Pidnarulex

DB16846InvestigationalSmall molecule

Pidnarulex: Overview.

Mechanism: Pharmacologically active on DNA-directed RNA polymerase I subunit RPA1, DNA-directed RNA polymerase I subunit RPA49, and DNA-directed RNA polymerase I subunit RPA2
Curator reviewed
Formula / weight: C₂₇H₂₇N₇O₂S · 513.62 g/mol (avg)
Code names: CX-5461

Resolves to

Compound

Structure

InChIKeyXGPBJCHFROADCK-UHFFFAOYSA-NSMILESCN1CCCN(CC1)C1=NC2=C(C=C1)C(=O)C(C(=O)NCC1=NC=C(C)N=C1)=C1SC3=CC=CC=C3N21

Targets

What you can answer from here — as of July 08, 2026

3Protein targetsEach mapped to UniProt, with action and pharmacological action

Listed above

7Clinical trialsPhase, status and sponsor resolved per trial

3+ReferencesStructured and connected to the statements they support

Which drugs share a target with Pidnarulex, and which of those have an active Phase 3 trial?

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