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Displaying results 2431 - 2440 of 10000 in total
  1. Drug

    Nicotine

    go.drugbank.com/drugs/DB00184
    ApprovedInvestigational

    It is the prototypical agonist at nicotinic cholinergic receptors where it dramatically stimulates neurons and ultimately blocks synaptic transmission.

    Synonyms: (S)-3-(1-methylpyrrolidin-2-yl)pyridine, (S)-3-(N-methylpyrrolidin-2-yl)pyridineCategories: Heterocyclic Compounds, 1-Ring, Cytochrome P-450 Substrates
  2. Drug

    TK-112690

    go.drugbank.com/drugs/DB18822
    Investigational

    Synonyms: O2,2'-anhydro-5-methyluridine, 6h-furo(2',3':4,5)oxazolo(3,2-a)pyrimidin-6-one, 2,3,3a,9a-tetrahydro-3-hydroxy-2-(hydroxymethyl)-7-methyl-, (2r,3r,3as,9ar)-
  3. Drug

    (5S)-5-(2-amino-2-oxoethyl)-4-oxo-N-[(3-oxo-3,4-dihydro-2H-1,4-benzoxazin-6-yl)methyl]-3,4,5,6,7,8-hexahydro[1]benzothieno[2,3-d]pyrimidine-2-carboxamide

    go.drugbank.com/drugs/DB07397
    Experimental

    Synonyms: (5S)-5-(2-amino-2-oxoethyl)-4-oxo-N-[(3-oxo-3,4-dihydro-2H-1,4-benzoxazin-6-yl)methyl]-3,4,5,6,7,8-hexahydro[1]benzothieno[2,3-d]pyrimidine-2-carboxamide
  4. Drug

    Interferon alfa-2b

    go.drugbank.com/drugs/DB00105
    ApprovedInvestigational

    It is used extensively as an antiviral or antineoplastic agent. … A type I interferon consisting of 165 amino acid residues with arginine in position 23. This protein is produced by recombinant DNA technology and resembles interferon secreted by leukocytes.

    Synonyms: Interferon alfa 2-b, Intron AMixtures: Rebetron Ready To Use Solution (albumin(human)free) (6000000 Iu/ml and 200mg Capsules), Rebetron Solution (albumin (human) Free) (18 Miu Multi-dose Pen / 200mg Capsules)
  5. Drug

    Triamcinolone

    go.drugbank.com/drugs/DB00620
    ApprovedInvestigationalVet approved

    [L8255] Triamcinolone can be used as a one time adjunct treatment of osteoarthritic knee pain,[L8264] or first line as a topical treatment of corticosteroid responsive dermatoses. … [L8246,L8249,L8252,L8255,L8258,L8261,L8264] Triamcinolone was granted FDA approval on 3 December 1957.

    Synonyms: 9-fluoro-11β,16α,17,21-tetrahydroxypregna-1,4-diene-3,20-dioneInternational brands: Omcilon-A
  6. Drug

    Metformin

    go.drugbank.com/drugs/DB00331
    ApprovedInvestigational

    It is commonly described as an "insulin sensitizer", leading to a decrease in insulin resistance and a clinically significant reduction of plasma fasting insulin levels. … Metformin is a biguanide antihyperglycemic agent and first-line pharmacotherapy used in the management of type II diabetes.

    Mixtures: DAPAKEM-M 10/1000, XIGDUO XR (TABLETS 10 MG/1000 MG)Categories: MATE 1 Substrates, MATE 2 Substrates
  7. Drug

    Ibandronate

    go.drugbank.com/drugs/DB00710
    ApprovedInvestigational

    [A203138] Ibandronate was granted FDA approval on 16 May 2003.[L13805] … [A203111,A203138] It is used to prevent and treat postmenopausal osteoporosis.[L13805,L13808] Ibandronate was first described in the literature in 1993 as a treatment for bone loss in dogs.

    Mixtures: IBAMIN D3 150 MG/2800 IU FİLM KAPLI TABLET, 3 ADET, İBAMIN D3 150 MG/2800 IU GRANÜL İÇEREN SAŞE ,3 SAŞEProducts: ACIDO IBANDRONICO EG, BONDRONAT 2 MG/2 ML AMPUL, 5 ADET
  8. Drug

    Nimesulide

    go.drugbank.com/drugs/DB04743
    ApprovedWithdrawn

    Nimesulide is a relatively COX-2 selective, non-steroidal anti-inflammatory drug (NSAID) with analgesic and antipyretic properties. … Its approved indications are the treatment of acute pain, the symptomatic treatment of osteoarthritis and primary dysmenorrhoea in adolescents and adults above 12 years old.

    Mixtures: ETNA COMBO 100 MG/8 MG TABLET, 14 ADET, NİMES COMBO 100 MG / 8 MG TABLET , 14 ADETCategories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A Substrates
  9. Drug

    Vinblastine

    go.drugbank.com/drugs/DB00570
    ApprovedInvestigational

    (Merck, 11th ed.)

    Categories: P-glycoprotein substrates with a Narrow Therapeutic Index, Cytochrome P-450 CYP3A4 Substrates with a Narrow Therapeutic IndexProducts: VINCABLAS® 10 MG/VIAL, VINBLASTINE RICHTER 5 MG FLAKON
  10. Drug

    Vericiguat

    go.drugbank.com/drugs/DB15456
    ApprovedInvestigational

    [A227458,A227488] Cyclic GMP acts as a second messenger, activating a number of downstream signaling cascades that elicit a broad variety of effects, and these diverse cellular effects have implicated … [A227458] As a direct stimulator of sGC, vericiguat mitigates the need for a functional NO-sGC-cGMP axis and thereby helps to prevent the myocardial and vascular dysfunction associated with decreased sGC

    Categories: Heterocyclic Compounds, 1-Ring, P-glycoprotein substratesProducts: VERQUVO 5 MG FİLM KAPLI TABLET , 14 ADET, VERQUVO 10 MG FİLM KAPLI TABLET , 14 ADET