Identification
- Summary
Sodium chloride is an ingredient found in a variety of nutritional products as a source of electrolytes and water.
- Brand Names
- Amphenol-40, As 3, Bi-peglyte, Bicart, Bss, Bss Ophthalmic Solution, Cardioplegic, Citrasate, Clinimix E 2.75/5, Colyte, Corvatrol, Dextrose and Electrolyte No. 75, Dianeal, Dianeal Low Calcium 1.5, Dianeal Pd-2/1.5, Entocort, Extraneal, Eye Stream, Gavilyte-C, Gavilyte-G, Gavilyte-H and Bisacodyl, Gavilyte-N, Golytely, H.E.L.P.bicel, Hemosate Ultra, Hespan, Hizentra, Hyperlyte, Intersol, Isolyte S, Isolyte S pH 7.4, Isoplate, Lactate 1-2-3, Lactated Ringers, Menopur, Moviprep, Muro 128, Naturalyte, Normosol-M, Normosol-R, Nulytely, Nxstage Pureflow, P-Care M, P-Care MG, P-care, P-care X, Peglyte, Phoxillum, Physiolyte, Physioneal 40, Physiosol, Plasma-lyte, Plasma-lyte 148, Plasma-lyte 148 In 5 % Dextrose, Plasma-lyte R, Plasmalyte A, Plegisol, Plenvu, Prismasol, Procalamine 3, Ringers, Sag-M, Sclerodex, Tis-U-sol
- Generic Name
- Sodium chloride
- DrugBank Accession Number
- DB09153
- Background
Sodium chloride, also known as salt, common salt, table salt or halite, is an ionic compound with the chemical formula NaCl, representing a 1:1 ratio of sodium and chloride ions. Sodium chloride is the primary salt in seawater and in the extracellular fluid of many multicellular organisms. It is listed on the World Health Organization Model List of Essential Medicines.
- Type
- Small Molecule
- Groups
- Approved, Vet approved
- Structure
Structure for Sodium chloride (DB09153)
- Weight
- Average: 58.443
Monoisotopic: 57.958622382 - Chemical Formula
- ClNa
- Synonyms
- Cloruro sódico
- Natriumchlorid
- Natrum muriaticum
- Sodium chloride
- External IDs
- B1655
- LS-1700
- NSC-77364
Pharmacology
- Indication
This intravenous solution is indicated for use in adults and pediatric patients as a source of electrolytes and water for hydration. Also, designed for use as a diluent and delivery system for intermittent intravenous administration of compatible drug additives.
Reduce drug development failure ratesBuild, train, & validate machine-learning modelswith evidence-based and structured datasets.Build, train, & validate predictive machine-learning models with structured datasets.- Associated Conditions
- Allergic Rhinitis (AR)
- Corneal Edema
- Dehydration
- Dehydration Hypertonic
- Fluid Loss
- Hemodilution
- Hypokalemia
- Hyponatremia
- Hypotonic Dehydration
- Hypovolaemia
- Increase in Intracranial Pressure (ICP)
- Increased Intra Ocular Pressure (IOP)
- Inflammation of the Nasal Mucosa
- Isotonic Dehydration
- Metabolic Acidosis
- Nasal Congestion
- Nasal irritation
- Oliguria caused by Acute Renal Failure (ARF)
- Potassium deficiency
- Sinusitis
- Skin Irritation
- Sodium Depletion
- Dryness of the nose
- Hypochloremic state
- Mild Metabolic acidosis
- Mild, moderate Metabolic Acidosis
- Associated Therapies
- Electrolyte replacement
- Fluid replacement therapy
- Heart-Lung-Machine
- Oral rehydration therapy
- Parenteral Nutrition
- Parenteral rehydration therapy
- Peritoneal dialysis therapy
- Plasma Volume Replacement
- Regional Citrate Anticoagulation (RCA)
- Renal Replacement Therapies
- Urine alkalinization therapy
- Wound irrigation therapy
- Ear wax removal
- Fluid and electrolyte maintenance therapy
- Increased renal excretion of toxic substances
- Maintenance source of fluid and electrolytes
- Parenteral drug administration
- Reducing brain mass
- Contraindications & Blackbox Warnings
Avoid life-threatening adverse drug eventsImprove clinical decision support with information on contraindications & blackbox warnings, population restrictions, harmful risks, & more.Avoid life-threatening adverse drug events & improve clinical decision support.- Pharmacodynamics
Sodium, the major cation of the extracellular fluid, functions primarily in the control of water distribution, fluid balance, and osmotic pressure of body fluids. Sodium is also associated with chloride and bicarbonate in the regulation of the acid-base equilibrium of body fluid. Chloride, the major extracellular anion, closely follows the metabolism of sodium, and changes in the acid-base balance of the body are reflected by changes in the chloride concentration.
- Mechanism of action
Sodium and chloride — major electrolytes of the fluid compartment outside of cells (i.e., extracellular) — work together to control extracellular volume and blood pressure. Disturbances in sodium concentrations in the extracellular fluid are associated with disorders of water balance.
- Absorption
Absorption of sodium in the small intestine plays an important role in the absorption of chloride, amino acids, glucose, and water. Chloride, in the form of hydrochloric acid (HCl), is also an important component of gastric juice, which aids the digestion and absorption of many nutrients.
- Volume of distribution
The volume of distribution is 0.64 L/kg.
- Protein binding
Sodium is not bound by plasma proteins.
- Metabolism
The salt that is taken in to gastro intestinal tract remains for the most part unabsorbed as the liquid contents pass through the stomach and small bowel. On reaching the colon this salt, together with the water is taken in to the blood. As excesses are absorbed the kidney is constantly excreting sodium chloride, so that the chloride level in the blood and tissues remains fairly constant.Further more, if the chloride intake ceases, the kidney ceases to excrete chlorides. Body maintains an equilibrium retaining the 300gm of salt dissolved in the blood and fluid elements of the tissue dissociated into sodium ions and chloride ions.
