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N-[3-(Dimethylamino)Propyl]-2-({[4-({[4-(Formylamino)-1-Methyl-1h-Pyrrol-2-Yl]Carbonyl}Amino)-1-Methyl-1h-Pyrrol-2-Yl]Carbonyl}Amino)-5-Isopropyl-1,3-Thiazole-4-Carboxamide
go.drugbank.com/drugs/DB02295ExperimentalSynonyms: N-[3-(Dimethylamino)Propyl]-2-({[4-({[4-(Formylamino)-1-Methyl-1h-Pyrrol-2-Yl]Carbonyl}Amino)-1-Methyl-1h-Pyrrol-2-Yl]Carbonyl}Amino)-5-Isopropyl-1,3-Thiazole-4-CarboxamideIdasanutlin
go.drugbank.com/drugs/DB12325InvestigationalIdasanutlin has been used in trials studying the treatment of Neoplasms, Non-Hodgkin's Lymphoma, Leukemia, Myeloid, Acute, Recurrent Plasma Cell Myeloma, and Neoplasms, Leukemia, Acute Myeloid Leukemia
Categories: Heterocyclic Compounds, 1-Ring, Proto-Oncogene Proteins c-mdm2, antagonists & inhibitorsSynonyms: BENZOIC ACID, 4-((((2R,3S,4R,5S)-3-(3-CHLORO-2-FLUOROPHENYL)-4-(4-CHLORO-2-FLUOROPHENYL)-4-CYANO-5-(2,2-DIMETHYLPROPYL)-2-PYRROLIDINYL)CARBONYL)AMINO)-3-METHOXY-Coenzyme F420
go.drugbank.com/drugs/DB03913ExperimentalSynonyms: N-{N-[O-(7,8-didemethyl-8-hydroxy-5-deazariboflavin phospho)-(S)-lactyl]-γ-L-glutamyl}-L-glutamate, coenzyme γ-F420-2Categories: Enzymes and Coenzymes, Heterocyclic Compounds, 2-RingHydrocortisone
go.drugbank.com/drugs/DB00741ApprovedInvestigationalVet approved[L10529,L10532,L10535,L10538,L7772,L7321] It was discovered in the 1930s by Edward Kendall and named Compound F, or 17-hydroxycorticosterone. … [A188420] Hydrocortisone was granted FDA approval on 5 August 1952.[L10574]
Synonyms: Reichstein's substance M, 17-HydroxycorticosteroneInternational brands: Polcort H, Preparation H Hydrocortisone CreamNaproxen
go.drugbank.com/drugs/DB00788ApprovedInvestigationalVet approved[A179098] Given its overall tolerability and effectiveness, naproxen can be considered a first line treatment for a variety of clinical situations requiring analgesia. … Naproxen is classified as a nonsteroidal anti-inflammatory dug (NSAID) and was initially approved for prescription use in 1976 and then for over-the-counter (OTC) use in 1994.
Synonyms: (+)-(S)-6-Methoxy-α-methyl-2-naphthaleneacetic acid, (S)-2-(6-Methoxy-2-naphthyl)propanoic acidInternational brands: Bumaflex N, Proxen SErdosteine
go.drugbank.com/drugs/DB05057ApprovedInvestigationalErdosteine is a drug that causes a breakdown of mucus, also known as a _mucolytic_ agent. … Erdosteine is associated with a low incidence of adverse events, most of which are gastrointestinal and generally mild.
Categories: Heterocyclic Compounds, 1-Ring, Cough and Cold PreparationsProducts: ENZEVİN 175 MG/5 ML SUSPANSIYON ICIN KURU TOZ, 100 ML, EVOSTEN 175 MG/5 ML ORAL SÜSPANSİYON HAZIRLAMAK İÇİN TOZ, 100 MLNorclobazam
go.drugbank.com/drugs/DB17092InvestigationalSynonyms: 1h-1,5-benzodiazepine-2,4(3h,5h)-dione, 8-chloro-1-phenyl-7-chloro-5-phenyl-1,2,4,5-tetrahydro-3h-1,5-benzodiazepine-2,4-dione, Clobazam metabolite m9Categories: Cytochrome P-450 Substrates, Heterocyclic Compounds, 2-RingAtorvastatin
go.drugbank.com/drugs/DB01076ApprovedInvestigational[A181087, A181406] Some evidence has shown that even for low-risk individuals (with <10% risk of a major vascular event occurring within five years) statin use leads to a 20%-22% relative reduction in … More specifically, statin medications competitively inhibit the enzyme hydroxymethylglutaryl-coenzyme A (HMG-CoA) Reductase,[A181421] which catalyzes the conversion of HMG-CoA to mevalonic acid.
Mixtures: Triveram 10 mg/5 mg/5 mg Filmtabletten, TRIVERAM FILM-COATED TABLET 10 mg/5 mg/5 mgCategories: Heterocyclic Compounds, 1-Ring, atorvastatin and ezetimibeTrazodone
go.drugbank.com/drugs/DB00656ApprovedInvestigational[T646] A unique feature of this drug is that it does not promote the anxiety symptoms, sexual symptoms, or insomnia, which are commonly associated with SSRI and SNRI therapy. … [T646] Trazodone acts on various receptors, including certain histamine, serotonin, and adrenergic receptors, distinguishing it from other antidepressants that cover a narrow range of neurotransmitters
Categories: Peripheral alpha-1 blockers, Adrenergic alpha-1 Receptor AntagonistsSynonyms: 2-(3-[4-(3-chlorophenyl)-1-piperazinyl]propyl)[1,2,4]triazolo[4,3-a]pyridin-3(2H)-oneAmantadine
go.drugbank.com/drugs/DB00915ApprovedInvestigationalAn antiviral that is used in the prophylactic or symptomatic treatment of influenza A. It is also used as an antiparkinsonian agent, to treat extrapyramidal reactions, and for postherpetic neuralgia. … The mechanisms of its effects in movement disorders are not well understood but probably reflect an increase in synthesis and release of dopamine, with perhaps some inhibition of dopamine uptake.
Mixtures: Innoprax-5, ROSEL-TCategories: Influenza A M2 Protein Inhibitor, M2 Protein Inhibitors