Sodium chloride
Identification
- Name
- Sodium chloride
- Accession Number
- DB09153
- Description
Sodium chloride, also known as salt, common salt, table salt or halite, is an ionic compound with the chemical formula NaCl, representing a 1:1 ratio of sodium and chloride ions. Sodium chloride is the primary salt in seawater and in the extracellular fluid of many multicellular organisms. It is listed on the World Health Organization Model List of Essential Medicines.
- Type
- Small Molecule
- Groups
- Approved, Vet approved
- Structure
Structure for Sodium chloride (DB09153)
- Weight
- Average: 58.443
Monoisotopic: 57.958622382 - Chemical Formula
- ClNa
- Synonyms
- Cloruro sódico
- Natriumchlorid
- Natrum muriaticum
- External IDs
- B1655
- LS-1700
- NSC-77364
Pharmacology
- Indication
This intravenous solution is indicated for use in adults and pediatric patients as a source of electrolytes and water for hydration. Also, designed for use as a diluent and delivery system for intermittent intravenous administration of compatible drug additives.
- Associated Conditions
- Associated Therapies
- Contraindications & Blackbox Warnings
Learn about our commercial Contraindications & Blackbox Warnings data.
Learn More- Pharmacodynamics
Sodium, the major cation of the extracellular fluid, functions primarily in the control of water distribution, fluid balance, and osmotic pressure of body fluids. Sodium is also associated with chloride and bicarbonate in the regulation of the acid-base equilibrium of body fluid. Chloride, the major extracellular anion, closely follows the metabolism of sodium, and changes in the acid-base balance of the body are reflected by changes in the chloride concentration.
- Mechanism of action
Sodium and chloride — major electrolytes of the fluid compartment outside of cells (i.e., extracellular) — work together to control extracellular volume and blood pressure. Disturbances in sodium concentrations in the extracellular fluid are associated with disorders of water balance.
- Absorption
Absorption of sodium in the small intestine plays an important role in the absorption of chloride, amino acids, glucose, and water. Chloride, in the form of hydrochloric acid (HCl), is also an important component of gastric juice, which aids the digestion and absorption of many nutrients.
- Volume of distribution
The volume of distribution is 0.64 L/kg.
- Protein binding
Sodium is not bound by plasma proteins.
- Metabolism
The salt that is taken in to gastro intestinal tract remains for the most part unabsorbed as the liquid contents pass through the stomach and small bowel. On reaching the colon this salt, together with the water is taken in to the blood. As excesses are absorbed the kidney is constantly excreting sodium chloride, so that the chloride level in the blood and tissues remains fairly constant.Further more, if the chloride intake ceases, the kidney ceases to excrete chlorides. Body maintains an equilibrium retaining the 300gm of salt dissolved in the blood and fluid elements of the tissue dissociated into sodium ions and chloride ions.
- Route of elimination
Substantially excreted by the kidneys. (drugs.com)
- Half-life
17 minutes.
- Clearance
- Not Available
- Adverse Effects
Learn about our commercial Adverse Effects data.
Learn More- Toxicity
The rare inadvertent intravascular administration or rapid intravascular absorption of hypertonic sodium chloride can cause a shift of tissue fluids into the vascular bed, resulting in hypervolemia, electrolyte disturbances, circulatory failure, pulmonary embolism, or augmented hypertension. ( toxnet)
- Affected organisms
- Not Available
- Pathways
- Not Available
- Pharmacogenomic Effects/ADRs
- Not Available
Interactions
- Drug Interactions
- This information should not be interpreted without the help of a healthcare provider. If you believe you are experiencing an interaction, contact a healthcare provider immediately. The absence of an interaction does not necessarily mean no interactions exist.
Drug Interaction Unlock Additional DataLithium carbonate Sodium chloride may increase the excretion rate of Lithium carbonate which could result in a lower serum level and potentially a reduction in efficacy. Lithium citrate Sodium chloride may increase the excretion rate of Lithium citrate which could result in a lower serum level and potentially a reduction in efficacy. Lithium hydroxide Sodium chloride may increase the excretion rate of Lithium hydroxide which could result in a lower serum level and potentially a reduction in efficacy. Tolvaptan The risk or severity of adverse effects can be increased when Sodium chloride is combined with Tolvaptan. Additional Data Available- Extended DescriptionExtended Description
Extended description of the mechanism of action and particular properties of each drug interaction.
Learn more - Severity
- Evidence Level
- ActionAction
An effect category for each drug interaction. Know how this interaction affects the subject drug.
Learn more
- Food Interactions
- No interactions found.