- Route of elimination
Substantially excreted by the kidneys.
- Half-life
17 minutes
- Clearance
Not Available
- Adverse Effects
Improve decision support & research outcomesWith structured adverse effects data, including: blackbox warnings, adverse reactions, warning & precautions, & incidence rates.Improve decision support & research outcomes with our structured adverse effects data.- Toxicity
The rare inadvertent intravascular administration or rapid intravascular absorption of hypertonic sodium chloride can cause a shift of tissue fluids into the vascular bed, resulting in hypervolemia, electrolyte disturbances, circulatory failure, pulmonary embolism, or augmented hypertension.
- Pathways
- Not Available
- Pharmacogenomic Effects/ADRs
- Not Available
Interactions
- Drug Interactions
- This information should not be interpreted without the help of a healthcare provider. If you believe you are experiencing an interaction, contact a healthcare provider immediately. The absence of an interaction does not necessarily mean no interactions exist.
Drug Interaction Integrate drug-drug
interactions in your softwareLithium carbonate Sodium chloride may increase the excretion rate of Lithium carbonate which could result in a lower serum level and potentially a reduction in efficacy. Lithium citrate Sodium chloride may increase the excretion rate of Lithium citrate which could result in a lower serum level and potentially a reduction in efficacy. Lithium hydroxide Sodium chloride may increase the excretion rate of Lithium hydroxide which could result in a lower serum level and potentially a reduction in efficacy. Tolvaptan The risk or severity of adverse effects can be increased when Sodium chloride is combined with Tolvaptan. 
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- No interactions found.
Products
Drug product information from 10+ global regionsOur datasets provide approved product information including:dosage, form, labeller, route of administration, and marketing period.Access drug product information from over 10 global regions.- Active Moieties
Name Kind UNII CAS InChI Key Sodium cation ionic LYR4M0NH37 17341-25-2 FKNQFGJONOIPTF-UHFFFAOYSA-N Chloride ion ionic Q32ZN48698 16887-00-6 VEXZGXHMUGYJMC-UHFFFAOYSA-M - Brand Name Prescription Products
Name Dosage Strength Route Labeller Marketing Start Marketing End Region Image 0.45% Sodium Chloride Injection USP Solution 4.5 mg / mL Intravenous B. Braun Medical Inc. 1993-12-31 Not applicable Canada 
0.9% Sodium Chloride Injection, solution 900 mg/100mL Intravenous HF Acquisition Co LLC, DBA HealthFirst 2018-10-18 Not applicable US 
0.9% Sodium Chloride Injection, solution 900 mg/100mL Intravenous HF Acquisition Co LLC, DBA HealthFirst 2018-10-16 Not applicable US 0.9% Sodium Chloride Injection, solution 9 mg/1mL Intramuscular; Intravenous; Subcutaneous HF Acquisition Co LLC, DBA HealthFirst 2019-07-18 Not applicable US 0.9% Sodium Chloride Injection, solution 900 mg/100mL Intravenous HF Acquisition Co LLC, DBA HealthFirst 2020-04-07 Not applicable US 0.9% Sodium Chloride Injection, solution 900 mg/100mL Intravenous Sc Infomed Fluids Srl 2017-04-24 2017-04-24 US 0.9% Sodium Chloride Injection, solution 900 mg/100mL Intravenous HF Acquisition Co LLC, DBA HealthFirst 2020-05-21 Not applicable US 0.9% Sodium Chloride Injection, solution 900 mg/100mL Intravenous HF Acquisition Co LLC, DBA HealthFirst 2020-04-07 Not applicable US 0.9% Sodium Chloride Irrigant 900 mg/100mL Irrigation HF Acquisition Co LLC, DBA HealthFirst 2018-10-18 Not applicable US 0.9% Sodium Chloride Injection Solution 900 mg / 100 mL Intravenous Fresenius Kabi 2013-12-10 Not applicable Canada - Generic Prescription Products
Name Dosage Strength Route Labeller Marketing Start Marketing End Region Image 0.9% Sodium Chloride Injection, solution 9 g/1000mL Intravenous HF Acquisition Co LLC, DBA HealthFirst 2022-07-31 Not applicable US 0.9% Sodium Chloride Injection, solution 9 mg/1mL Intravenous HF Acquisition Co LLC, DBA HealthFirst 2021-07-17 Not applicable US 3% Sodium Chloride Injection, solution 3 g/100mL Intravenous Becton Dickinson and Company 2020-02-28 Not applicable US Amphenol-40 Injection, solution 9 mg/1mL Intramuscular; Intravenous; Subcutaneous It3 Medical Llc 2017-03-01 Not applicable US Bacteriostatic Sodium Chloride Injection 9 mg/1mL Intramuscular; Intravenous; Subcutaneous Fresenius Kabi USA, LLC 2000-08-08 Not applicable US Bacteriostatic Sodium Chloride Injection 9 mg/1mL Intramuscular; Intravenous; Subcutaneous Cardinal Health 2000-08-08 2016-03-31 US Corvatrol 0.9% Injection 9 mg/1mL Intramuscular; Intravenous; Subcutaneous It3 Medical Llc 2017-03-01 Not applicable US HAEMONETICS 0.9 % Sodium Chloride Solution 900 mg/100mL Extracorporeal Haemonetics Corporation 2013-01-07 Not applicable US Sodium chloride Injection, solution 450 mg/100mL Intravenous Fresenius Kabi USA, LLC 2018-07-23 Not applicable US Sodium Chloride Injection, solution 9 mg/1mL Intravenous Fresenius Kabi USA, LLC 2017-09-19 Not applicable US - Over the Counter Products
