Depulfavirine

DB18890InvestigationalSmall molecule

Depulfavirine is under investigation in clinical trial NCT05204394 (Study to Evaluate Efficacy and Safety of Switching to VM-1500A-LAI + 2nrtis From the 1st Line Standard of Care Therapy).

Chemical structure of Depulfavirine
Formula / weight
C21H13BrCl2FN3O4S · 573.21 g/mol (avg)
Also known as
2-[4-Bromo-3-(3-chloro-5-cyanophenoxy)-2-fluorophenyl]-N-(2-chloro-4-sulfamoylphenyl)acetamide · Benzeneacetamide, N-[4-(aminosulfonyl)-2-chlorophenyl]-4-bromo-3-(3-chloro-5-cyanophenoxy)-2-fluoro-
Code names
RO-0335 · RO-4970335 · VM-1500A

Resolves to

Compound
UNIIZP6H7RDZ5QCAS867365-76-2ChEMBLCHEMBL4438269
Structure
InChIKeySBUUICLVCQQMFP-UHFFFAOYSA-NSMILESNS(=O)(=O)C1=CC=C(NC(=O)CC2=CC=C(Br)C(OC3=CC(Cl)=CC(=C3)C#N)=C2F)C(Cl)=C1
Targets
O14746TERT

What you can answer from here — as of February 04, 2025

1Protein targetEach mapped to UniProt, with action and pharmacological action
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2Clinical trialsPhase, status and sponsor resolved per trial
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1+ReferenceStructured and connected to the statements they support
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