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Adlinacogene civaparvovec
go.drugbank.com/drugs/DB16788Investigational[L46711] Developed by Sangamo Therapeutics Inc., it is being investigated for the treatment of hemophilia B.[L46706] … Adlinacogene civaparvovec is an investigational _in vivo_ genome editing therapeutic product.
Lixmabegagene relduparvovec
go.drugbank.com/drugs/DB16816InvestigationalLixmabegagene relduparvovec, formerly known as LYS-GM101, is a recombinant adeno-associated virus vector serotype rh.10 (AAVrh.10) carrying the human β-galactosidase gene (GBL1). … It is under development for the treatment of GM1 gangliosidosis.[L45929]
Repotrectinib
go.drugbank.com/drugs/DB16826ApprovedInvestigationalRepotrectinib is a next-generation tyrosine kinase inhibitor (TKI) specifically designed to address resistance in the treatment of non-small cell lung cancer (NSCLC), specifically due to mutations in the … This approval is based on favorable results from the TRIDENT-1 study, where the objective response rate was 79% in TKI-naive patients and 38% in TKI-pretreated patients respectively.[L48741]
Categories: MATE 2 Inhibitors, P-glycoprotein inhibitorsSynonyms: (3R,6S,)-45-FLUORO-3,6-DIMETHYL-5-OXA-2,8-DIAZA-1(5,3)-PYRAZOLO(1,5-A)PYRIMIDINA-4(1,2)-BENZENANONAPHAN-9-ONE, (7S,13R)-11-Fluoro-7,13-Dimethyl-6,7,13,14-Tetrahydro-1,15-Ethenopyrazolo[4,3-F][1,4,8,10]Benzoxatriazacyclotridecin-4(5H)-OneAZD-7648
go.drugbank.com/drugs/DB16834InvestigationalCategories: Heterocyclic Compounds, 1-Ring, Heterocyclic Compounds, 2-RingPidnarulex
go.drugbank.com/drugs/DB16846InvestigationalCategories: Heterocyclic Compounds, 1-Ring, Heterocyclic Compounds, 2-RingOlprinone
go.drugbank.com/drugs/DB16847InvestigationalCategories: Heterocyclic Compounds, 1-Ring, Phosphodiesterase 3 InhibitorsRhodamine B
go.drugbank.com/drugs/DB16853ExperimentalCategories: P-glycoprotein substrates, Heterocyclic Compounds, 3-RingFurfural
go.drugbank.com/drugs/DB16856ExperimentalSynonyms: 2-Formylofuran, 2-Furil-metanaleCategories: Heterocyclic Compounds, 1-RingButylated hydroxytoluene
go.drugbank.com/drugs/DB16863InvestigationalCategories: Compounds used in a research, industrial, or household setting