Name Dosage Strength Route Labeller Marketing Start Marketing End Region Image 0.9% SODIUM CHLORIDE (500ML ROUND PLASTIC CONTAINER) Solution 0.9 % POLYLAB BIOTECH SDN. BHD. 2016-03-03 2019-05-10 Malaysia 
0.9% SODIUM CHLORIDE PARENTERAL SOLUTION (1000ML PLASTIC) Solution 0.9 % Parenteral POLYLAB BIOTECH SDN. BHD. 2017-07-04 2019-05-10 Malaysia Altachlore Sodium Chloride Hypertonicity Solution / drops 50 mg/1mL Ophthalmic Altaire Pharmaceuticals Inc. 2002-09-24 Not applicable US Ancient Secrets Breathe Again Aerosol, spray 20 mg/100mL Nasal Lotus Brands, Inc. 2011-08-15 Not applicable US Ancient Secrets Breathe Again Childrens Aerosol, spray 20 mg/100mL Nasal Lotus Brands, Inc. 2011-08-15 2015-06-01 US Aqua Maris Baby Liquid 9 mg/1mL Nasal JGL d. d. 2022-12-20 Not applicable US Aqua Maris Baby Liquid 9 mg/1mL Nasal JGL d. d. 2022-05-04 Not applicable US Aqua Maris Baby Liquid 11.25 mg/1mL Nasal Jgl North America Llc 2010-07-08 Not applicable US Aqua Maris Classic Spray 10.5 mg/1mL Nasal JGL d. d. 2022-05-06 Not applicable US Aqua Maris Clean Spray 9 mg/1mL Nasal JGL d. d. 2022-05-05 Not applicable US - Mixture Products
Name Ingredients Dosage Route Labeller Marketing Start Marketing End Region Image (20 Mmol/l) Potassium Chloride In 3.3% Dextrose and 0.3% Sodium Chloride Injection USP Sodium chloride (300 mg / 100 mL) + Dextrose, unspecified form (3.3 g / 100 mL) + Potassium chloride (150 mg / 100 mL) Solution Intravenous Baxter Laboratories 1978-12-31 Not applicable Canada (20 Mmol/l) Potassium Chloride In 5% Dextrose and 0.9% Sodium Chloride Injection USP Sodium chloride (900 mg / 100 mL) + Dextrose, unspecified form (5 g / 100 mL) + Potassium chloride (150 mg / 100 mL) Solution Intravenous Baxter Laboratories 1990-12-31 Not applicable Canada (20mmol/l) Potassium Chloride In 0.9% Sodium Chloride Injection USP Sodium chloride (900 mg / 100 mL) + Potassium chloride (150 mg / 100 mL) Solution Intravenous Baxter Laboratories 1989-12-31 Not applicable Canada (20mmol/l) Potassium Chloride In 5% Dextrose and 0.2% Sodium Chloride Injection USP Sodium chloride (200 mg / 100 mL) + Dextrose, unspecified form (5 g / 100 mL) + Potassium chloride (150 mg / 100 mL) Solution Intravenous Baxter Laboratories 1989-12-31 2016-07-15 Canada (20mmol/l) Potassium Chloride In 5% Dextrose and 0.45% Sodium Chloride Injection USP Sodium chloride (450 mg / 100 mL) + Dextrose, unspecified form (5 g / 100 mL) + Potassium chloride (150 mg / 100 mL) Solution Intravenous Baxter Laboratories 1989-12-31 Not applicable Canada (40 Mmol/l) Potassium Chloride In 0.9% Sodium Chloride Injection USP Sodium chloride (900 mg / 100 mL) + Potassium chloride (300 mg / 100 mL) Liquid Intravenous Baxter Laboratories 1989-12-31 Not applicable Canada (40 Mmols/l) Potassium Chloride In Lactated Ringer's Injection USP Sodium chloride (600 mg / 100 mL) + Calcium chloride (20 mg / 100 mL) + Sodium lactate (310 mg / 100 mL) + Potassium chloride (328 mg / 100 mL) Solution Intravenous Baxter Laboratories 2002-12-11 2016-07-15 Canada (40mmol/l) Potassium Chloride In 3.3% Dextrose and 0.3% Sodium Chloride Injection USP Sodium chloride (300 mg / 100 mL) + Dextrose, unspecified form (3.3 g / 100 mL) + Potassium chloride (300 mg / 100 mL) Solution Intravenous Baxter Laboratories 1978-12-31 Not applicable Canada (40mmol/l)potassium Chloride In 5% Dextrose and 0.45% Sodium Chloride Injection USP Sodium chloride (450 mg / 100 mL) + Dextrose, unspecified form (5 g / 100 mL) + Potassium chloride (300 mg / 100 mL) Solution Intravenous Baxter Laboratories 1989-12-31 Not applicable Canada %5 DEKSTROZ %0,2 SODYUM KLORUR COZELTISI SETLI, 100 ML Sodium chloride (5 %) + D-glucose monohydrate (0.2 %) Solution Intravenous KOÇAK FARMA İLAÇ VE KİMYA SAN. A.Ş. 2020-08-14 Not applicable Turkey 
- Unapproved/Other Products
