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Mavorixafor
go.drugbank.com/drugs/DB05501ApprovedInvestigationalMavorixafor is a CXC chemokine receptor 4 (CXCR4) antagonist. … by a reduced number of mature neutrophils and lymphocytes.
Categories: MATE 1 Inhibitors, P-glycoprotein inhibitorsSynonyms: 1,4-BUTANEDIAMINE, N-(1H-BENZIMIDAZOL-2-YLMETHYL)-N-((8S)-5,6,7,8-TETRAHYDRO-8-QUINOLINYL)-, N1-(1H-BENZIMIDAZOL-2-YLMETHYL)-N1-((S)-5,6,7,8-TETRAHYDROQUINOLIN-8-YL)-BUTANE-1,4-DIAMINENM-702
go.drugbank.com/drugs/DB05505InvestigationalIn the USA, a Phase 2 study for intermittent claudication caused by arteriosclerosis obliterans has been successfully completed. … Intermittent claudication is a major symptom of arteriosclerosis obliterans.
Categories: Heterocyclic Compounds, 1-RingBelnacasan
go.drugbank.com/drugs/DB05507InvestigationalVX-765 is the orally available prodrug of a potent and selective competitive inhibitor of ICE/caspase-1 (VRT-043198).
Piclidenoson
go.drugbank.com/drugs/DB05511InvestigationalCF 101 (known generically as IB-MECA) is an anti-inflammatory drug for rheumatoid arthritis patients. Its novel mechanism of action relies on antagonism of adenoside A3 receptors. CF101 is supplied as an oral drug and has an excellent sa...
Categories: Heterocyclic Compounds, 2-RingMimopezil
go.drugbank.com/drugs/DB05520ExperimentalMimopezil is a pro-drug that is rapidly absorbed and converted into huperzine A.
Synonyms: N-(2-Hydroxy-3-methoxy-5-chlorobenzylidene)huperzine AQR-333
go.drugbank.com/drugs/DB05533InvestigationalQR-333 is a concentrated and standardized nutrient based active compounds dosed in a topical cream designed to reduce oxidative stress and treat symptoms of Diabetic Peripheral Neuropathy, a nerve disorder … QR-333 has been investigated as a treatment for diabetic peripheral neuropathy.
AMG 108
go.drugbank.com/drugs/DB05545InvestigationalAMG 108 was investigated for use as an antirheumatic agent.
Categories: Interleukin-1 Receptor Antagonist, Receptors, Interleukin-1, antagonists & inhibitorsSB-743921
go.drugbank.com/drugs/DB05546InvestigationalCategories: Heterocyclic Compounds, 1-Ring, Heterocyclic Compounds, 2-RingEnokizumab
go.drugbank.com/drugs/DB05555InvestigationalA humanized immunoglobulin G1k anti-interleukin-9 mAb.
Delcasertib
go.drugbank.com/drugs/DB05560InvestigationalCategories: Protein Kinase C-delta, antagonists & inhibitors