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Pictilisib
go.drugbank.com/drugs/DB11663InvestigationalPictilisib has been used in trials studying the treatment of Solid Cancers, Breast Cancer, Advanced Solid Tumours, Metastatic Breast Cancer, and Non-Hodgkin's Lymphoma, Solid Cancers, among others.
Fazpilodemab
go.drugbank.com/drugs/DB18924InvestigationalFazpilodemab is under investigation in clinical trial NCT04171765 (A Study to Evaluate the Efficacy, Safety, and Pharmacokinetics of BFKB8488A Compared With Placebo in Participants With Non-alcoholic Steatohepatitis
Gamolenic acid
go.drugbank.com/drugs/DB13854ApprovedWithdrawnGamolenic acid, or gamma-linolenic acid (γ-Linolenic acid) or GLA, is an essential fatty acid (EFA) comprised of 18 carbon atoms with three double bonds that is most commonly found in human milk and other botanical sources . It is an ome...
Hyoscyamine
go.drugbank.com/drugs/DB00424ApprovedInvestigationalHyoscyamine is a tropane alkaloid and the levo-isomer of atropine. It is commonly extracted from plants in the Solanaceae or nightshade family. Research into the action of hyoscyamine in published literature dates back to 1826. Hyoscyami...
Enlicitide
go.drugbank.com/drugs/DB22580ApprovedInvestigationalPCSK9 binds low-density lipoprotein receptors (LDLR) on the surface of hepatocytes and promotes their degradation within the liver; by blocking this interaction, enlicitide increases the number of LDLRs … 56% relative to placebo in patients with hypercholesterolemia at established or increased ASCVD risk (CORALreef Lipids), and by 59% in patients with HeFH (CORALreef HeFH), with comparable reductions in non-HDL-C
Gadoversetamide
go.drugbank.com/drugs/DB00538ApprovedGadoversetamide, marketed under the trade name OptiMARK, is a gadolinium compound used as a contrast agent in magnetic resonance imaging (MRI), particularly imaging of the brain, spine and liver.
Polydatin
go.drugbank.com/drugs/DB11263ApprovedIt is shown to mediate a cytotoxic action on colorectal cancer cells by inducing cell arrest and apoptosis [A27229].
Technetium Tc-99m tetrofosmin
go.drugbank.com/drugs/DB09160Approved[A31592] Technetium Tc-99m tetrofosmin was developed by GE Healthcare and FDA approved on February 9, 1996.
Ioxaglic acid
go.drugbank.com/drugs/DB09313ApprovedWithdrawnLike other organic iodine compounds, ioxaglic acid blocks x-rays and is opaque in its appearance on x-ray film, improving the visualization of important structures and organs during angiography, arteriography
Rosin
go.drugbank.com/drugs/DB11165ApprovedRosin has shown to mediate antibacterial actions on Gram-positive bacterial species [A27267].