Name Ingredients Dosage Route Labeller Marketing Start Marketing End Region Image %0,9 IZOTONIK 1000 ML SOLUSYON(SETLI) Sodium chloride (0.9 %) Solution Intravenous POLİFARMA İLAÇ SAN. VE TİC. A.Ş. 2020-08-14 Not applicable Turkey %0,9 IZOTONIK 500 ML SOLUSYON(SETLI) Sodium chloride (0.9 %) Solution Intravenous POLİFARMA İLAÇ SAN. VE TİC. A.Ş. 2020-08-14 Not applicable Turkey %0,9 IZOTONIK 500 ML SOLUSYON(SETSIZ) Sodium chloride (0.9 %) Solution Intravenous POLİFARMA İLAÇ SAN. VE TİC. A.Ş. 2020-08-14 Not applicable Turkey %0,9 IZOTONIK SODYUM KLORUR 250 ML SOLUSYON(SETLI) Sodium chloride (0.9 %) Solution Intravenous POLİFARMA İLAÇ SAN. VE TİC. A.Ş. 2020-08-14 Not applicable Turkey %0,9 IZOTONIK SODYUM KLORUR 250 ML SOLUSYON(SETSIZ) Sodium chloride (0.9 %) Solution Intravenous POLİFARMA İLAÇ SAN. VE TİC. A.Ş. 2020-08-14 Not applicable Turkey %09 IZOTONIK 1000 ML SOLUSYON Sodium chloride (9 %) Solution Intravenous POLİFARMA İLAÇ SAN. VE TİC. A.Ş. 2020-08-14 Not applicable Turkey %3 SODYUM KLORUR SOLUSYON 1000 ML CAM(SETLI) Sodium chloride (3 %) Solution Intravenous POLİFARMA İLAÇ SAN. VE TİC. A.Ş. 2020-08-14 Not applicable Turkey %3 SODYUM KLORUR SOLUSYON 1000 ML CAM(SETSIZ) Sodium chloride (3 %) Solution Intravenous POLİFARMA İLAÇ SAN. VE TİC. A.Ş. 2020-08-14 Not applicable Turkey %3 SODYUM KLORUR SOLUSYON 500 ML CAM(SETLI) Sodium chloride (3 %) Solution Intravenous POLİFARMA İLAÇ SAN. VE TİC. A.Ş. 2020-08-14 Not applicable Turkey %3 SODYUM KLORUR SOLUSYON 500 ML CAM(SETSIZ) Sodium chloride (3 %) Solution Intravenous POLİFARMA İLAÇ SAN. VE TİC. A.Ş. 2020-08-14 Not applicable Turkey
Categories
- ATC Codes
- B05XA03 — Sodium chloride
- B05XA — Electrolyte solutions
- B05X — I.V. SOLUTION ADDITIVES
- B05 — BLOOD SUBSTITUTES AND PERFUSION SOLUTIONS
- B — BLOOD AND BLOOD FORMING ORGANS
- B05CB — Salt solutions
- B05C — IRRIGATING SOLUTIONS
- B05 — BLOOD SUBSTITUTES AND PERFUSION SOLUTIONS
- B — BLOOD AND BLOOD FORMING ORGANS
- Drug Categories
- Alimentary Tract and Metabolism
- Blood and Blood Forming Organs
- Blood Substitutes and Perfusion Solutions
- Chlorides
- Chlorine Compounds
- Diluents
- EENT Drugs, Miscellaneous
- Electrolyte Solutions
- I.V. Solution Additives
- Irrigating Solutions
- Mineral Supplements
- Other Miscellaneous Therapeutic Agents
- Replacement Preparations
- Respiratory Agents, Miscellaneous
- Salt Solutions
- Sodium
- Sodium Compounds
- Chemical TaxonomyProvided by Classyfire
- Description
- This compound belongs to the class of inorganic compounds known as alkali metal chlorides. These are inorganic compounds in which the largest halogen atom is Chlorine, and the heaviest metal atom is an alkali metal.
- Kingdom
- Inorganic compounds
- Super Class
- Mixed metal/non-metal compounds
- Class
- Alkali metal salts
- Sub Class
- Alkali metal chlorides
- Direct Parent
- Alkali metal chlorides
- Alternative Parents
- Inorganic sodium salts / Inorganic chloride salts
- Substituents
- Alkali metal chloride / Inorganic chloride salt / Inorganic salt / Inorganic sodium salt
- Molecular Framework
- Not Available
- External Descriptors
- inorganic chloride, inorganic sodium salt (CHEBI:26710)
- Affected organisms
- Not Available
Chemical Identifiers
- UNII
- 451W47IQ8X
- CAS number
- 7647-14-5
- InChI Key
- FAPWRFPIFSIZLT-UHFFFAOYSA-M
- InChI
- InChI=1S/ClH.Na/h1H;/q;+1/p-1
- IUPAC Name
- sodium chloride
- SMILES
- [Na+].[Cl-]
References
- General References
- External Links
- MSDS
- Download (89.8 KB)
Clinical Trials
- Clinical Trials
Phase Status Purpose Conditions Count 4 Active Not Recruiting Other Ehlers-Danlos Syndrome (EDS) / Local Anaesthesia therapy 1 4 Active Not Recruiting Prevention Ketamine / Postpartum Depression / Prenatal Depression 1 4 Active Not Recruiting Treatment Allergic Rhinitis (AR) / Allergy to Tree Pollen / Seasonal Allergic Rhinitis 1 4 Active Not Recruiting Treatment Burns / Surgery / Tranexamic Acid / Wounds and Injuries 1 4 Active Not Recruiting Treatment Children, Only / Pain / Remifentanil / Tonsillectomy 1 4 Active Not Recruiting Treatment Chronic (Inactive) Thyroid Eye Disease / Thyroid Eye Disease 1 4 Active Not Recruiting Treatment Endothelial Dysfunction / Iron Toxicity / Renal Anemia / Stress Oxidative 1 4 Active Not Recruiting Treatment Nerve Block / Postoperative pain 1 4 Active Not Recruiting Treatment Stroke, Acute 1 4 Completed Not Available Brain Swelling 1
Pharmacoeconomics
- Manufacturers
- Not Available
- Packagers
- Not Available
- Dosage Forms
