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Displaying results 2531 - 2540 of 10000 in total
  1. Drug

    JNJ-39758979

    go.drugbank.com/drugs/DB18899
    Investigational

    JNJ-39758979 is under investigation in clinical trial NCT01480388 (A Dose Range Finding Study of JNJ-39758979 in Patients With Active Rheumatoid Arthritis Currently Treated With Methotrexate).

    Categories: Heterocyclic Compounds, 1-RingSynonyms: 2-PYRIMIDINAMINE, 4-((3R)-3-AMINO-1-PYRROLIDINYL)-6-(1-METHYLETHYL)-
  2. Drug

    Indoximod

    go.drugbank.com/drugs/DB12827
    Investigational

    Indoximod has been used in trials studying the treatment of Glioma, Melanoma, Ependymoma, Gliosarcoma, and Lung Cancer, among others.

    Synonyms: 1-methyl-D-tryptophan, D-1-methyltryptophan
  3. Drug

    Fimasartan

    go.drugbank.com/drugs/DB09279
    Investigational

    It has been found to be safe when administered with hydrochlorothiazide (a diuretic) in clinical trials. … Fimasartan is an angiotensin II receptor antagonist (ARB) drug employed in the treatment of both hypertension and heart failure.

    Mixtures: DI-ARAHKOR, ARAHKOR DUOCategories: Heterocyclic Compounds, 1-Ring, Agents Acting on the Renin-Angiotensin System
  4. Drug

    (2S)-({(5Z)-5-[(5-Ethyl-2-furyl)methylene]-4-oxo-4,5-dihydro-1,3-thiazol-2-yl}amino)(4-fluorophenyl)acetic acid

    go.drugbank.com/drugs/DB08706
    Experimental

    Synonyms: (2S)-({(5Z)-5-[(5-Ethyl-2-furyl)methylene]-4-oxo-4,5-dihydro-1,3-thiazol-2-yl}amino)(4-fluorophenyl)acetic acid
  5. Drug

    (2R)-2-[(1R)-1-[[(2Z)-2-(2-Amino-1,3-thiazol-4-yl)-2-methoxyiminoacetyl]amino]-2-oxoethyl]-5-methylidene-2H-1,3-thiazine-4-carboxylic acid

    go.drugbank.com/drugs/DB08375
    Experimental

    Synonyms: (2R)-2-[(1R)-1-[[(2Z)-2-(2-Amino-1,3-thiazol-4-yl)-2-methoxyiminoacetyl]amino]-2-oxoethyl]-5-methylidene-2H-1,3-thiazine-4-carboxylic acid
  6. Drug

    Enisoprost

    go.drugbank.com/drugs/DB19319
    Experimental

    Synonyms: (+/-)-methyl (z)-7-((1r,2r,3r)-3-hydroxy-2-((e)-(4rs)-4-hydroxy-4-methyl-1-octenyl)-5-oxocyclopentyl)-4-heptenoate, Prosta-4,13-dien-1-oic acid, 11,16-dihydroxy-16-methyl-9-oxo-, methyl ester, (4z,11.alpha.,13e)-(+/-)-Categories: Prostaglandins E
  7. Drug

    Candoxatril

    go.drugbank.com/drugs/DB00616
    Experimental

    Candoxatril is the orally-active prodrug of candoxatrilat (UK-73967), a potent neutral endopeptidase (NEP) inhibitor.

    Synonyms: 4-({1-[(S)-2-(indan-5-yloxycarbonyl)-3-(2-methoxy-ethoxy)-propyl]-cyclopentanecarbonyl}-amino)-cyclohexanecarboxylic acid, [4(S)-cis]-4-[[[1-[3-[(2,3-dihydro-1H-Indeb5-yl)oxy]-2-[(2-methoxyethoxy)methyl]-3-oxopropyl]cyclopentyl]carbonyl]amino]cyclohexanecarboxylic acid
  8. Drug

    Ajoene

    go.drugbank.com/drugs/DB17735
    Investigational

    Synonyms: (E, Z)-4,5,9-trithiadodeca-1, 6, 11-triene 9-oxide (Ajoene), 2-propen-1-yl (3-(2-propen-1-ylsulfinyl)-1-propen-1-yl) disulfide
  9. Drug

    Apadamtase alfa

    go.drugbank.com/drugs/DB15164
    ApprovedInvestigational

    [A262076] It may be inherited (congenital TTP; cTTP) or acquired due to autoantibodies (immune-mediated TTP; iTTP), although cTTP accounts for <5% of all cases of TTP. … [A262076] Patients with cTTP have a severe deficiency of a plasma metalloproteinase called ADAMTS13 (a disintegrin and metalloproteinase with a thrombospondin type 1 motif, member 13), which is responsible

    Synonyms: Recombinant disintegrin and metalloprotease with thrombospondin type 1 motifs, rADAMTS-13
  10. Drug

    Esaprazole

    go.drugbank.com/drugs/DB19808
    Experimental

    Esaprazole has a monoisotopic molecular weight of 225.18 Da. … Esaprazole is a small molecule drug. The usage of the INN stem '-prazole' in the name indicates that Esaprazole is a benzimidazole derivative antiulcer medication.

    Categories: Heterocyclic Compounds, 1-RingSynonyms: N-cyclohexyl-1-piperazineacetamide, N-(1-piperazinylacetyl)cyclohexylamine