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Displaying results 2491 - 2500 of 10000 in total
  1. Drug

    CM4620

    go.drugbank.com/drugs/DB16466
    Investigational

    CM4620 (Zegocractin), is under investigation in multiple clinical trials, including NCT04195347 (pancreatitis due to asparaginase), NCT03709342 (PK/PD study in acute pancreatitis), NCT03401190 and NCT04681066 … (pancreatitis and SIRS), and NCT04661540 (critical COVID-19 pneumonia).

    Categories: Heterocyclic Compounds, 1-Ring, Experimental Unapproved Treatments for COVID-19Synonyms: N-(5-(6-CHLORO-2,2-DIFLUOROBENZO(D)(1,3)DIOXOL-5-YL)PYRAZIN-2-YL)-2-FLUORO-6-METHYLBENZAMIDE, BENZAMIDE, N-(5-(6-CHLORO-2,2-DIFLUORO-1,3-BENZODIOXOL-5-YL)-2-PYRAZINYL)-2-FLUORO-6-METHYL-
  2. Drug

    Dihydrostreptomycin

    go.drugbank.com/drugs/DB11512
    ApprovedVet approvedWithdrawn

    Dihydrostreptomycin is an aminoglycoside antibiotic. In humans, the use of dihydrostreptomycin has been associated with ototoxicity.

    Synonyms: N,N'''-[(1R,2R,3S,4R,5R,6S)-4-({5-deoxy-2-O-[2-deoxy-2-(methylamino)-a-L-glucopyranosyl]-3-C-(hydroxymethyl)-a-L-lyxofuranosyl}oxy)-2,5,6-trihydroxycyclohexane-1,3-diyl]diguanidine, N,N'''-[(1R,2R,3S,4R,5R,6S)-4-({5-deoxy-2-O-[2-deoxy-2-(methylamino)-α-L-glucopyranosyl]-3-C-(hydroxymethyl)-α-L-lyxofuranosyl}oxy)-2,5,6-trihydroxycyclohexane-1,3-diyl]diguanidine
  3. Drug

    N-[4-([(2-Amino-4-oxo-1,4-dihydropyrido[3,2-d]pyrimidin-6-yl)methyl]{(2E)-3-[4-carbamoyl-1-(5-O-phosphono-beta-D-ribofuranosyl)-1H-imidazol-5-yl]-2-propenoyl}amino)benzoyl]-L-glutamic acid

    go.drugbank.com/drugs/DB04057
    Experimental

    Synonyms: N-[4-([(2-Amino-4-oxo-1,4-dihydropyrido[3,2-d]pyrimidin-6-yl)methyl]{(2E)-3-[4-carbamoyl-1-(5-O-phosphono-beta-D-ribofuranosyl)-1H-imidazol-5-yl]-2-propenoyl}amino)benzoyl]-L-glutamic acid, β-DADF, MSA, multisubstrate adduct inhibitor
  4. Drug

    Plumbagin

    go.drugbank.com/drugs/DB17048
    Investigational

    Plumbagin is a compound investigated for its anticancer activity. It has been found that it inactivates the Akt/NF-kB, MMP-9 and VEGF pathways.[A253102]

    Categories: Compounds used in a research, industrial, or household settingSynonyms: 5-hydroxy-2-methyl-1,4-naphthalenedione
  5. Drug

    Iodothiouracil

    go.drugbank.com/drugs/DB20066
    Experimental

    Iodothiouracil has a monoisotopic molecular weight of 253.9 Da. … Iodothiouracil is a small molecule drug. The usage of the INN stem '-racil' in the name indicates that Iodothiouracil is a uracil type antineoplastic.

    Categories: Heterocyclic Compounds, 1-RingSynonyms: 5-iodo-2-thiouracil
  6. Drug

    Edralbrutinib

    go.drugbank.com/drugs/DB18095
    Investigational

    Edralbrutinib is an orally available small molecule inhibitor of Bruton's tyrosine kinase.

    Synonyms: 4-amino-3-(4-(2,6-difluorophenoxy)phenyl)-1,6-dihydro-1-((3r)-1-(1-oxo-2-butyn-1-yl)-3-pyrrolidinyl)-7h-pyrrolo(2,3-d)pyridazin-7-one, 7h-pyrrolo(2,3-d)pyridazin-7-one, 4-amino-3-(4-(2,6-difluorophenoxy)phenyl)-1,6-dihydro-1-((3r)-1-(1-oxo-2-butyn-1-yl)-3-pyrrolidinyl)-
  7. Drug

    Nifurmerone

    go.drugbank.com/drugs/DB20664
    Experimental

    Nifurmerone is a small molecule drug. The usage of the INN stem 'nifur-' in the name indicates that Nifurmerone is a 5-nitrofuran derivative. … Nifurmerone has a monoisotopic molecular weight of 188.98 Da.

    Synonyms: 5-nitro-2-furyl ketone
  8. Drug

    Ginsenoside Rd

    go.drugbank.com/drugs/DB19256
    Investigational

    Ginsenoside Rd is under investigation in clinical trial NCT00815763 (Efficacy and Safety of Ginsenoside-rd for Acute Ischemic Stroke).

    Synonyms: -d-glucopyranoside, (3.beta.,12.beta.)-20-(.beta.-d-glucopyranosyloxy)-12-hydroxydammar-24-en-3-yl 2-o-.beta.-d-glucopyranosyl-
  9. Drug

    (11S)-8-CHLORO-11-[1-(METHYLSULFONYL)PIPERIDIN-4-YL]-6-PIPERAZIN-1-YL-11H-BENZO[5,6]CYCLOHEPTA[1,2-B]PYRIDINE

    go.drugbank.com/drugs/DB07216
    Experimental

    Synonyms: (11S)-8-CHLORO-11-[1-(METHYLSULFONYL)PIPERIDIN-4-YL]-6-PIPERAZIN-1-YL-11H-BENZO[5,6]CYCLOHEPTA[1,2-B]PYRIDINE
  10. Drug

    3-(1H-indol-3-yl)-4-(1-{2-[(2S)-1-methylpyrrolidinyl]ethyl}-1H-indol-3-yl)-1H-pyrrole-2,5-dione

    go.drugbank.com/drugs/DB07456
    Experimental

    Synonyms: 3-(1H-indol-3-yl)-4-(1-{2-[(2S)-1-methylpyrrolidinyl]ethyl}-1H-indol-3-yl)-1H-pyrrole-2,5-dione