Form Route Strength Solution Intravenous 0.9 % Solution Intravenous 20 % Solution Intravenous 9 % Solution Intravenous 3 % Solution Intravenous 4.5 mg / mL Solution Intramuscular; Intravenous; Subcutaneous 9 mg / mL Solution Intravenous 900 mg / 100 mL Solution Irrigation 0.9 % Solution Irrigation 900 mg / 100 mL Solution Irrigation 1.6 g / 100 mL Injection Intravenous 50 g/L Solution Irrigation 12 g / 100 mL Solution Intravenous 20 % w/v Solution Intravenous 23.4 % Liquid Intravenous 30 mg / mL Kit Irrigation; Ophthalmic; Respiratory (inhalation); Topical Cream; irrigant; kit; liquid; ointment; swab Irrigation; Ophthalmic; Topical Irrigant; kit; liquid; swab Irrigation; Ophthalmic; Topical Kit Irrigation; Oral; Respiratory (inhalation); Topical Kit Irrigation; Ophthalmic; Oral; Respiratory (inhalation); Topical Solution Intravenous 5 g / 100 mL Solution Hemodialysis 0.257 g/1000ml Kit; solution Intravenous Solution Respiratory (inhalation) 0.45 % Solution Respiratory (inhalation) 0.9 % Solution Respiratory (inhalation) 450 mg / 100 mL Solution Respiratory (inhalation) 900 mg / 100 mL Solution Parenteral 9 mg Kit Intradermal; Subcutaneous Solution Topical 9 mg/ml Solution; spray Nasal 9 mg/ml Solution Irrigation; Parenteral Powder, for solution Intraocular Solution Intraocular Aerosol, spray Nasal 20 mg/100mL Liquid Topical Liquid Nasal 11.25 mg/1mL Liquid Nasal 9 mg/1mL Spray Nasal 10.5 mg/1mL Spray Nasal 9 mg/1mL Spray Auricular (otic) 11.25 mg/1mL Spray Nasal 21 mg/1mL Spray Nasal 36 mg/1mL Spray Oral 37.5 mg/1mL Spray Nasal 0.9 mg/100mL Spray Nasal 0.9 g/100mL Inhalant Respiratory (inhalation) 1.7 mg/1mL Solution Intravenous drip Liquid Respiratory (inhalation) 0.9 % Solution Ophthalmic Ointment Topical 30 mg/1g Liquid Dental 0.5 g/100mL Solution / drops Nasal Solution; spray Nasal Kit; powder, for solution; tablet, delayed release Oral Kit; powder, for solution Hemodialysis Powder, for solution Oral 1.685 g Liquid; powder, for solution Subcutaneous Solution Hemodialysis; Intravenous Solution Hemodialysis; Intravenous 0.187 g/L Liquid Oral 0.5 g/100mL Solution / drops; suspension / drops Spray Nasal Aerosol, metered Respiratory (inhalation) .9 % Concentrate; kit; solution Ophthalmic Kit; solution Intraocular Liquid Topical 0.495 g/50mL Liquid Topical 0.99 g/100mL Liquid Topical 2.97 g/300mL Liquid Topical 4.95 g/500mL Powder Topical 60 g/300g Solution Intraperitoneal 0.2573 g/l Solution Intraperitoneal 0.1838 g/L Solution Solution Intra-arterial Enema Rectal 15 % Solution Nasal .9 % Solution Nasal; Ophthalmic 900 mg/100mL Swab Topical 0.9 g/100mL Liquid Nasal 6.5 mg/1mL Solution Intramuscular; Intravenous; Subcutaneous 9 mg Solution Intravenous 9 g Solution Intravenous; Irrigation 9 mg Solution, concentrate Intravenous 11.7 g Solution Intravenous 1.17 g Solution Intravenous 20 mEq Solution Parenteral 20 MBq Solution Intravenous 0.009 g Solution Intravenous 900 mg Injection Intravenous 10 g Solution Intravenous 1.1688 g Solution Intravenous 116.9 mg Powder, for solution Nasogastric Solution Intravenous 0.27 g/1000ml Injection, powder, lyophilized, for solution Hemodialysis Liquid Ophthalmic 0.9 g/100mL Liquid Epidural; Infiltration; Subcutaneous Ointment Topical 5 % Solution Topical 5 % Solution Ophthalmic 5 % Kit; powder Nasal Powder Nasal Spray Nasal 0.9 g/100g Solution Irrigation Paste, dentifrice Oral Solution Intraperitoneal Injection Intravenous 5.0 % w/v Liquid Intravenous Injection Intravenous 5 g/100ml Injection Intravenous Solution Respiratory (inhalation) .45 % Solution Respiratory (inhalation) 10 % Solution Respiratory (inhalation) 3 % Liquid Topical .9 % Solution Intraperitoneal; Irrigation Solution Intraperitoneal 18.3 mg Injection, solution Intraperitoneal Injection Subcutaneous 4.5 mg/0.5mL Liquid Intradermal; Percutaneous; Subcutaneous Liquid Subcutaneous Solution Intravenous 1.47 mg/1ml Kit Epidural; Infiltration; Intracaudal; Subcutaneous; Topical Injection, solution, concentrate Intramuscular Spray Topical Spray Nasal 0.39 mL/60mL Solution / drops Nasal 180 mg/20ml Solution Intravenous 4.21 g/1000ml Kit Intra-articular; Intralesional; Intramuscular; Soft tissue; Topical Liquid Ophthalmic 0.48 % Granule, for solution Oral Injection, solution Intravenous 1000 ML Solution Intrathecal Injection Intrathecal Solution Intravenous; Subcutaneous Powder Oral Solution Rectal 2.5 g Enema; kit; tablet Rectal Spray Nasal 30 mg/1mL Kit Epidural; Infiltration Solution Intraperitoneal 25.7 mg/100ml Solution