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Displaying results 2591 - 2600 of 10000 in total
  1. Drug

    PIK-75

    go.drugbank.com/drugs/DB17047
    Experimental

    PIK-75 is a preferential p110 alpha/gamma PI3K inhibitor.[A253097]

    Categories: Phosphatidylinositol 3-Kinases, antagonists & inhibitorsSynonyms: Benzenesulfonic acid, 2-methyl-5-nitro-, 2-((6-bromoimidazo(1,2-a)pyridin-3-yl)methylene)-1-methylhydrazide
  2. Drug

    PD173955

    go.drugbank.com/drugs/DB02567
    Experimental

    Synonyms: 6-(2,6-dichlorophenyl)-8-methyl-2-{[3-(methylthio)phenyl]amino}pyrido[2,3-d]pyrimidin-7(8H)-oneCategories: Heterocyclic Compounds, 1-Ring
  3. Drug

    Depulfavirine

    go.drugbank.com/drugs/DB18890
    Investigational

    Depulfavirine is under investigation in clinical trial NCT05204394 (Study to Evaluate Efficacy and Safety of Switching to VM-1500A-LAI + 2nrtis From the 1st Line Standard of Care Therapy).

    Synonyms: 2-[4-Bromo-3-(3-chloro-5-cyanophenoxy)-2-fluorophenyl]-N-(2-chloro-4-sulfamoylphenyl)acetamide, Benzeneacetamide, N-[4-(aminosulfonyl)-2-chlorophenyl]-4-bromo-3-(3-chloro-5-cyanophenoxy)-2-fluoro-
  4. Drug

    NRC-AN-019

    go.drugbank.com/drugs/DB17110
    Experimental

    Synonyms: (3,5-BIS TRIFLUOROMETHYL)-N-(4-METHYL-3-(4-PYRIDIN-3YL-PYRIMIDIN-2-YL AMINO) PHENYL)BENZAMIDE, 3,5-BIS(TRIFLUOROMETHYL)-N-(4-METHYL-3-((4-(PYRIDIN-3-YL)PYRIMIDIN-2-YL)AMINO)PHENYL)BENZAMIDECategories: Heterocyclic Compounds, 1-Ring
  5. Drug

    Cabazitaxel

    go.drugbank.com/drugs/DB06772
    ApprovedInvestigational

    Cabazitaxel is a taxoid synthesized from 10-deacetylbaccatin III, a compound isolated from the yew tree. … [A7056] Due to its low affinity for the P-glycoprotein (P-gp) efflux pump, cabazitaxel can more readily penetrate the blood–brain barrier compared to other taxanes like [paclitaxel] and [docetaxel].

    Categories: P-glycoprotein substrates with a Narrow Therapeutic Index, Cytochrome P-450 CYP2C8 Substrates with a Narrow Therapeutic IndexSynonyms: 1-HYDROXY-7.BETA.,10.BETA.-DIMETHOXY-9-OXO-5.BETA.,20-EPOXYTAX-11-ENE-2.ALPHA.,4,13.ALPHA.-TRIYL 4-ACETATE 2-BENZOATE 13-((2R,3S)-3-(((TERT-BUTOXY)CARBONYL)AMINO)-2-HYDROXY-3-PHENYLPROPANOATE)
  6. Drug

    Romilkimab

    go.drugbank.com/drugs/DB16318
    Investigational

    Romilkimab is under investigation in clinical trial NCT02345070 (Efficacy and Safety of SAR156597 in the Treatment of Idiopathic Pulmonary Fibrosis).

    Synonyms: Bispecific antibody targeting interleukin 4 (IL-4) and interleukin 13 (IL-13)
  7. Drug

    Acridine Carboxamide

    go.drugbank.com/drugs/DB11880
    Investigational

    Acridine Carboxamide has been used in trials studying the treatment of Lung Cancer and Brain and Central Nervous System Tumors.

    Categories: Heterocyclic Compounds, 3-RingSynonyms: 4-ACRIDINECARBOXAMIDE, N-(2-(DIMETHYLAMINO)ETHYL)-, N-(2-(DIMETHYLAMINO)ETHYL)ACRIDINE-4-CARBOXAMIDE
  8. Drug

    DMP-777

    go.drugbank.com/drugs/DB18488
    Experimental

    DMP-777 is a selective inhibitor of polymorphonuclear leukocyte (PMN) elastase.

    Categories: Heterocyclic Compounds, 1-RingSynonyms: 1-AZETIDINECARBOXAMIDE, N-((1R)-1-(1,3-BENZODIOXOL-5-YL)BUTYL)-3,3-DIETHYL-2-(4-((4-METHYL-1-PIPERAZINYL)CARBONYL)PHENOXY)-4-OXO-, (2S)-
  9. Drug

    AGS-499

    go.drugbank.com/drugs/DB18058
    Experimental

    Synonyms: Phenol, 4,4′,4′′-ethylidynetris[2,6-diethoxy-, 4,4',4''-(Ethane-1,1,1- triyl)tris(2,6-diethoxyphenol)
  10. Drug

    Parapropamol

    go.drugbank.com/drugs/DB20800
    Experimental

    Parapropamol is a small molecule drug. Parapropamol has a monoisotopic molecular weight of 165.08 Da.

    Synonyms: N-propionyl-4-aminophenol, 4'-hydroxypropionanilid