Products
- Active Moieties
Name Kind UNII CAS InChI Key Sodium cation ionic LYR4M0NH37 17341-25-2 FKNQFGJONOIPTF-UHFFFAOYSA-N Chloride ion ionic Q32ZN48698 16887-00-6 VEXZGXHMUGYJMC-UHFFFAOYSA-M - Brand Name Prescription Products
Name Dosage Strength Route Labeller Marketing Start Marketing End Region Image Unlock Additional Data0.45% Sodium Chloride Injection USP Solution Intravenous B. Braun Medical Inc. 1993-12-31 Not applicable Canada 
0.9% Sodium Chloride Injection, solution 900 mg/100mL Intravenous HF Acquisition Co LLC, DBA HealthFirst 2020-05-21 Not applicable US 
0.9% Sodium Chloride Injection, solution 9 mg/1mL Intramuscular; Intravenous; Subcutaneous HF Acquisition Co LLC, DBA HealthFirst 2019-07-18 Not applicable US 0.9% Sodium Chloride Injection, solution 900 mg/100mL Intravenous HF Acquisition Co LLC, DBA HealthFirst 2020-04-07 Not applicable US 0.9% Sodium Chloride Irrigant 900 mg/100mL Irrigation HF Acquisition Co LLC, DBA HealthFirst 2018-10-18 Not applicable US 0.9% Sodium Chloride Injection, solution 900 mg/100mL Intravenous Sc Infomed Fluids Srl 2017-04-24 2017-04-24 US 0.9% Sodium Chloride Injection, solution 900 mg/100mL Intravenous HF Acquisition Co LLC, DBA HealthFirst 2018-10-18 Not applicable US 0.9% Sodium Chloride Injection, solution 900 mg/100mL Intravenous HF Acquisition Co LLC, DBA HealthFirst 2018-10-16 Not applicable US 0.9% Sodium Chloride Injection, solution 900 mg/100mL Intravenous HF Acquisition Co LLC, DBA HealthFirst 2020-04-07 Not applicable US 0.9% Sodium Chloride Injection USP Solution Intramuscular; Intravenous; Subcutaneous Omega Laboratories Ltd 1977-12-31 Not applicable Canada Additional Data Available- Application NumberApplication Number
A unique ID assigned by the FDA when a product is submitted for approval by the labeller.
Learn more - Product CodeProduct Code
A governmentally-recognized ID which uniquely identifies the product within its regulatory market.
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- Generic Prescription Products
Name Dosage Strength Route Labeller Marketing Start Marketing End Region Image Unlock Additional Data3% Sodium Chloride Injection, solution 3 g/100mL Intravenous Becton Dickinson and Company 2020-02-28 Not applicable US Amphenol-40 Injection, solution 9 mg/1mL Intramuscular; Intravenous; Subcutaneous It3 Medical Llc 2017-03-01 Not applicable US Bacteriostatic Sodium Chloride Injection 9 mg/1mL Intramuscular; Intravenous; Subcutaneous Fresenius Kabi USA, LLC 2000-08-08 Not applicable US Bacteriostatic Sodium Chloride Injection 9 mg/1mL Intramuscular; Intravenous; Subcutaneous Cardinal Health 2000-08-08 2016-03-31 US Corvatrol 0.9% Injection 9 mg/1mL Intramuscular; Intravenous; Subcutaneous It3 Medical Llc 2017-03-01 Not applicable US HAEMONETICS 0.9 % Sodium Chloride Solution 900 mg/100mL Extracorporeal Haemonetics Corporation 2013-01-07 Not applicable US Sodium Chloride Injection, solution 450 mg/100mL Intravenous Becton Dickinson and Company 2018-07-23 Not applicable US Sodium Chloride Injection, solution 9 g/1mL Intravenous Nextgen Pharmaceuticals LLC 2020-07-01 Not applicable US Sodium Chloride Injection 900 mg/100mL Intravenous Fresenius Medical Care North America 2007-04-12 Not applicable US Sodium Chloride Injection 9 mg/1mL Intramuscular; Intravenous; Subcutaneous West-ward Pharmaceutical Corp. 2013-09-24 2014-08-12 US Additional Data Available- Application NumberApplication Number
A unique ID assigned by the FDA when a product is submitted for approval by the labeller.
Learn more - Product CodeProduct Code
A governmentally-recognized ID which uniquely identifies the product within its regulatory market.
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- Over the Counter Products
Name Dosage Strength Route Labeller Marketing Start Marketing End Region Image Unlock Additional DataAltachlore Sodium Chloride Hypertonicity Solution / drops 50 mg/1mL Ophthalmic Altaire Pharmaceuticals Inc. 2002-09-24 Not applicable US Ancient Secrets Breathe Again Aerosol, spray 20 mg/100mL Nasal Lotus Brands, Inc. 2011-08-15 Not applicable US Ancient Secrets Breathe Again Childrens Aerosol, spray 20 mg/100mL Nasal Lotus Brands, Inc. 2011-08-15 2015-06-01 US Aqua Maris Baby Liquid 11.25 mg/1mL Nasal Jgl North America Llc 2010-07-08 Not applicable US Aqua Maris Ear Spray 11.25 mg/1mL Auricular (otic) Jgl North America Llc 2009-10-29 Not applicable US Aqua Maris Isotonised Liquid 11.25 mg/1mL Nasal Jgl North America Llc 2001-12-28 Not applicable US Aqua Maris Throat Spray 37.5 mg/1mL Oral Jgl North America Llc 2005-04-20 Not applicable US Athomer Spray 0.9 g/100mL Nasal PHARMACOSMETIC-DIAFARM 2013-01-14 Not applicable US Athomer baby Spray 0.9 g/100mL Nasal PHARMACOSMETIC-DIAFARM 2013-01-14 Not applicable US Athomer mini Spray 0.9 g/100mL Nasal PHARMACOSMETIC-DIAFARM 2013-01-14 Not applicable US Additional Data Available- Application NumberApplication Number
A unique ID assigned by the FDA when a product is submitted for approval by the labeller.
Learn more - Product CodeProduct Code
A governmentally-recognized ID which uniquely identifies the product within its regulatory market.
