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Talc
go.drugbank.com/drugs/DB09511ApprovedInvestigationalTalc is a mineral composed primarily of magnesium, silicon and oxygen. … It is a substance often found in cosmetic and personal hygiene products including baby powder, adult body powders and facial powders.
Categories: Compounds used in a research, industrial, or household settingEnfuvirtide
go.drugbank.com/drugs/DB00109ApprovedInvestigationalEnfuvirtide is a 36 amino acid biomimetic peptide that is structurally similar to the HIV proteins that are responsible for the fusion of the virus to cell membranes and subsequent intracellular uptake … The first agent in the novel class of antiretroviral drugs called HIV fusion inhibitors, enfuvirtide works by inhibiting HIV-1 fusion with CD4 cells.
Vanoxerine
go.drugbank.com/drugs/DB03701Investigational[A37914] Although several studies have suggested that the profile of vanoxerine is safer than that of cocaine,[A19824,A248550] other studies have found that vanoxerine has at least moderate potential to … [A19824] Vanoxerine was later evaluated as a potential treatment for cocaine addiction due to its ability to block dopamine reuptake with a slower dissociation rate than cocaine.
Nusinersen
go.drugbank.com/drugs/DB13161ApprovedInvestigationalFDA in December, 2016 as Spinraza for the treatment of children and adults with spinal muscular atrophy (SMA). It is adminstrated as direct intrathecal injection. … An antisense oligonucleotide that induces survival motor neuron (SMN) protein expression, it was approved by the U.S.
Frovatriptan
go.drugbank.com/drugs/DB00998ApprovedFrovatriptan is a triptan drug developed by Vernalis for the treatment of migraine headaches, in particular those associated with menstruation. … Frovatriptan causes vasoconstriction of arteries and veins that supply blood to the head.
Categories: Serotonergic Drugs Shown to Increase Risk of Serotonin SyndromeRozanolixizumab
go.drugbank.com/drugs/DB14919ApprovedInvestigational[A260192] As a result, the main clinical manifestation of myasthenia gravis is easily fatigable or persistent muscle weakness. … Rozonolixizumab itself is an IgG4P, an inactive isotype, to reduce the likelihood of unwanted chain exchange.
Indium In-111 pentetreotide
go.drugbank.com/drugs/DB11835ApprovedIndium In 111 pentetreotide (Octreoscan) has been used in trials studying the diagnostic of SARCOIDOSIS, Solid Tumors, and cushing syndrome.
Mixtures: Kit for the Preparation of Indium In 111 PentetreotideNetupitant
go.drugbank.com/drugs/DB09048ApprovedInvestigationalNetupitant is an antiemitic drug approved by the FDA in October 2014 for use in combination with palonosetron for the prevention of acute and delayed vomiting and nausea associated with cancer chemotherapy … Netupitant is a neurokinin 1 receptor antagonist. The combination drug is marketed by Eisai Inc. and Helsinn Therapeutics (U.S.) Inc. under the brand Akynzeo.
Caspofungin
go.drugbank.com/drugs/DB00520ApprovedInvestigationalIt shows activity against infections with Aspergillus and Candida, and works by inhibiting β(1,3)-D-Glucan of the fungal cell wall. … Caspofungin (brand name Cancidas worldwide) is an antifungal drug and the first member of a new drug class called the echinocandins, as coined by Merck & Co., Inc.
Products: CASPOFUNGINA 50 MG/VIAL POLVO PARA RECONSTITUIR A SOLUCION INYECTABLE, CASPOVITAE® 50 MG POLVO LIOFILIZADO PARA RECONSTITUIR A SOLUCION INYECTABLEMecasermin rinfabate
go.drugbank.com/drugs/DB14751ApprovedInvestigationalIn 2007 Insmed withdrew their application for a marketing authorization with The European Medicines Agency[F4075]. … The binding of IGF-1 to IGFBP-3 is said to extend the half life and reduce the clearance of IGF-1 in patients with growth hormone resistant syndromes and low levels of IGFBP-3 though this may represent