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Drugs 6,189
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Displaying results 251 - 260 of 6189 in total

Drug
Ropivacaine
go.drugbank.com/drugs/DB00296
ApprovedInvestigational
Ropivacaine is an aminoamide local anesthetic drug marketed by AstraZeneca under the trade name Naropin. It exists as a racemate of its S- and R-enantiomers, although the marketed form is supplied only as the purified S-enantiomer.
Products: ROPIVACAINE-AFT SOLUTION FOR INJECTION 1% W/V, ROPIVACAINE-AFT SOLUTION FOR INFUSION 0.2% W/V
Drug
Tedizolid phosphate
go.drugbank.com/drugs/DB09042
Approved
This product is currently available as both an oral tablet and as a powder for intravenous injection.[L11232] … [L11232, A199086, A199050] Tedizolid was approved by the FDA on June 20, 2014, for sale by Cubist Pharmaceuticals as tedizolid phosphate (SIVEXTRO®).
Categories: Monoamine Oxidase A Inhibitors for interaction with Monoamine Oxidase A substratesProducts: SIVEXTRO LYOPHILIZED POWDER FOR SOLUTION FOR INFUSION 200MG PER VIAL
Drug
Lipegfilgrastim
go.drugbank.com/drugs/DB13200
Approved
The average molecular mass of lipegfilgrastim comprises 18,798 Da for [DB00099], 203 Da for GalNAc, 338 Da for glycylsialic acid and approximately 20,000 Da for PEG [L2449]. … being treated with cytotoxic chemotherapy for malignancy.
Products: LONQUEX SOLUTION FOR INJECTION IN PRE-FILLED SYRINGE 6MG/0.6ML
Drug
Dobutamine
go.drugbank.com/drugs/DB00841
ApprovedInvestigational
A beta-1 agonist catecholamine that has cardiac stimulant action without evoking vasoconstriction or tachycardia. It is proposed as a cardiotonic after myocardial infarction or open heart surgery.
Categories: Adrenergic alpha-1 Receptor Agonists, Adrenergic beta-1 Receptor AgonistsProducts: DOBUTEL Concentrate for Solution for Infusion 50mg/ml, Pharmaniaga Dobutamine 12.5mg/mL Concentrate for Solution for Infusion
Drug
Palonosetron
go.drugbank.com/drugs/DB00377
ApprovedInvestigational
As of 2008, it is the most recent 5-HT3 antagonist to enter clinical use. … Palonosetron (INN, trade name Aloxi) is an antagonist of 5-HT3 receptors that is indicated for the prevention and treatment of chemotherapy-induced nausea and vomiting (CINV).
Categories: Serotonin Receptor Antagonists, Serotonin 3 Receptor AntagonistsProducts: Solution for Injection 50mcg/ml, ALOXI Solution for Injection 50mcg/ml
Drug
Emicizumab
go.drugbank.com/drugs/DB13923
ApprovedInvestigational
Emicizumab is a humanized recombinant monoclonal antibody that mimics the function of the coagulation Factor VIII and it has the capacity to bind simultaneously to activated Factor IX and Factor X. The ability of Emicizumab to bind to al...
Products: HEMLIBRA 30MG/ML SOLUTION FOR INJECTION, HEMLIBRA 150MG/ML SOLUTION FOR INJECTION
Drug
Cefoperazone
go.drugbank.com/drugs/DB01329
ApprovedInvestigationalWithdrawn
Cefoperazone is a semisynthetic broad-spectrum cephalosporin proposed to be effective against Pseudomonas infections. It is a third-generation antiobiotic agent and it is used in the treatment of various bacterial infections caused by su...
Mixtures: CEFPER 1 g POWDER FOR INJECTION, DUOPERAZONE 1G POWDER FOR INJECTIONCategories: Antibacterials for Systemic Use, Antiinfectives for Systemic Use
Drug
Certolizumab pegol
go.drugbank.com/drugs/DB08904
ApprovedInvestigational
[A176606] It was developed and manufactured by UCB Pharma, first FDA approved in 2008[L45018] and updated for a new indication on March 28, 2019.[L5819] … [A176606] Certolizumab does not require glycosylation for active function and hence, its production is significantly more affordable when compared to other existing TNF-alpha therapies as it can be
Categories: Biologics for Rheumatoid Arthritis Treatment, Tumor Necrosis Factor Receptor Blocking ActivityProducts: CIMZIA 200MG FER, CIMZIA 200 MG ILO IN FER
Drug
Lutetium Lu 177 dotatate
go.drugbank.com/drugs/DB13985
ApprovedInvestigational
It is a first radiopharmaceutical agent to be approved for gastroenteropancreatic neuroendocrine tumors (GEP-NETs) and is indicated for adult patients with somatostatin receptor-positive GEP-NETs [L1191 … Lutetium Lu 177 dotatate was approved by the FDA as Lutathera in January 2018 for intravenous injection.
Products: LUTATHERA SOLUTION FOR INFUSION 370 MBQ/ML
Drug
Romiplostim
go.drugbank.com/drugs/DB05332
ApprovedInvestigational
Romiplostim is a thrombopoiesis stimulating dimer Fc-peptide fusion protein (peptibody) to increase platelet production through activation of the thrombopoietin receptor. … Each subunit consists of an IgG1 Fc carrier domain that is covalently attached to a polypeptide sequence that contains two binding domains to interact with thrombopoietin receptor c-Mpl.
Categories: Thrombopoietin Receptor Agonist, Thrombopoietin Receptor AgonistsProducts: ROMIPLATE POWDER FOR SOLUTION FOR INJECTION 250 ?g/vial