Demegestone

DB13857ExperimentalSmall molecule

Demegestone is a progesterone receptor agonist that was previously used to treat luteal insufficiency. It was previously marketed in France as Lutionex, but has since been discontinued.

Chemical structure of Demegestone
Mechanism
Curator reviewed
Formula / weight
C21H28O2 · 312.4458 g/mol (avg)
Code names
R 2453

Resolves to

Clinical / RWD
Structure
InChIKeyJWAHBTQSSMYISL-MHTWAQMVSA-NSMILES[H][C@@]12CC[C@](C)(C(C)=O)[C@@]1(C)CCC1=C3CCC(=O)C=C3CC[C@@]21[H]
Targets

What you can answer from here — as of February 21, 2021

1Protein targetEach mapped to UniProt, with action and pharmacological action
Listed above
544Drug interactionsStructured to mechanism, not free text
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1ATC codeIncluding every combination product, plus 18 drug categories
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2+ReferencesStructured and connected to the statements they support
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Which drugs share a target with Demegestone, and which of those have an active Phase 3 trial?

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