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- Mixture Products
Name Ingredients Dosage Route Labeller Marketing Start Marketing End Region Image (20 Mmol/l) Potassium Chloride In 3.3% Dextrose and 0.3% Sodium Chloride Injection USP Sodium chloride (300 mg) + Dextrose, unspecified form (3.3 g) + Potassium chloride (150 mg) Solution Intravenous Baxter Laboratories 1978-12-31 Not applicable Canada (20 Mmol/l) Potassium Chloride In 5% Dextrose and 0.9% Sodium Chloride Injection USP Sodium chloride (900 mg) + Dextrose, unspecified form (5 g) + Potassium chloride (150 mg) Solution Intravenous Baxter Laboratories 1990-12-31 Not applicable Canada (20mmol/l) Potassium Chloride In 0.9% Sodium Chloride Injection USP Sodium chloride (900 mg) + Potassium chloride (150 mg) Solution Intravenous Baxter Laboratories 1989-12-31 Not applicable Canada (20mmol/l) Potassium Chloride In 5% Dextrose and 0.2% Sodium Chloride Injection USP Sodium chloride (200 mg) + Dextrose, unspecified form (5 g) + Potassium chloride (150 mg) Solution Intravenous Baxter Laboratories 1989-12-31 2016-07-15 Canada (20mmol/l) Potassium Chloride In 5% Dextrose and 0.45% Sodium Chloride Injection USP Sodium chloride (450 mg) + Dextrose, unspecified form (5 g) + Potassium chloride (150 mg) Solution Intravenous Baxter Laboratories 1989-12-31 Not applicable Canada (40 Mmol/l) Potassium Chloride In 0.9% Sodium Chloride Injection USP Sodium chloride (900 mg) + Potassium chloride (300 mg) Liquid Intravenous Baxter Laboratories 1989-12-31 Not applicable Canada (40 Mmols/l) Potassium Chloride In Lactated Ringer's Injection USP Sodium chloride (600 mg) + Calcium chloride (20 mg) + Sodium lactate (310 mg) + Potassium chloride (328 mg) Solution Intravenous Baxter Laboratories 2002-12-11 2016-07-15 Canada (40mmol/l) Potassium Chloride In 3.3% Dextrose and 0.3% Sodium Chloride Injection USP Sodium chloride (300 mg) + Dextrose, unspecified form (3.3 g) + Potassium chloride (300 mg) Solution Intravenous Baxter Laboratories 1978-12-31 Not applicable Canada (40mmol/l)potassium Chloride In 5% Dextrose and 0.45% Sodium Chloride Injection USP Sodium chloride (450 mg) + Dextrose, unspecified form (5 g) + Potassium chloride (300 mg) Solution Intravenous Baxter Laboratories 1989-12-31 Not applicable Canada 0.15% Potassium Chloride In 3.3% Dextrose and 0.30% Sodium Chloride Injection Sodium chloride (300 mg) + Dextrose, unspecified form (3.3 g) + Potassium chloride (150 mg) Solution Intravenous B. Braun Medical Inc. 1992-12-31 Not applicable Canada - Unapproved/Other Products
Name Ingredients Dosage Route Labeller Marketing Start Marketing End Region Image 0.9% Sodium Chloride Sodium chloride (900 mg/100mL) Injection, solution Intravenous Sc Infomed Fluids Srl 2017-04-24 2017-04-24 US 4381 First Aid Kit Sodium chloride (0.9 g/100mL) + Ammonia (0.045 g/0.3mL) + Bacitracin zinc (400 [iU]/1g) + Benzalkonium chloride (1.3 mg/1mL) + Ethanol (62 mL/100mL) + Hydrocortisone acetate (1 g/100g) + Hydrocortisone acetate (1 g/100g) + Isopropyl alcohol (0.7 mL/1mL) + Neomycin sulfate (3.5 mg/1g) + Polymyxin B sulfate (5000 [iU]/1g) + Water (98.6 mL/100mL) Kit Irrigation; Ophthalmic; Respiratory (inhalation); Topical Honeywell Safety Products USA, Inc. 2018-09-13 Not applicable US 4382 First Aid Kit Sodium chloride (0.9 g/100mL) + Ammonia (0.045 g/0.3mL) + Bacitracin zinc (400 [iU]/1g) + Benzalkonium chloride (1.3 mg/1mL) + Ethanol (62 mL/100mL) + Hydrocortisone acetate (1 g/100g) + Hydrocortisone acetate (1 g/100g) + Isopropyl alcohol (0.7 mL/1mL) + Neomycin sulfate (3.5 mg/1g) + Polymyxin B sulfate (5000 [iU]/1g) + Water (98.6 mL/100mL) Kit Irrigation; Ophthalmic; Respiratory (inhalation); Topical Honeywell Safety Products USA, Inc. 2018-09-13 Not applicable US 4383 First Aid Kit Sodium chloride (0.9 g/100mL) + Bacitracin zinc (400 [iU]/1g) + Benzalkonium chloride (1.3 mg/1mL) + Ethanol (62 mL/100mL) + Hydrocortisone acetate (1 g/100g) + Hydrocortisone acetate (1 g/100g) + Isopropyl alcohol (0.7 mL/1mL) + Neomycin sulfate (3.5 mg/1g) + Polymyxin B sulfate (5000 [iU]/1g) + Water (98.6 mL/100mL) Kit Irrigation; Ophthalmic; Topical Honeywell Safety Products USA, Inc. 2018-09-13 Not applicable US 4384 First Aid Kit Sodium chloride (0.9 g/100mL) + Bacitracin zinc (400 [iU]/1g) + Benzalkonium chloride (1.3 mg/1mL) + Ethanol (62 mL/100mL) + Hydrocortisone acetate (1 g/100g) + Hydrocortisone acetate (1 g/100g) + Isopropyl alcohol (0.7 mL/1mL) + Neomycin sulfate (3.5 mg/1g) + Polymyxin B sulfate (5000 [iU]/1g) + Water (98.6 mL/100mL) Kit Irrigation; Ophthalmic; Topical Honeywell Safety Products USA, Inc. 2018-09-13 Not applicable US 4385 First Aid Kit Sodium chloride (0.9 g/100mL) + Ethanol (665 mL/1L) + Isopropyl alcohol (0.7 mL/1mL) + Povidone-iodine (10 mg/1mL) + Water (98.6 mL/100mL) Irrigation; Ophthalmic; Topical Honeywell Safety Products USA, Inc. 2018-09-13 Not applicable US 4386 First Aid Kit Sodium chloride (0.9 g/100mL) + Ethanol (665 mL/1L) + Isopropyl alcohol (0.7 mL/1mL) + Povidone-iodine (10 mg/1mL) + Water (98.6 mL/100mL) Irrigation; Ophthalmic; Topical Honeywell Safety Products USA, Inc. 2018-09-13 Not applicable US 4387 First Aid Kit Sodium chloride (0.9 g/100mL) + Acetylsalicylic acid (325 mg/1) + Ammonia (0.045 g/0.3mL) + Bacitracin zinc (400 [iU]/1g) + Benzalkonium chloride (1.3 mg/1mL) + Ethanol (665 mL/1L) + Isopropyl alcohol (0.7 mL/1mL) + Neomycin sulfate (3.5 mg/1g) + Polymyxin B sulfate (5000 [iU]/1g) + Povidone-iodine (10 mg/1mL) Irrigation; Oral; Respiratory (inhalation); Topical Honeywell Safety Products USA, Inc. 2018-09-13 Not applicable US 4388 First Aid Kit Sodium chloride (0.9 g/100mL) + Acetylsalicylic acid (325 mg/1) + Ammonia (0.045 g/0.3mL) + Bacitracin zinc (400 [iU]/1g) + Benzalkonium chloride (1.3 mg/1mL) + Ethanol (665 mL/1L) + Isopropyl alcohol (0.7 mL/1mL) + Neomycin sulfate (3.5 mg/1g) + Polymyxin B sulfate (5000 [iU]/1g) + Povidone-iodine (10 mg/1mL) + Water (98.6 mL/100mL) Irrigation; Ophthalmic; Oral; Respiratory (inhalation); Topical Honeywell Safety Products USA, Inc. 2018-09-13 Not applicable US 4393 First Aid Kit Sodium chloride (0.9 g/100mL) + Ammonia (0.045 g/0.3mL) + Bacitracin zinc (400 [iU]/1g) + Benzalkonium chloride (1.3 mg/1mL) + Ethanol (62 mL/100mL) + Hydrocortisone acetate (1 g/100g) + Hydrocortisone acetate (1 g/100g) + Isopropyl alcohol (0.7 mL/1mL) + Neomycin sulfate (3.5 mg/1g) + Polymyxin B sulfate (5000 [iU]/1g) + Water (98.6 mL/100mL) Irrigation; Ophthalmic; Respiratory (inhalation); Topical Honeywell Safety Products USA, Inc. 2018-09-13 Not applicable US
Categories
- ATC Codes
- B05XA03 — Sodium chloride
- B05XA — Electrolyte solutions
- B05X — I.V. SOLUTION ADDITIVES
- B05 — BLOOD SUBSTITUTES AND PERFUSION SOLUTIONS
- B — BLOOD AND BLOOD FORMING ORGANS
- B05CB — Salt solutions
- B05C — IRRIGATING SOLUTIONS
- B05 — BLOOD SUBSTITUTES AND PERFUSION SOLUTIONS
- B — BLOOD AND BLOOD FORMING ORGANS
- Drug Categories
- Acids
- Acids, Noncarboxylic
- Alimentary Tract and Metabolism
- Anions
- Blood and Blood Forming Organs
- Blood Substitutes and Perfusion Solutions
- Chlorides
- Chlorine Compounds
- Diluents
- EENT Drugs, Miscellaneous
- Electrolyte Solutions
- Electrolytes
- I.V. Solution Additives
- Ions
- Irrigating Solutions
- Mineral Supplements
- Miscellaneous Therapeutic Agents
- Other Miscellaneous Therapeutic Agents
- Replacement Preparations
- Respiratory Agents, Miscellaneous
- Salt Solutions
- Sodium
- Sodium Compounds
- Chemical TaxonomyProvided by Classyfire
- Description
- This compound belongs to the class of inorganic compounds known as alkali metal chlorides. These are inorganic compounds in which the largest halogen atom is Chlorine, and the heaviest metal atom is an alkali metal.
