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Quetiapine
go.drugbank.com/drugs/DB01224ApprovedInvestigationalInitially approved by the FDA in 1997, quetiapine is a second-generation atypical antipsychotic used in schizophrenia, major depression, and bipolar disorder. … [L8546] Quetiapine demonstrates a high level of therapeutic efficacy and low risk of adverse effects during long-term treatment.
Synonyms: 2-[2-(4-Dibenzo[b,f][1,4]thiazepin-11-yl-1-piperazinyl)ethoxy]ethanolMixtures: Quetialan 4 Tage Startpackung - Filmtabletten, Seroquel 4-Tage Startpackung FilmtablettenIron
go.drugbank.com/drugs/DB01592ApprovedInvestigationalA metallic element found in certain minerals, in nearly all soils, and in mineral waters. It is an essential constituent of hemoglobin, cytochrome, and other components of respiratory enzyme systems.
International brands: Ed-In-SolMixtures: FENYSOL-Z 40 MG + 15 MG/5 ML ŞURUP, 100 ML, FERRO SANOL B SURUP, 150 MLFerric carboxymaltose
go.drugbank.com/drugs/DB08917ApprovedInvestigationalIt was FDA approved on July 25, 2013.
Categories: Compounds used in a research, industrial, or household settingProducts: Ferinject® 50 mg iron/mL solution for injection/infusion, Ferapplic 500 mg/10 ml Enjeksiyonluk/İnfüzyonluk Çözelti, 1 flakonTopiramate
go.drugbank.com/drugs/DB00273ApprovedInvestigationalTopiramate is a anti-epileptic drug used to manage seizures and prevent migraines.[A175249] It was initially approved by the FDA in 1996. … [L10550] Characteristics that distinguish topiramate from other antiepileptic drugs are a monosaccharide chemical structure containing a sulfamate, and 40% of its mass accounted for by oxygen.
Synonyms: 2,3:4,5-bis-O-(1-methylethylidene)-β-D-fructopyranose sulfamate, 2,3:4,5-di-O-isopropylidene-β-D-fructopyranose sulfamateCategories: Cytochrome P-450 CYP3A Inducers, Cytochrome P-450 CYP3A4 InducersCisplatin
go.drugbank.com/drugs/DB00515ApprovedInvestigationalCisplatin, cisplatinum or cis-diamminedichloroplatinum(II) (CDDP) is a platinum-based chemotherapy drug used to treat various types of cancers, including sarcomas, some carcinomas (e.g. small cell lung
Categories: Cytochrome P-450 CYP2B6 Inhibitors, Cytochrome P-450 CYP2C9 InhibitorsSynonyms: INT-230-6 COMPONENT CISPLATIN, (SP-4-2)-DIAMMINEDICHLOROPLATINUMKetamine
go.drugbank.com/drugs/DB01221ApprovedInvestigationalVet approvedKetamine is an NMDA receptor antagonist with a potent anesthetic effect.[A31869] It was developed in 1963 as a replacement for phencyclidine (PCP) by Calvin Stevens at Parke Davis Laboratories.
Synonyms: 2-(2-Chloro-phenyl)-2-methylamino-cyclohexanone, 2-(methylamino)-2-(2-chlorophenyl)cyclohexanoneCategories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A InducersEnalapril
go.drugbank.com/drugs/DB00584ApprovedInvestigationalVet approvedIt was developed from a targeted research programmed using molecular modelling. … It is also found in a combination product containing [hydrochlorothiazide] that is used for the management of hypertension.
Synonyms: (S)-1-(N-(1-(ethoxycarbonyl)-3-phenylpropyl)-L-alanyl)-L-proline, 1-(N-((S)-1-carboxy-3-phenylpropyl)-L-alanyl)-L-proline 1'-ethyl esterMixtures: DUOPRES® 5 MG / 20 MG CÁPSULAS, Renitec plus 20 mg/6 mg TablettenAmiodarone
go.drugbank.com/drugs/DB01118ApprovedInvestigationalAmiodarone is a benzofuran derivative, anti-arrhythmic drug used commonly in a variety of settings.
Synonyms: 2-n-Butyl-3',5'-diiodo-4'-N-diethylaminoethoxy-3-benzoylbenzofuran, 2-Butyl-3-(3,5-diiodo-4-(2-diethylaminoethoxy)benzoyl)benzofuranCategories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP1A1 SubstratesIndomethacin
go.drugbank.com/drugs/DB00328ApprovedInvestigationalNSAIDs consist of agents that are structurally unrelated; the NSAID chemical classification of indometacin is an indole-acetic acid derivative with the chemical name 1- (p-chlorobenzoyl)25-methoxy-2-methylindole … -3-acetic acid.
Mixtures: INDOBIOTIC GOZ DAMLASI, 5 MLCategories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP2C9 SubstratesLamotrigine
go.drugbank.com/drugs/DB00555ApprovedInvestigationalIt is used in the treatment of both epilepsy and as a mood stabilizer in bipolar disorder. … Lamotrigine is the first medication since lithium granted Food and Drug Administration (FDA) approval for the maintenance treatment of bipolar type I. It is approved for use in more than 30 countries.
Categories: P-glycoprotein inhibitors, P-glycoprotein substratesSynonyms: 3,5-diamino-6-(2,3-dichlorophenyl)-1,2,4-triazine