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Technetium Tc-99m medronate
go.drugbank.com/drugs/DB09138ApprovedInvestigationalLike other bisphosphonates used in the treatment of osteoporosis, medronic acid binds to the hydroxyapatite crystals within bone, and in this way localizes the drug to bone for delineation of areas of … Following intravenous injection, single photon emission computed tomography (SPECT) is performed to detect the gamma ray emmitted by the decay of Technetium-99m to Technetium-99.
Categories: Indicators and Reagents, Compounds used in a research, industrial, or household settingSynonyms: AN-MDPBelumosudil
go.drugbank.com/drugs/DB16703ApprovedInvestigationalimmune dysregulation by shifting the balance between Th17 cells and T-regulatory cells, thereby dampening the inflammatory cascade that can occasionally be fatal. … [L34754] In July 2022, Belumosudil was approved by Health Canada under the brand name RHOLISTIQ to treat the same condition in adult and pediatric patients 12 years or older.[L42925]
Categories: Antineoplastic and Immunomodulating AgentsNiraparib
go.drugbank.com/drugs/DB11793ApprovedInvestigationalNiraparib is an orally active poly (ADP-ribose) polymerase (PARP) inhibitor. By blocking the enzymes responsible for DNA repair, niraparib induces cytotoxicity in cancer cells. … [L43277] Niraparib was approved by the European Commission on November 16, 2017 [L43742] and by Health Canada on June 27, 2019.
Categories: niraparib and abiraterone, Antineoplastic and Immunomodulating AgentsP-type Ca(2+) transporter
go.drugbank.com/bio_entities/BE0009164TargetPlasmodium falciparumPolypeptides: P-type Ca(2+) transporterSynonyms: Sarcoplasmic and endoplasmic reticulum Ca-ATPase, P-type Ca2+-transporting ATPaseCaplacizumab
go.drugbank.com/drugs/DB06081ApprovedInvestigationalCaplacizumab was developed by Ablynx, a Sanofi company and FDA approved on February 6, 2019,[L5302] and approved previously by the EU in October 2018 as a combination therapy with plasma exchange and immunosuppression … [A174634]In December 2025, the FDA expanded this indication to include pediatric patients aged 12 years and older with aTTP, in the same combination regimen.[L54958,L54963]
Categories: Amino Acids, Peptides, and Proteins, Blood and Blood Forming OrgansDimethicone 410
go.drugbank.com/drugs/DB14005Approved[L1769] It is currently recognized by the FDA as a skin protectant OTC ingredient for human use in a concentration of 1-30%. … Dimethicone is a silicone-based polymer used as a moisturizer in different skin OTC products.[A32462] It is formed by repeated polymeric units of -(CH3)2SiO- with a terminal trimethyl siloxy unit.
Strontium ranelate
go.drugbank.com/drugs/DB09267ApprovedWithdrawnThis agent presents an atypical mechanism of action in which it increases deposition of new bone by osteoblasts and, simultaneously, reduces the resorption of bone by osteoclasts. … Available for prescription use for a time in some parts of the world as Protelos (strontium ranelate) 2 g granules for oral suspension by Servier, it was ultimately discontinued in 2016-2017 owing to an
Mixtures: STRODAY D3 2G/800 IU SAŞE , 28 SAŞE, FULLBONE D3 2 G/800 IU EFERVESAN TABLET, 30 ADETCategories: strontium ranelate and colecalciferol, Drugs Affecting Bone Structure and MineralizationTegaserod
go.drugbank.com/drugs/DB01079ApprovedWithdrawn[L5918,F4229] Zelnorm (tegaserod) by Sloan Pharma subsequently gained re-approval in April of 2019.[L5918] Nevertheless, tegaserod remains un-approved in certain regions. … mechanism of action of acting on serotonin-4 (5-HT(4)) receptors in smooth muscle cells and in the gastrointestinal wall to facilitate actions like esophageal relaxation, peristaltic gut movement, and
Categories: Alimentary Tract and MetabolismTriethylhexanoin
go.drugbank.com/drugs/DB14102InvestigationalTriethylhexanoin is an ingredient of cosmetic products as a fragrant solvent.
Categories: Compounds used in a research, industrial, or household settingProducts: 3ce Lip Color 906 Bite ItBalsam of Peru
go.drugbank.com/drugs/DB11482ApprovedNutraceuticalVet approved[L2879] By Health Canada, the balsam of Peru is approved by the use of over-the-counter combination products and it is currently approved in veterinary products. … [L1113] By the EMA, the balsam of Peru is approved and categorized under the herbal medicine products.[F121]
Mixtures: PainAway with natural peppermint and Balsam Peru, Stroke II SynergyCategories: Compounds used in a research, industrial, or household setting