- Kingdom
- Inorganic compounds
- Super Class
- Mixed metal/non-metal compounds
- Class
- Alkali metal salts
- Sub Class
- Alkali metal chlorides
- Direct Parent
- Alkali metal chlorides
- Alternative Parents
- Inorganic sodium salts / Inorganic chloride salts
- Substituents
- Alkali metal chloride / Inorganic chloride salt / Inorganic salt / Inorganic sodium salt
- Molecular Framework
- Not Available
- External Descriptors
- inorganic chloride, inorganic sodium salt (CHEBI:26710)
Chemical Identifiers
- UNII
- 451W47IQ8X
- CAS number
- 7647-14-5
- InChI Key
- FAPWRFPIFSIZLT-UHFFFAOYSA-M
- InChI
- InChI=1S/ClH.Na/h1H;/q;+1/p-1
- IUPAC Name
- sodium chloride
- SMILES
- [Na+].[Cl-]
References
- General References
- External Links
- AHFS Codes
- 40:50.00* — Diluents
- 52:92.00 — EENT Drugs, Miscellaneous
- 40:36.00 — Irrigating Solutions
- 92:00.00 — Miscellaneous Therapeutic Agents
- 92:92.00 — Other Miscellaneous Therapeutic Agents
- 40:12.00 — Replacement Preparations
- 48:92.00 — Respiratory Agents, Miscellaneous
- MSDS
- Download (89.8 KB)
Clinical Trials
- Clinical Trials
Phase Status Purpose Conditions Count 4 Active Not Recruiting Treatment Abdominal Wall Hernia / Bowel Diseases / Gastric Diseases / Pancreatic Diseases 1 4 Active Not Recruiting Treatment Blood Loss,Surgical 1 4 Active Not Recruiting Treatment Endothelial Dysfunction / Iron Toxicity / Oxidative Stress / Renal Anemia 1 4 Active Not Recruiting Treatment Impaired kidney function 1 4 Completed Not Available Brain Swelling 1 4 Completed Not Available Colonoscopy 1 4 Completed Not Available Corneal Staining 1 4 Completed Not Available Dry Eyes 1 4 Completed Not Available Transplant, Kidney 1 4 Completed Basic Science Blood Pressures / Overdose of Beta-adrenergic Blocking Drug / Overdose, Drug 1
Pharmacoeconomics
- Manufacturers
- Not Available
- Packagers
- Not Available
- Dosage Forms
Form Route Strength Solution 0.9 % Solution 20 % Solution Intravenous 0.9 % Solution Intravenous 9 % Solution 3 % Solution Intravenous 5 % Injection, solution Intravenous 150 mg/100mL Injection, solution Intravenous 300 mg/100mL Solution Intramuscular; Intravenous; Subcutaneous Solution Intravenous Solution Intravenous 3.3 g/100mL Solution Intravenous 3.75 g/100mL Solution Intravenous 3.2 g/100mL Solution Irrigation Kit Irrigation; Ophthalmic; Respiratory (inhalation); Topical Kit Irrigation; Ophthalmic; Topical Injection, solution 257 mg/1L Solution Topical 200 mcL/100mL Solution Respiratory (inhalation) Kit Intradermal; Subcutaneous Injection, solution Intravenous 2.5 g/500mL Powder, for solution Intraocular Solution Intraocular Aerosol, spray Nasal 20 mg/100mL Liquid Topical Liquid Nasal 11.25 mg/1mL Spray Auricular (otic) 11.25 mg/1mL Spray Oral 37.5 mg/1mL Solution Oral 289.2 mg Spray Nasal 0.9 g/100mL Solution Intraperitoneal 951 mg/L Liquid Respiratory (inhalation) Solution Intraperitoneal 0.1838 g/L Solution Intraperitoneal 0.2573 g/L Solution Ophthalmic Solution Intraocular; Irrigation 1950 mg Powder, for solution Hemodialysis Solution / drops Nasal 0.9 % Solution; spray Nasal 0.9 % Kit; powder, for solution; tablet, delayed release Oral Kit; powder, for solution Hemodialysis Liquid; powder, for solution Subcutaneous Solution Intravenous 3 % Solution 5 % Solution 10 g/L Solution Intravenous 0.64 g/100ml Solution Intravenous 5 g/100ml Solution Intravenous 0.86 g/100ml Solution Intravenous 3 g/L Solution Intravenous 3.1 g/L Injection, solution Intravenous 3.1 g/L Liquid Oral 0.5 g/100mL Solution / drops; suspension / drops Spray Nasal Aerosol, metered Respiratory (inhalation) Solution Irrigation 48 mg/100mL Kit; solution Intraocular Liquid Topical 0.495 g/50mL Liquid Topical 0.99 g/100mL Liquid Topical 2.97 g/300mL Liquid Topical 4.95 g/500mL Powder Topical 60 g/300g Solution Intraperitoneal 0.0003 g Solution Intra-arterial Solution 6340 mg/L Solution Nasal Solution Nasal; Ophthalmic 900 mg/100mL Powder, for solution Nasal 990 mg Swab Topical 0.9 g/100mL Liquid Nasal 6.5 mg/1mL Solution Intravenous 1.491 g Solution Intramuscular; Intravenous; Subcutaneous 9 mg Solution Intrasinal; Nasal 9 mg Solution Intravenous; Irrigation 9 mg Solution Intravenous 20 mEq Solution Intravenous 900 mg Solution Intravenous 1.1688 g Solution Intravenous 0.9 % w/v Solution Intravenous 0.009 g Solution Intravenous 116.9 mg Powder, for solution Nasogastric Powder, for solution Oral 45 g/750mL Solution, concentrate Hemodialysis 99 g Liquid Epidural; Infiltration; Subcutaneous Ointment Topical Solution