Cefoperazone is a broad-spectrum cephalosporin antibiotic used for the treatment of bacterial infections in various locations, including the respiratory tract, abdomen, skin, and female genital tracts. Cefoperazone is a semisynthetic broad-spectrum cephalosporin proposed to be effective against Pseudomonas infections.
- Mechanism
- Curator reviewed
Like all beta-lactam antibiotics, cefoperazone binds to specific penicillin-binding proteins (PBPs) located inside the bacterial cell wall, causing the inhibition of the third and last stage of bacterial cell wall synthesis. Cell lysis is then mediated by bacterial cell wall autolytic enzymes such as autolysins.
- Primary indication
- Indicated for the treatment of following infections caused by susceptible bacteria: 1) Respiratory tract infections caused by S. pneumoniae, H. influenzae, S. aureus (penicillinase and non-penicillinase producing strains), S. pyogenes (Group A beta-hemolytic streptococci), P....Curator reviewed · 12 structured indications
- Formula / weight
- C25H27N9O8S2 · 645.67 g/mol (avg)
- First approval
- United States, 1982
Resolves to
GCFBRXLSHGKWDP-XCGNWRKASA-NSMILES[H][C@]12SCC(CSC3=NN=NN3C)=C(N1C(=O)[C@@]2([H])NC(=O)[C@H](NC(=O)N1CCN(CC)C(=O)C1=O)C1=CC=C(O)C=C1)C(O)=OWhat you can answer from here — as of September 23, 2026
Which drugs share a target with Cefoperazone, and which of those have an active Phase 3 trial?
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