CC=CC=C1

What you can answer from here — as of July 07, 2026

1Protein targetEach mapped to UniProt, with action and pharmacological action

Listed above

3Clinical trialsPhase, status and sponsor resolved per trial

6+ReferencesStructured and connected to the statements they support

Which companies are running trials of Toluene, in which indications and phases, and which of those programs are still active?

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