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JNJ-39758979

This drug entry is a stub and has not been fully annotated. It is scheduled to be annotated soon.

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Data Packages
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Identification

Generic Name
JNJ-39758979
DrugBank Accession Number
DB18899
Background

JNJ-39758979 is under investigation in clinical trial NCT01480388 (A Dose Range Finding Study of JNJ-39758979 in Patients With Active Rheumatoid Arthritis Currently Treated With Methotrexate).

Type
Small Molecule
Groups
Investigational
Structure
3D
Similar Structures
Weight
Average: 221.308
Monoisotopic: 221.164045632
Chemical Formula
C11H19N5
Synonyms
  • 2-PYRIMIDINAMINE, 4-((3R)-3-AMINO-1-PYRROLIDINYL)-6-(1-METHYLETHYL)-
External IDs
  • JNJ 39758979
  • JNJ-39758979
  • JNJ-39758979, (-)-
  • JNJ39758979
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Pharmacology

Indication

Not Available

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Contraindications & Blackbox Warnings
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Pharmacodynamics

Not Available

Mechanism of action
Not Available
Absorption

Not Available

Volume of distribution

Not Available

Protein binding

Not Available

Metabolism
Not Available
Route of elimination

Not Available

Half-life

Not Available

Clearance

Not Available

Adverse Effects
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Toxicity

Not Available

Pathways
Not Available
Pharmacogenomic Effects/ADRs
Not Available

Interactions

Drug Interactions
This information should not be interpreted without the help of a healthcare provider. If you believe you are experiencing an interaction, contact a healthcare provider immediately. The absence of an interaction does not necessarily mean no interactions exist.
Not Available
Food Interactions
Not Available

Categories

Drug Categories
Not Available
Classification
Not classified
Affected organisms
Not Available

Chemical Identifiers

UNII
5RV7T5BNMG
CAS number
1046447-90-8
InChI Key
COOGVHJHSCBOQT-MRVPVSSYSA-N
InChI
InChI=1S/C11H19N5/c1-7(2)9-5-10(15-11(13)14-9)16-4-3-8(12)6-16/h5,7-8H,3-4,6,12H2,1-2H3,(H2,13,14,15)/t8-/m1/s1
IUPAC Name
SMILES
CC(C)C1=CC(=NC(N)=N1)N1CC[C@@H](N)C1

References

General References
Not Available
ChemSpider
34236987
BindingDB
50006789
ChEMBL
CHEMBL3236549
ZINC
ZINC000114197058

Clinical Trials

Clinical Trials
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PhaseStatusPurposeConditionsCountStart DateWhy Stopped100+ additional columns
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2CompletedTreatmentAsthma1somestatusstop reasonjust information to hide
2TerminatedTreatmentAtopic Dermatitis1somestatusstop reasonjust information to hide
2WithdrawnTreatmentActive Rheumatoid Arthritis; Rheumatoid Arthritis1somestatusstop reasonjust information to hide
2WithdrawnTreatmentAsthma1somestatusstop reasonjust information to hide
1CompletedTreatmentRheumatoid Arthritis1somestatusstop reasonjust information to hide

Pharmacoeconomics

Manufacturers
Not Available
Packagers
Not Available
Dosage Forms
Not Available
Prices
Not Available
Patents
Not Available

Properties

State
Not Available
Experimental Properties
Not Available
Predicted Properties
PropertyValueSource
Predicted ADMET Features
Not Available

Spectra

Mass Spec (NIST)
Not Available
Spectra
Not Available
Chromatographic Properties
Collision Cross Sections (CCS)
Not Available

Drug created at June 27, 2024 11:18 / Updated at June 28, 2024 04:46