Idasanutlin

DB12325InvestigationalSmall molecule

Idasanutlin has been used in trials studying the treatment of Neoplasms, Non-Hodgkin's Lymphoma, Leukemia, Myeloid, Acute, Recurrent Plasma Cell Myeloma, and Neoplasms, Leukemia, Acute Myeloid Leukemia.

Chemical structure of Idasanutlin
Formula / weight
C31H29Cl2F2N3O4 · 616.49 g/mol (avg)
Also known as
BENZOIC ACID, 4-((((2R,3S,4R,5S)-3-(3-CHLORO-2-FLUOROPHENYL)-4-(4-CHLORO-2-FLUOROPHENYL)-4-CYANO-5-(2,2-DIMETHYLPROPYL)-2-PYRROLIDINYL)CARBONYL)AMINO)-3-METHOXY-
Code names
RG-7388 · RO-5503781

Resolves to

Compound
UNIIQSQ883V35UCAS1229705-06-9ChEMBLCHEMBL2402737PubChem53358942
Structure
InChIKeyTVTXCJFHQKSQQM-LJQIRTBHSA-NSMILESCOC1=CC(=CC=C1NC(=O)[C@@H]1N[C@@H](CC(C)(C)C)[C@@](C#N)([C@H]1C1=CC=CC(Cl)=C1F)C1=CC=C(Cl)C=C1F)C(O)=O
Targets
Q15303ERBB4Q00987MDM2

What you can answer from here — as of January 29, 2025

2Protein targetsEach mapped to UniProt, with action and pharmacological action
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16Clinical trialsPhase, status and sponsor resolved per trial
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2+ReferencesStructured and connected to the statements they support
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Which drugs share a target with Idasanutlin, and which of those have an active Phase 3 trial?

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