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Displaying results 2621 - 2630 of 2828 in total
  1. Drug

    Alaproclate

    go.drugbank.com/drugs/DB13233
    Experimental

    Alaproclate was developed as one of the first selective serotonin reuptake inhibitor (SSRI) antidepressants by Astra AB (now AstraZeneca) in the 1970s. Development was discontinued due to concerns over hepatotoxicity observed in animal s...

    Categories: Membrane Transport Modulators
  2. Drug

    Bencyclane

    go.drugbank.com/drugs/DB13488
    Experimental

    A vasodilator agent found to be effective in a variety of peripheral circulation disorders. It has various other potentially useful pharmacological effects. Its mechanism may involve block of calcium channels.

    Categories: Membrane Transport Modulators
  3. Drug

    Mivebresib

    go.drugbank.com/drugs/DB21300
    Investigational

    The usage of the INN stem '-bresib' in the name indicates that Mivebresib is a inhibitor of the bromodomain and extra-terminal motif (BET) family of bromodomain (BRD) protein, antineoplastic.

  4. Drug

    Linaprazan glurate

    go.drugbank.com/drugs/DB21534
    Investigational

    The usage of the INN stem '-prazan' in the name indicates that Linaprazan glurate is a proton pump inhibitor, not dependent on acid activation.

  5. Drug

    Olodaterol

    go.drugbank.com/drugs/DB09080
    ApprovedInvestigational

    Single doses of olodaterol have been shown to improve forced expiratory volume in 1 sec (FEV1) for 24 h in patients with COPD, allowing once daily dosing.

  6. Drug

    Gallopamil

    go.drugbank.com/drugs/DB12923
    Investigational

    Gallopamil has been used in trials studying the treatment of Asthma.

    Categories: Membrane Transport Modulators
  7. Drug

    Pentamycin

    go.drugbank.com/drugs/DB13571
    Experimental

    Categories: Genito Urinary System and Sex Hormones
  8. Drug

    Demegestone

    go.drugbank.com/drugs/DB13857
    Experimental

    Demegestone is a progesterone receptor agonist that was previously used to treat luteal insufficiency. It was previously marketed in France as Lutionex, but has since been discontinued.

    Categories: Genito Urinary System and Sex Hormones, Sex Hormones and Modulators of the Genital System
  9. Drug

    Faricimab

    go.drugbank.com/drugs/DB15303
    ApprovedInvestigational

    However, another set of factors, the Tie/Ang axis, comprising the transmembrane Tie-2 receptor and its soluble ligands Ang-1 and Ang-2, has been shown to play critical roles in mediating VEGF-A-induced

  10. Drug

    FT516

    go.drugbank.com/drugs/DB15732
    Investigational

    FT516 is an investigational and engineered off-the-shelf natural killer (NK) cell therapy originating from induced pluripotent stem cells (iPSC).