Topical Solution Ophthalmic 5 % Powder Nasal Solution Irrigation Solution Intraperitoneal Solution Intravenous 6.4 g/L Injection, solution Intravenous 10 g/100mL Solution Intravenous 0.45 g Solution Intravenous 9 mg Liquid Intravenous Injection Intravenous Liquid Topical Injection, solution Intraperitoneal 220 mg Solution Intraperitoneal; Irrigation 18.3 mg Solution Intraperitoneal 18.3 mg Injection, solution Intraperitoneal Liquid Hemodialysis Solution Hemodialysis Injection, solution Intraperitoneal 18.3 mg/100mL Solution 22.7 g/L Solution 13.6 g/L Solution Intraperitoneal 22.7 g/L Solution 38.6 g/L Solution Intraperitoneal 13.6 g/L Solution Intraperitoneal 38.6 g/L Injection Subcutaneous 4.5 mg/0.5mL Liquid Intradermal; Percutaneous; Subcutaneous Liquid Subcutaneous Kit Epidural; Infiltration; Intracaudal; Subcutaneous; Topical Spray Topical Spray Nasal 0.39 mL/60mL Solution / drops Nasal 180 mg/20ml Solution Intravenous 4.21 g/1000ml Kit Epidural; Infiltration; Intra-articular; Intralesional; Intramuscular; Intravenous; Soft tissue; Subcutaneous; Topical Liquid Ophthalmic Solution Oral 12.27 g/100mL Powder Oral Injection, solution Intravenous 3.38 g Solution Intrathecal Injection Intrathecal Powder Oral 52.5 g Solution Rectal 2.5 g Powder, for solution Oral 2.9 g Solution Oral 0.294 g Enema; kit; tablet Rectal Spray Nasal 30 mg/1mL Solution / drops Nasal 500 mg/100mL Solution / drops Nasal 1 g/100mL Kit Epidural; Infiltration Solution Intraperitoneal 0.0257 g Solution 75 g/L Injection, solution Intraperitoneal 25.7 mg/100mL Solution Intraperitoneal 7.5 g/100mL Solution Nasal 0.29 mg/44mL Kit; liquid; powder, for solution Intramuscular; Subcutaneous Liquid; powder, for solution Intramuscular; Subcutaneous Liquid Topical 1.5 g/100mL Injection Intravenous 20 g Solution Intravenous 1.63 g Powder Oral 13.5 g Spray Oral 7.3 mg/50mL Powder, for solution Nasogastric; Oral Solution Extracorporeal 9 g Solution Extracorporeal 900 mg/100mL Solution Extracorporeal Powder, for solution Nasal 1.7 g Solution, concentrate 9 g/1L Solution, concentrate 6.43 g/1L Tablet 600 mg Solution Oral 369 mg Solution Oral 216 mg Solution Oral 30 mg Solution Oral 0.29 g Solution Oral 0.275 g Solution Oral 275 mg Solution Ophthalmic 50 mg Liquid; powder, for solution Intramuscular Solution Intrasinal; Nasal 0.9 g Solution Intravenous 6 % Solution Intravenous 3 g Solution Intravenous 0.31 % Solution Intraperitoneal 7.5 % Solution; spray Nasal 6.25 mg/1mL Liquid Nasal .65 g/100mL Injection Intravenous Liquid Intraperitoneal Solution Hemodialysis; Intraperitoneal Liquid Intravesical Solution Intravenous 0.02 g Liquid Intraocular Solution 0.64 g/100ml Injection Intravenous 3.33 % Solution Intravenous 0.64 % Solution Intravenous 0.03 % Solution Intravenous 0.37 % Solution Intravenous Kit Intravenous; Topical Solution Intravenous 2.5 % Solution Intravenous 3.33 % Solution Intravenous 3.75 % Irrigant Irrigation 0.9 % Injection Intravenous 0.9 % Solution 1000 ml Solution 150 ml Solution 250 ml Solution 50 ml Solution 500 ml Solution 100 ml Solution 3000 ml Liquid Infiltration; Subcutaneous; Topical Tablet Vaginal Solution Intravenous 0.07 g Solution Intravenous 8.6 % Powder, for solution Oral 1.685 g Solution Intravenous 20.475 % Injection, solution Intravenous 30 mg/100mL Solution, for slush Irrigation Solution Intravenous 20 mg Solution Intravenous; Irrigation 0.2 mg Gel Vaginal Solution Intravenous 0.45 % Solution Intravenous 30 mg/mL Injection, solution Intravenous 50 mg/mL Solution Intravenous 50 mg/mL Solution Intravenous 0.3 % Injection, solution Intravenous 3 g/L Injection, solution Intravenous 3.14 g/L Solution / drops Ophthalmic 0.9 % Injection, solution 20 mg/2ml Injection, solution Intravenous 6 g/100mL Powder Oral 3.5 g Powder Oral 5 g/100mL Powder, for solution Oral 13.125 G Powder, for solution Subcutaneous Liquid Buccal Spray Buccal Solution Oral 13.125 g Powder, for solution Oral 6.563 G Kit Oral Solution Oral 100 g Solution Intravenous 0.368 g Solution Ophthalmic 20 mg/1mL Solution Ophthalmic 50 mg/1mL Liquid Intraocular; Ophthalmic Solution Intravenous 117 mg Lotion Topical .65 mL/100mL Capsule 650 mg Injection, solution Intravenous 20 g/100mL Injection, solution 3 g/100mL Solution / drops Ophthalmic 5 g/100mL Solution / drops Nasal 900 mg/100mL Spray Nasal 9.5 mg/1mL Spray Nasal 2600 mg/100mL Solution; spray Nasal 650 mg/100mL Solution; spray Nasal 1 g/100mL Solution Intrasinal; Nasal 1 mL Spray Nasal 3 mL/100mL Spray Nasal 1.2 mg/10mL