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MTL-CEBPA
go.drugbank.com/drugs/DB18143InvestigationalMTL-CEBPA is a SMARTICLES liposomal formulation of MTL-501, a small activating RNA (saRNA) oligonucleotide.
ESK981
go.drugbank.com/drugs/DB18155InvestigationalSynonyms: 4h-indazolo(5,4-a)pyrrolo(3,4-c)carbazol-4-one, 2,5,6,11,12,13-hexahydro-2-methyl-11-(2-methylpropyl)-8-(2-pyrimidinylamino)-, 4-methylbenzenesulfonate (1:1)Categories: Heterocyclic Compounds, 1-Ring, Heterocyclic Compounds, 2-RingBRG01
go.drugbank.com/drugs/DB18173InvestigationalBRG01 is a genetically modified autologous CAR-T cell therapy under investigation for the treatment of nasopharyngeal carcinoma.[L48111]
Etavopivat
go.drugbank.com/drugs/DB18176InvestigationalEtavopivat is a small molecule activator of erythrocyte pyruvate kinase (PKR) under investigation for the treatment of sickle cell disease.
Synonyms: 1-propanone, 1-(5-((2,3-dihydro-1,4-dioxino(2,3-b)pyridin-7-yl)sulfonyl)-3,4,5,6-tetrahydropyrrolo(3,4-c)pyrrol-2(1h)-yl)-3-hydroxy-2-phenyl-, (2s)-BNT111
go.drugbank.com/drugs/DB18177InvestigationalBNT111 is an investigational cancer immunotherapy under development for advanced melanoma. It consists of a fixed combination of mRNA-encoded, tumor-associated antigens.
LYT-200
go.drugbank.com/drugs/DB18179InvestigationalLYT-200 is a fully human IgG4 monoclonal antibody directed against galectin-9.
ATI-1013
go.drugbank.com/drugs/DB18185InvestigationalATI-1013 is a fully human nicotine-specific monoclonal antibody.
BMN-351
go.drugbank.com/drugs/DB18186InvestigationalBMN-351 is a fully modified 18-mer oligonucleotide with a TEG modification at its 5' end that binds to exon 51 of dystrophin pre-mRNA. … It is under investigation for the treatment of Duchenne Muscular Dystrophy (DMD).
EDI-200
go.drugbank.com/drugs/DB18188InvestigationalEDI-200 is a fusion protein consisting of human immunoglobim G1 constant region Fc region fused to the human receptor binding domain of ectodysplasin-A1.
AGuIX
go.drugbank.com/drugs/DB18189InvestigationalIt is under development as a radiosensitizer to be used during radiation treatment of malignant glioma. … AGuIX is an investigational brand product consisting of a polysiloxane matrix and gadolinium chelates.