Nasal 0.29 mg/44mL Kit; liquid; powder, for solution Intramuscular; Subcutaneous Liquid; powder, for solution Intramuscular; Subcutaneous Solution Irrigation; Topical 0.9 g Liquid Topical 1.5 g/100mL Granule, for solution Oral 64 g Solution Intra-articular; Irrigation 0.009 g Solution Parenteral 0.9 g Solution Intrasinal; Nasal 0.9 mg Solution, concentrate Hemodialysis Spray Oral Aerosol, spray Oral Injection Parenteral Injection, solution Parenteral Powder, for solution Nasogastric; Oral Solution Extracorporeal 9 g Solution Hemodialysis Solution Hemodialysis 7.77 g/l Solution Hemodialysis 8.46 g/l Solution Extracorporeal 900 mg/100mL Solution Extracorporeal Solution Hemodialysis 8.8 g/l Solution Hemodialysis 66 g/l Solution Hemodialysis 8.85 g/l Liquid Hemodialysis Solution Hemodialysis 6.77 g/l Injection Intravenous 10 iu/ml Solution Oral 0.2892 g Solution Ophthalmic 50 mg Solution Conjunctival; Ophthalmic Solution Nasal Enema Rectal 6 g/20ml Liquid; powder, for solution Intramuscular Solution Respiratory (inhalation) Spray Nasal Liquid Nasal .65 g/100mL Solution Intravenous 0.9 % w/v Injection, solution Intravenous 20 % Injection Intravenous Liquid Intraperitoneal Solution Hemodialysis; Intraperitoneal Liquid Intravesical Liquid Intraocular Solution Intravenous Solution Solution Intravenous Kit Intravenous; Topical Irrigant Irrigation 0.9 % Solution Intravenous 1000 ml Solution Intravenous 500 ml Solution 3000 ml Solution 1000 ml Solution 500 ml Liquid Infiltration; Subcutaneous; Topical Solution Rectal 150 mg/ml Tablet Vaginal Injection Intravenous 20 mg/100ml Solution, for slush Irrigation Gel Vaginal Injection Intravenous 0.027 % w/v Solution Intravenous 0.45 % Solution Intravenous 30 mg/mL Solution Intravenous 100 ml Solution Intravenous 150 ml Solution Intravenous 250 ml Solution Intravenous 50 ml Solution / drops Ophthalmic 0.9 % Solution Conjunctival; Ophthalmic 0.09 g Injection, solution Injection, solution; kit Intravenous 9 g/1000mL Injection, solution; kit; solution Intravenous; Topical Liquid Oral Powder, for solution Oral 289.99 mg Powder, for solution Subcutaneous Injection Subcutaneous Liquid Buccal Spray Buccal Powder, for solution Oral 13.125 g Powder, for solution Oral 13.125 G Injection, solution, concentrate Oral Kit Oral Kit; solution Oral Injection, solution Hemodialysis; Intravenous Solution Ophthalmic 20 mg/1mL Solution Ophthalmic 50 mg/1mL Liquid Intraocular; Ophthalmic 2 % Solution Intravenous 117 mg Lotion Topical .65 mL/100mL Solution Nasal; Respiratory (inhalation) 9 mg Spray Nasal 9.5 mg/1mL Spray Nasal 2600 mg/100mL Solution Intrasinal; Nasal 900 mg Solution Nasal; Respiratory (inhalation) 6.5 mg Solution Nasal; Respiratory (inhalation) 9.054 mg Solution Intrasinal; Nasal 6.5 mg Spray Nasal 3 mL/100mL Spray Nasal 1.2 mg/10mL Solution Intravenous 9 g/L Solution Intravenous 1.169 g Injection, solution Parenteral 9 mg/ml Kit; solution Intraocular; Irrigation Solution Intrasinal; Nasal 0.65 g Solution Topical 9 mg Tablet Oral 1 g/1 Emulsion Parenteral Emulsion Intravenous Injection, emulsion Intravenous 4.656 g/1000ml Injection, emulsion Intravenous 6.792 g/1000ml Injection, solution, concentrate Intravenous Solution Intraperitoneal 0.184 g/l Injection, emulsion Intravenous Ointment Ophthalmic 50 mg/g Solution, concentrate Oral Solution Intraocular; Ophthalmic Solution Intraocular; Irrigation Liquid; mouthwash Oral Solution Extracorporeal; Intrabiliary; Intracardiac Solution Auricular (otic) Injection, solution; kit; solution Epidural; Infiltration; Intracaudal; Intravenous; Perineural; Topical Injection, solution; injection, suspension; kit; solution Epidural; Infiltration; Intra-articular; Intracaudal; Intralesional; Intramuscular; Intravenous; Perineural; Soft tissue; Topical Injection, solution; injection, suspension; kit; solution Epidural; Infiltration; Intra-articular; Intracaudal; Intramuscular; Intravenous; Perineural; Topical Injection; injection, solution; kit; solution Epidural; Intracaudal; Intravenous; Perineural; Topical Injection, solution; kit; solution Epidural; Intracaudal; Intravenous; Perineural; Topical Solution Oral Powder Oral 238.33 g Liquid Intradermal; Subcutaneous Injection, solution Solution Conjunctival; Ophthalmic 90000 mg Solution 0.9 % Irrigant Irrigation Injection, solution Intravenous Injection Intravenous 30 mg/100ml Injection, solution Intra-arterial Kit; powder, for solution Oral Powder, for solution Oral Solution