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Depulfavirine

This drug entry is a stub and has not been fully annotated. It is scheduled to be annotated soon.

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Data Packages
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Identification

Generic Name
Depulfavirine
DrugBank Accession Number
DB18890
Background

Depulfavirine is under investigation in clinical trial NCT05204394 (Study to Evaluate Efficacy and Safety of Switching to VM-1500A-LAI + 2nrtis From the 1st Line Standard of Care Therapy).

Type
Small Molecule
Groups
Investigational
Structure
3D
Similar Structures
Weight
Average: 573.21
Monoisotopic: 570.917124
Chemical Formula
C21H13BrCl2FN3O4S
Synonyms
  • 2-[4-Bromo-3-(3-chloro-5-cyanophenoxy)-2-fluorophenyl]-N-(2-chloro-4-sulfamoylphenyl)acetamide
  • Benzeneacetamide, N-[4-(aminosulfonyl)-2-chlorophenyl]-4-bromo-3-(3-chloro-5-cyanophenoxy)-2-fluoro-
  • Depulfavirine
External IDs
  • RO 4970335
  • RO-0335
  • RO-4970335
  • RO0335
  • RO4970335
  • VM 1500A
  • VM-1500A
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Pharmacology

Indication

Not Available

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Contraindications & Blackbox Warnings
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Pharmacodynamics

Not Available

Mechanism of action
Not Available
Absorption

Not Available

Volume of distribution

Not Available

Protein binding

Not Available

Metabolism
Not Available
Route of elimination

Not Available

Half-life

Not Available

Clearance

Not Available

Adverse Effects
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Toxicity

Not Available

Pathways
Not Available
Pharmacogenomic Effects/ADRs
Not Available

Interactions

Drug Interactions
This information should not be interpreted without the help of a healthcare provider. If you believe you are experiencing an interaction, contact a healthcare provider immediately. The absence of an interaction does not necessarily mean no interactions exist.
Not Available
Food Interactions
Not Available

Categories

Drug Categories
Not Available
Classification
Not classified
Affected organisms
Not Available

Chemical Identifiers

UNII
ZP6H7RDZ5Q
CAS number
867365-76-2
InChI Key
SBUUICLVCQQMFP-UHFFFAOYSA-N
InChI
InChI=1S/C21H13BrCl2FN3O4S/c22-16-3-1-12(20(25)21(16)32-14-6-11(10-26)5-13(23)8-14)7-19(29)28-18-4-2-15(9-17(18)24)33(27,30)31/h1-6,8-9H,7H2,(H,28,29)(H2,27,30,31)
IUPAC Name
SMILES
NS(=O)(=O)C1=CC=C(NC(=O)CC2=CC=C(Br)C(OC3=CC(Cl)=CC(=C3)C#N)=C2F)C(Cl)=C1

References

General References
Not Available
ChemSpider
9774245
ChEMBL
CHEMBL4438269
ZINC
ZINC000043172139
PDBe Ligand
VM5

Clinical Trials

Clinical Trials
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PhaseStatusPurposeConditionsCountStart DateWhy Stopped100+ additional columns
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2, 3Not Yet RecruitingTreatmentHuman Immunodeficiency Virus Type 1 (HIV-1) Infection1somestatusstop reasonjust information to hide
1CompletedTreatmentHuman Immunodeficiency Virus Type 1 (HIV-1) Infection1somestatusstop reasonjust information to hide
1, 2CompletedTreatmentHuman Immunodeficiency Virus Type 1 (HIV-1) Infection1somestatusstop reasonjust information to hide

Pharmacoeconomics

Manufacturers
Not Available
Packagers
Not Available
Dosage Forms
Not Available
Prices
Not Available
Patents
Not Available

Properties

State
Not Available
Experimental Properties
Not Available
Predicted Properties
PropertyValueSource
Predicted ADMET Features
Not Available

Spectra

Mass Spec (NIST)
Not Available
Spectra
Not Available
Chromatographic Properties
Collision Cross Sections (CCS)
Not Available

Drug created at June 27, 2024 03:02 / Updated at June 28, 2024 04:46