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Duvoglustat
go.drugbank.com/drugs/DB03206InvestigationalAn alpha-glucosidase inhibitor with antiviral action. Derivatives of deoxynojirimycin may have anti-HIV activity.
Synonyms: 5-amino-1,5-dideoxy-D-glucopyranose, D-1-deoxynojirimycinCategories: Heterocyclic Compounds, 1-RingSitagliptin
go.drugbank.com/drugs/DB01261ApprovedInvestigationalSitagliptin was granted FDA approval on October 16, 2006[L6061]. … Sitagliptin is an oral dipeptidyl peptidase-4 (DPP-4) inhibitor used in conjunction with diet and exercise to improve glycemic control in patients with type 2 diabetes mellitus[FDA label,A2260,A2255,A2256
Mixtures: JANUMET 50 MG/500 MG FILM KAPLI TABLET, 56 ADET, JANUMET 50 MG/850 MG FILM KAPLI TABLET, 56 ADETCategories: Heterocyclic Compounds, 1-Ring, Cytochrome P-450 SubstratesHydrocortisone
go.drugbank.com/drugs/DB00741ApprovedInvestigationalVet approved[L10529,L10532,L10535,L10538,L7772,L7321] It was discovered in the 1930s by Edward Kendall and named Compound F, or 17-hydroxycorticosterone. … [A188420] Hydrocortisone was granted FDA approval on 5 August 1952.[L10574]
Synonyms: Reichstein's substance M, 17-HydroxycorticosteroneInternational brands: Polcort H, Preparation H Hydrocortisone CreamBavdegalutamide
go.drugbank.com/drugs/DB19032InvestigationalBavdegalutamide is under investigation in clinical trial NCT03888612 (Trial of ARV-110 in Patients With Metastatic Castration Resistant Prostate Cancer).
Synonyms: N-((1r,4r)-4-(3-chloro-4-cyanophenoxy)cyclohexyl)-6-(4-((4-(2-(2,6-dioxopiperidin-3-yl)-6-fluoro-1,3-dioxo-2,3-dihydro-1h-isoindol-5-yl)piperazin-1-yl)methyl)piperidin-1-yl)pyridazine-3-carboxamide, 3-pyridazinecarboxamide, n-(trans-4-(3-chloro-4-cyanophenoxy)cyclohexyl)-6-(4-((4-(2-(2,6-dioxo-3-piperidinyl)-6-fluoro-2,3-dihydro-1,3-dioxo-1h-isoindol-5-yl)-1-piperazinyl)methyl)-1-piperidinyl)-Esmolol
go.drugbank.com/drugs/DB00187ApprovedInvestigationalWithdrawnEsmolol, commonly marketed under the trade name Brevibloc, is a cardioselective beta-1 receptor blocker. … It has a rapid onset but short duration of action without causing significant intrinsic sympathomimetic or membrane stabilizing activities at recommended therapeutic doses.
Categories: Adrenergic beta-1 Receptor Antagonists, Cytochrome P-450 SubstratesSynonyms: Methyl 4-(2-hydroxy-3-((1-methylethyl)amino)propoxy)benzenepropanoate, 3-[4-(2-Hydroxy-3-isopropylamino-propoxy)-phenyl]-propionic acid methyl esterBetamethasone
go.drugbank.com/drugs/DB00443ApprovedInvestigationalVet approvedBetamethasone is a long-acting corticosteroid with immunosuppressive and antiinflammatory properties. … [A192444] It can be used topically to manage inflammatory skin conditions such as eczema, and parenterally to manage several disease states including autoimmune disorders.
Mixtures: DİPROSPAN 5 MG + 2 MG / 1 ML ENJEKSİYONLUK SÜSPANSİYON, DİPROSPAN 5 MG + 2 MG / 1 ML ENJEKSİYONLUK SÜSPANSİYONCategories: P-glycoprotein substrates, Cytochrome P-450 SubstratesSodium chloride
go.drugbank.com/drugs/DB09153ApprovedInvestigationalVet approvedSodium chloride, also known as salt, common salt, table salt or halite, is an ionic compound with the chemical formula NaCl, representing a 1:1 ratio of sodium and chloride ions. … It is listed on the World Health Organization Model List of Essential Medicines.
Mixtures: LIBAVIT-K 20 MG AMPUL, 5 ADET, DEXTROSE 10% IN 1/5 STR. SALINEProducts: SERUM SALE 2000 MG/10 ML ENJEKSİYONLUK ÇÖZELTİ, 10 AMPUL, SERUM SALE 2000 MG/10 ML ENJEKSİYONLUK ÇÖZELTİ, 100 AMPULSymmetric dimethylarginine
go.drugbank.com/drugs/DB02302ExperimentalSynonyms: Guanidino-N(1),N(2)-dimethylarginine, NG,N'G-dimethylarginineZuclopenthixol
go.drugbank.com/drugs/DB01624ApprovedInvestigationalKnown drug targets of zuclopenthixol include 5-hydroxytryptamine receptor 2A, D(1B) dopamine receptor, D(2) dopamine receptor, D(1A) dopamine receptor, and alpha-1A adrenergic receptor. … Zuclopenthixol is a thioxanthene-based neuroleptic with therapeutic actions similar to the phenothiazine antipsychotics. It is an antagonist at D1 and D2 dopamine receptors.
Categories: Adrenergic alpha-1 Receptor Antagonists, Serotonin 5-HT2 Receptor AntagonistsSynonyms: (Z)-4-(3-(2-Chlorothioxanthen-9-ylidene)propyl)-1-piperazineethanolTofacitinib
go.drugbank.com/drugs/DB08895ApprovedInvestigationalTofacitinib is an inhibitor of Janus kinases, a group of intracellular enzymes involved in signalling pathways that affect hematopoiesis and immune cell function. … It is approved by the FDA for treatment of moderate to severe rheumatoid arthritis that responds inadequately to methotrexate or in those who are intolerant to methotrexate.
Categories: Heterocyclic Compounds, 1-Ring, Cytochrome P-450 SubstratesProducts: Tositin 10 mg Film Kaplı Tablet, 56 ADET, XELJANZ® XR 11 MG TABLETAS DE LIBERACIÓN MODIFICADA