Intravenous 3.00 g/1000ml Solution Hemodialysis; Intravenous 0.27 g/l Kit Hemodialysis Solution Hemodialysis 0.257 g/l Enema Rectal Enema Rectal 25 % w/v Injection Intravenous 0.21 g/100ml Douche Vaginal Powder, for solution Intravenous Patch Transdermal 0.03 g/1g Kit; liquid; powder Intralesional; Subcutaneous Injection, solution Extracorporeal Solution Intravenous 5.03 g/l Liquid; powder, for solution Intravenous; Subcutaneous Solution Intravenous 0.1 g/500ml Solution Irrigation; Topical Injection, solution Irrigation Solution Ophthalmic 0.9 % w/v Solution Unknown Powder, for solution Intramuscular; Subcutaneous Solution Ophthalmic 50.00 mg/ml Spray Nasal 6.5 mg/1mL Spray Oral 6.5 mg/1mL Spray Nasal 2.65 mg/100mL Liquid Nasal .9 % Gel Nasal 0.9 g/100mL Cloth Topical 0.9 g/100mL Gel Nasal Aerosol Oral Injection Intravenous 0.9 % w/v Paste, dentifrice Dental Liquid Topical 5 g/100mL Liquid Topical 0.7 % Powder Topical Solution Nasal 20 ml Injection Intravenous 0.09 % Injection, solution Intravenous 0.9 % Injection Intravenous 0.9 % Liquid Epidural Powder, for solution Nasal Kit; powder, for solution Nasal Gel Nasal 0.9 mg/100mL Kit; powder; solution Nasal Injection, solution Intravenous Injection, solution Parenteral Solution Irrigation Solution Intravenous 2.25 g Solution Irrigation; Parenteral 0.9 g Solution Irrigation 0.9 g Solution Intravenous 0.1169 g Solution Intravenous 0.9 g Injection, solution Intravenous 3 % Injection, solution Intravenous 5 % Injection, solution Parenteral 0.9 % Injection, solution, concentrate Intravenous 2 MEQ/ML Solution Parenteral 0.9 % Solution Parenteral 9 % Injection, solution Parenteral 20 MEQ Injection, solution Parenteral 20 MEQ/10ML Injection, solution Intravenous 18 MG/2ML Injection, solution Intravenous 180 MG/20ML Injection, solution Intravenous 45 MG/5ML Injection, solution Intravenous 90 MG/10ML Injection, solution Irrigation 0.9 % Solution, concentrate Parenteral 0.117 g/ml Injection, solution, concentrate Intravenous Injection, solution Parenteral 5 % Injection, solution, concentrate Intravenous 0.175 g Injection, solution, concentrate Intravenous 1.17 g Injection, solution, concentrate Intravenous 1.75 g Solution Irrigation; Parenteral 0.9 % Injection, solution Intravenous 0.45 % Injection, solution Parenteral 0.45 % Injection, solution Parenteral 3 % Injection, solution, concentrate Intravenous 3 % Injection, solution, concentrate Intravenous 3 mEq/ml Injection, solution, concentrate Intravenous 5 % Solution Intravenous 5 % Solution, concentrate Intravenous 0.117 g/ml Solution, concentrate Intravenous 0.175 g/ml Solution Parenteral Solution, concentrate Parenteral 0.175 g/ml Solution Intravenous 3 g Powder Hemodialysis Inhalant Respiratory (inhalation) 0.9 mg/100mL Injection Injection Intramuscular; Intravenous; Subcutaneous 0.9 mg/10mL Injection Intramuscular; Intravenous; Subcutaneous 234 mg/1mL Injection Intramuscular; Intravenous; Subcutaneous 9 mg/1mL Injection Intravascular .9 mg/1mL Injection Intravenous 0.45 g/50mL Injection Intravenous 0.9 g/100mL Injection Intravenous 450 mg/50mL Injection Intravenous 450 mg/100mL Injection Intravenous 9 mg/1mL Injection Intravenous 900 mg/100mL Injection Intravenous 900 mg/1000mL Injection, solution Intramuscular; Intravenous; Subcutaneous 9 mg/1mL Injection, solution Intravenous 0.45 g/100mL Injection, solution Intravenous 0.9 g/100mL Injection, solution Intravenous 1125 mg/250mL Injection, solution Intravenous 146 mg/1mL Injection, solution Intravenous 225 mg/50mL Injection, solution Intravenous 2250 mg/500mL Injection, solution Intravenous 234 mg/1mL Injection, solution Intravenous 3 g/100mL Injection, solution Intravenous 4.5 g/1000mL Injection, solution Intravenous 450 mg/100mL Injection, solution Intravenous 450 mg/50mL Injection, solution Intravenous 5 g/100mL Injection, solution Intravenous 9 mg/1mL Injection, solution Intravenous 9 g/1 Injection, solution Intravenous 9 g/1000mL Injection, solution Intravenous 900 mg/100mL Injection, solution, concentrate Intravenous 2.5 meq/1mL Injection, solution, concentrate Intravenous 2.92 g/20mL Injection, solution, concentrate Intravenous 234 mg/1mL Injection, solution, concentrate Intravenous 4 meq/1mL Injection, solution, concentrate Intravenous 5.84 g/40mL Irrigant Irrigation 0.9 g/100mL Irrigant Irrigation 450 mg/100mL Irrigant Irrigation 9 g/1000mL Irrigant Irrigation 900 mg/100mL Ointment Ophthalmic 50 mg/1g Solution Intravenous 0.45 