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Displaying results 2541 - 2550 of 10000 in total
  1. Drug

    Denifanstat

    go.drugbank.com/drugs/DB17576
    Investigational

    Denifanstat is an orally bioavailable fatty acid synthase (FASN) inhibitor. Due to its antineoplastic activities, it is being investigated for various cancers.

    Synonyms: Benzonitrile, 4-(1-(4-cyclobutyl-2-methyl-5-(3-methyl-1h-1,2,4-triazol-5-yl)benzoyl)-4-piperidinyl)-Categories: Heterocyclic Compounds, 1-Ring
  2. Drug

    ABBV-514

    go.drugbank.com/drugs/DB17586
    Investigational

    ABBV-514 is in development for the treatment of non-small cell lung cancer (NSCLC) and head and neck squamous cell carcinoma (HNSCC) as a single agent and in combination with a PD-1 inhibitor.[L45464]

  3. Drug

    Rocapuldencel-T

    go.drugbank.com/drugs/DB17588
    Investigational

    Rocapuldencel-T is an autologous dendritic cell immunotherapy that was investigated in NCT02662634 (A Safety and Feasibility Study of AGS-003-LNG for the Treatment of Stage 3 Non Small Cell Lung Cancer

    Synonyms: Rocapuldencel-T
  4. Drug

    NTLA-2002

    go.drugbank.com/drugs/DB17597
    Investigational

    NTLA-2002 is a lipid nanoparticle encapsulating single guide RNA (G012267) targeting the human KLKB1 gene and messenger RNA (mRNA000042) encoding Cas9. … It is an investigational therapy designed to knock out the target gene kallikrein B1 (KLKB1) to reduce plasma kallikrein activity, thereby preventing hereditary angioedema attacks.[L45738]

  5. Drug

    Emprumapimod

    go.drugbank.com/drugs/DB17603
    Investigational

    Emprumapimod is a potent, orally active and selective inhibitor of p38α mitogen-activated kinase inhibitor. It was investigated for dilated cardiomyopathy.

  6. Drug

    GC5107

    go.drugbank.com/drugs/DB17604
    Investigational

    GC5107 is an investigational intravenous immunoglobulin. It is marketed as IVIG-SN.

  7. Drug

    Intermedine

    go.drugbank.com/drugs/DB17612
    Investigational

    Synonyms: Valinamide, acetyl-l-seryl-l-tyrosyl-l-seryl-l-methionyl-l-glutamyl-l-histidyl-l-phenylalanyl-l-arginyl-l-tryptophyl-glycyl-l-lysyl-l-prolyl-, l-, N-acetyl-acth(1-13)-amideCategories: Heterocyclic Compounds, 2-Ring
  8. Drug

    PXL-770 free acid anhydrous

    go.drugbank.com/drugs/DB17615
    Experimental

    Synonyms: 2-chloro-3-(1-hydroxy-5,6,7,8-tetrahydronaphthalen-2-yl)-6-oxo- 5-phenyl-6,7-dihydrothieno(2, 3-b)pyridin-4-olateCategories: Heterocyclic Compounds, 1-Ring
  9. Drug

    Mubodina

    go.drugbank.com/drugs/DB17616
    Experimental

    Mubodina is an investigational drug developed by Adienne Pharma & Biotech. It is a recombinant human minibody directed against complement component C5.

    Synonyms: Neutralizing scFv dimer to C5 fused at the C terminal end to the Fc domains of human IgG1
  10. Drug

    Sinbaglustat

    go.drugbank.com/drugs/DB17619
    Experimental

    Synonyms: (2s,3r,4r,5s)-2-(hydroxymethyl)-1-pentyl-3,4,5-piperidinetriol, (2S,3R,4R,5S)-2-(Hydroxymethyl)-1-Pentylpiperidine-3,4,5-TriolCategories: Heterocyclic Compounds, 1-Ring