Injection, solution Parenteral 9 mg/ml Kit; solution Intraocular; Irrigation Injection Intravenous 3.33 g/100ml Injection, solution Intravenous 33.3 g/L Solution Intravenous 55 g/L Solution 0.53 g/100ml Solution Intravenous 0.86 % Injection, solution Intravenous 60 g/1000ml Powder, for solution Oral 118 g Mouthwash 900 mg/100mL Tablet Oral 1 g/1 Injection, solution 900 mg/100mL Solution; spray Nasal 900 mg/100mL Emulsion Intravenous 1.83 g Injection Intravenous 1.03 g Emulsion Intravenous 20 mg Emulsion Intravenous 16 g Injection, solution, concentrate Intravenous Solution Intraperitoneal 510 mg/l Solution Oral Solution Intraocular; Ophthalmic 7.8 mg Lotion Ophthalmic 900 mg/100mL Lotion Ophthalmic 1.24 g/100mL Liquid; mouthwash Solution Auricular (otic) 0.06 g Powder, for solution Oral 59 g Injection, solution Intraperitoneal 32 mg/100mL Solution Oral 108.2 mg Solution Oral 294 mg Solution Oral 29.4 mg Powder, for solution Oral 120 g/129.2g Injection, solution Intravenous 5 % Injection, solution Intravenous 3.75 % Injection, solution Intravenous 10 % Liquid Intradermal; Subcutaneous Solution Intrasinal; Nasal 0.65 g Solution Intraperitoneal 15 g/L Solution Intraperitoneal 25 g/L Solution Intravenous 25 g/L Solution Intraperitoneal 42.5 g/L Irrigant Irrigation Solution Intravenous 368 mg Injection, solution Intravenous Injection, solution Intra-arterial Solution Injection, solution Intravenous 0.45 % Injection, solution Intravenous 0.9 % Solution Intravenous 1 % Solution Intravenous 0.035 % Injection, solution Intravenous 0.03 % Powder, for solution Oral Kit Hemodialysis Solution Hemodialysis; Intravenous Injection, solution 514.5 mg/100mL Injection, solution Intravenous 0.86 g/100mL Solution Parenteral 3 g/100ml Douche Vaginal Powder, for solution Intravenous Powder, for solution Topical 4.5 g Patch Transdermal 0.03 g/1g Kit; liquid; powder Intralesional; Subcutaneous Injection, solution Extracorporeal Liquid; powder, for solution Intravenous; Subcutaneous Solution Irrigation 4.75 mL/100mL Solution Intravenous 0.6 g/100ml Solution Irrigation; Topical 20 mg Injection, solution Intravenous 20 mg/100mL Injection, solution 20 mg/100mL Solution Unknown Powder, for solution Intramuscular; Subcutaneous Spray Nasal 6.5 mg/1mL Spray Oral 6.5 mg/1mL Spray Nasal 2.65 mg/100mL Liquid Nasal Cloth Topical 0.9 g/100mL Gel Nasal Spray Nasal Aerosol Oral Solution Oral 1 g/100mL Powder, for solution Oral 10 g Powder Topical Solution Nasal 20 ml Injection 0.9 % Injection Intravenous 0.09 % Solution Oral 70 mg/1mL Liquid Epidural Powder, for solution Nasal Mouthwash Oral 3 mg/100mL Solution Intravenous 2.25 g Solution Irrigation 0.9 g Solution Intravenous 9 g/l Injection, solution Intravenous 18 MG/2ML Injection, solution Intravenous 180 MG/20ML Injection, solution Intravenous 45 MG/5ML Injection, solution Intravenous 90 MG/10ML Injection, solution Irrigation 0.9 % Solution, concentrate Parenteral 0.117 g/ml Injection, solution Parenteral 0.9 % Injection, solution Parenteral 3 % Injection, solution Parenteral 5 % Injection, solution, concentrate Intravenous 2 mEq/mL Injection, solution, concentrate Intravenous 3 mEq/mL Injection, solution 0.9 % Injection, solution 3 % Injection, solution 5 % Injection, solution, concentrate Intravenous 0.175 g Injection, solution, concentrate Intravenous 1.17 g Injection, solution, concentrate Intravenous 1.75 g Solution Irrigation; Parenteral 0.9 % Solution Parenteral 0.9 % Injection, solution Intravenous 3 % Injection, solution, concentrate Intravenous 3 % Injection, solution, concentrate Intravenous 5 % Solution, concentrate Intravenous 0.117 g/ml Solution, concentrate Intravenous 0.175 g/ml Solution, concentrate Parenteral 0.175 g/ml Powder Hemodialysis Inhalant Respiratory (inhalation) 0.9 mg/100mL Injection Intramuscular; Intravenous; Subcutaneous 0.9 mg/10mL Injection Intramuscular; Intravenous; Subcutaneous 234 mg/1mL Injection Intramuscular; Intravenous; Subcutaneous 9 mg/1mL Injection Intravascular .9 mg/1mL Injection Intravenous 0.45 g/50mL Injection Intravenous 0.9 g/100mL Injection Intravenous 450 mg/50mL Injection Intravenous 450 mg/100mL Injection Intravenous 9 mg/1mL Injection Intravenous 900 mg/1000mL Injection Intravenous 900 mg/100mL Injection, solution Intramuscular; Intravenous; Subcutaneous 234 mg/1mL Injection, solution Intramuscular; Intravenous; Subcutaneous 9 mg/1mL Injection, solution Intravenous 0.45 g/100mL Injection, solution Intravenous 0.9 g/100mL Injection, solution Intravenous 146 mg/1mL