g/100mL Solution Intravenous 0.9 g/100mL Solution Respiratory (inhalation) 0.027 mg/3mL Solution / drops Ophthalmic 50 mg/1mL Solution, concentrate Oral 936 mg/4mL Injection Intravenous 5.5 g/100ml Injection Intravenous 2.75 g/100ml Liquid Intravenous 450 mg / 100 mL Solution Ophthalmic 0.9 g/100mL Liquid Intravenous; Subcutaneous 9 mg / mL Solution Intravenous 3 g / 100 mL Liquid Intravenous 23.4 g / 100 mL Liquid Intramuscular; Intravenous; Subcutaneous 9 mg / mL Injection Intravenous 20 g/100ml Solution Irrigation 0.9 g/100mL Inhalant Respiratory (inhalation) 9 g/1L Liquid Intravenous 9 mg / mL Liquid Intramuscular; Intravenous; Subcutaneous .9 % Liquid Intravenous 234 mg / mL Solution Intravenous 234 mg / mL Liquid Intravenous .9 % Solution Intravenous 9 mg / mL Solution Intravenous 50 mg / mL Injection Intravenous; Subcutaneous 0.9 g/100ml Injection Intravenous; Subcutaneous 0.9 % w/v Liquid Parenteral 9 mg / mL Solution Intramuscular; Intraperitoneal; Intravenous; Subcutaneous 0.9 % Solution Intramuscular; Intraperitoneal; Intravenous; Subcutaneous 9 mg / mL Solution Intramuscular; Intravenous; Subcutaneous 234 mg / mL Solution Intravenous 146 mg / mL Injection Intravenous 0.45 % Solution Intramuscular; Intravenous; Subcutaneous 0.45 % Solution Intramuscular; Intravenous; Subcutaneous 0.9 % Solution Intravenous; Subcutaneous 9 mg / mL Injection Intravenous 0.45 g/100ml Solution Intravenous 9 g/1000ml Injection Intravenous 3 g/100ml Liquid Irrigation; Topical 9 mg / mL Solution Intraperitoneal; Irrigation 9 mg / mL Solution Intraperitoneal; Irrigation; Topical 9 mg / mL Tablet Oral 500 mg/1 Tablet Irrigation 1 g / tab Tablet Oral 600 mg Injection, solution, concentrate Intravenous; Subcutaneous 234 mg/1mL Solution Parenteral 2 g Powder, for solution Oral 2.9 g Solution Parenteral 0.117 g Solution Intravenous 9 mg Solution Intravenous 0.225 g Solution Respiratory (inhalation) Kit Intravenous Liquid Topical 70 mg/1mL Solution Parenteral Liquid; powder, for solution Intravenous Solution Intrasinal; Nasal 0.9 g Solution Intrasinal; Oral 0.9 g Solution Nasal; Respiratory (inhalation) 0.009 g Solution Nasal; Respiratory (inhalation) 0.9 g Suspension Nasal; Respiratory (inhalation) 0.9 g Solution Respiratory (inhalation) 9 mg Solution Intrasinal; Nasal 9 mg Powder, for solution Hemodialysis Powder, for solution Oral 50 g Solution Intravenous 0.3675 g/1000ml Tablet Oral Paste, dentifrice Topical 0.7 g/100mL Liquid Irrigation Solution Conjunctival; Ophthalmic 50 mg Solution Intravenous; Irrigation Solution Intraocular; Intravenous Injection Intravenous 60 g/l Spray Nasal 3 g/100g Kit Nasal Enema Rectal Liquid Topical 6.5 mg/1mL Spray Nasal .65 g/100mL Kit Intramuscular; Intravenous Granule, for solution Nasal Solution; spray Nasal Liquid Ophthalmic Lotion Ophthalmic 0.9 g/100mL Enema Tablet 300 mg Tablet 600 mg - Prices
- Not Available
- Patents
Patent Number Pediatric Extension Approved Expires (estimated) Region US5945449 No 1999-08-31 2017-10-31 US US7300674 No 2007-11-27 2023-03-04 US US6077836 No 2000-06-20 2017-06-20 US US6248726 No 2001-06-19 2018-06-19 US US7291324 No 2007-11-06 2022-10-22 US US7169381 No 2007-01-30 2024-09-01 US US7658914 No 2010-02-09 2024-09-01 US US7084130 No 2006-08-01 2021-11-29 US US9326969 No 2016-05-03 2033-09-10 US US9592252 No 2017-03-14 2032-08-11 US US9707297 No 2017-07-18 2033-09-10 US US8999313 No 2015-04-07 2033-09-10 US US10016504 No 2018-07-10 2033-09-10 US US10646512 No 2020-05-12 2032-03-25 US US10792306 No 2020-10-06 2032-03-09 US US10780112 No 2020-09-22 2032-03-09 US US10918723 No 2021-02-16 2033-09-10 US US11529368 No 2012-03-09 2032-03-09 US
Properties
- State
- Solid
- Experimental Properties
- Not Available
- Predicted Properties
Property Value Source Water Solubility 108.0 mg/mL ALOGPS logP 0.06 ALOGPS logP -0.77 Chemaxon logS 0.26 ALOGPS pKa (Strongest Acidic) 3.09 Chemaxon Physiological Charge 1 Chemaxon Hydrogen Acceptor Count 0 Chemaxon Hydrogen Donor Count 0 Chemaxon Polar Surface Area 0 Å2 Chemaxon Rotatable Bond Count 0 Chemaxon Refractivity 0 m3·mol-1 Chemaxon Polarizability 1.78 Å3 Chemaxon Number of Rings 0 Chemaxon Bioavailability 1 Chemaxon Rule of Five Yes Chemaxon Ghose Filter No Chemaxon Veber's Rule Yes Chemaxon MDDR-like Rule No Chemaxon - Predicted ADMET Features
- Not Available
Spectra
- Mass Spec (NIST)
- Not Available
- Spectra
- Not Available
Drug created at October 01, 2015 19:54 / Updated at March 19, 2023 23:50