Injection, solution Intravenous 234 mg/1mL Injection, solution Intravenous 3 g/100mL Injection, solution Intravenous 4.5 g/1000mL Injection, solution Intravenous 450 mg/50mL Injection, solution Intravenous 450 mg/100mL Injection, solution Intravenous 5 g/100mL Injection, solution Intravenous 9 g/1000mL Injection, solution Intravenous 9 g/1mL Injection, solution Intravenous 9 mg/1mL Injection, solution Intravenous 9 g/1 Injection, solution Intravenous 900 mg/100mL Injection, solution, concentrate Intravenous 2.92 g/20mL Injection, solution, concentrate Intravenous 20 g/100mL Injection, solution, concentrate Intravenous 234 mg/1mL Injection, solution, concentrate Intravenous 5.84 g/40mL Irrigant Irrigation 0.9 g/100mL Irrigant Irrigation 450 mg/100mL Irrigant Irrigation 9 g/1000mL Irrigant Irrigation 900 mg/100mL Ointment Ophthalmic 50 mg/1g Powder, for solution Oral 1 g Solution Intravenous 0.45 g/100mL Solution Intravenous 0.9 g/100mL Solution Respiratory (inhalation) 0.027 mg/3mL Solution / drops Auricular (otic); Ophthalmic 3 g/100mL Solution / drops Ophthalmic 50 mg/1mL Syrup 20 g/100mL Tablet 300 mg Liquid Intravenous Liquid Intravenous; Subcutaneous Solution Injection, solution 20 g/100mL Liquid Intramuscular; Intravenous; Subcutaneous Capsule 800 mg Solution / drops Ophthalmic 3 g/100mL Solution Irrigation 0.9 g/100mL Inhalant Respiratory (inhalation) 9 g/1L Liquid Parenteral Solution Intramuscular; Intraperitoneal; Intravenous; Subcutaneous Solution Intravenous; Subcutaneous Liquid Irrigation; Topical Solution Irrigation 900 mg/100mL Solution Intraperitoneal; Irrigation Solution Intraperitoneal; Irrigation; Topical Tablet Oral 500 mg/1 Powder Oral 1 g Powder Oral 5 g Injection, solution, concentrate Intravenous 3 g/100mL Tablet Irrigation Tablet Oral Solution / drops Ophthalmic 900 mg/100mL Solution Topical 900 mg/100mL Injection, solution, concentrate Intravenous; Subcutaneous 234 mg/1mL Solution Intravenous 0.2 mg Solution Intraperitoneal 25.7 mg Solution Intravenous 6 mg Solution Intravenous 33 mg Solution Intravenous 0.225 g Solution Intravenous 0.9 g Solution Conjunctival; Ophthalmic 12.5 mg Solution Respiratory (inhalation) Mouthwash Oral 4 mcg/100mL Mouthwash Oral 90 mg/100mL Mouthwash Oral 4.4 mg/100mL Kit Intravenous Solution Intraocular; Irrigation 0.39 g Liquid; powder, for solution Intravenous Solution Intrasinal; Nasal 900 mg Solution Parenteral 0.9 g Liquid Oral Tablet Oral Liquid Irrigation Powder, for solution Oral 1.43 g Solution Intravenous 594 mg Solution Irrigation 0.9 % Injection, solution Intravenous 3 g Solution Intravenous; Irrigation 0.62 g/100ml Solution Rectal 15 g/100mL Solution Intraocular; Intravenous 1 mL Solution Topical 30 g/100mL Solution Intravenous 6 g/100mL Injection, solution Intravenous 30 g/500mL Spray Nasal 3 g/100g Kit Nasal Liquid Topical 6.5 mg/1mL Spray Nasal .65 g/100mL Kit Intramuscular; Intravenous Granule, for solution Nasal Capsule 780 mg - Prices
- Not Available
- Patents
Patent Number Pediatric Extension Approved Expires (estimated) Region Unlock Additional DataUS5945449 No 1999-08-31 2017-10-31 US US7300674 No 2007-11-27 2023-03-04 US US6077836 No 2000-06-20 2017-06-20 US US6248726 No 2001-06-19 2018-06-19 US US7291324 No 2007-11-06 2022-10-22 US US7169381 No 2007-01-30 2024-09-01 US US7658914 No 2010-02-09 2024-09-01 US US7084130 No 2006-08-01 2021-11-29 US US9326969 No 2016-05-03 2033-09-10 US US9592252 No 2017-03-14 2032-08-11 US US9707297 No 2017-07-18 2033-09-10 US US8999313 No 2015-04-07 2033-09-10 US US10016504 No 2018-07-10 2033-09-10 US US10646512 No 2012-03-25 2032-03-25 US Additional Data Available- Filed On
Properties
- State
- Solid
- Experimental Properties
- Not Available
- Predicted Properties
Property Value Source Water Solubility 108.0 mg/mL ALOGPS logP 0.06 ALOGPS logP -0.77 ChemAxon logS 0.26 ALOGPS pKa (Strongest Acidic) 3.09 ChemAxon Physiological Charge 1 ChemAxon Hydrogen Acceptor Count 0 ChemAxon Hydrogen Donor Count 0 ChemAxon Polar Surface Area 0 Å2 ChemAxon Rotatable Bond Count 0 ChemAxon Refractivity 0 m3·mol-1 ChemAxon Polarizability 1.78 Å3 ChemAxon Number of Rings 0 ChemAxon Bioavailability 1 ChemAxon Rule of Five Yes ChemAxon Ghose Filter No ChemAxon Veber's Rule Yes ChemAxon MDDR-like Rule No ChemAxon - Predicted ADMET Features
- Not Available
Spectra
- Mass Spec (NIST)
- Not Available
- Spectra
- Not Available
Drug created on October 01, 2015 13:54 / Updated on October 26, 2020 22:41
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