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Tildacerfont
go.drugbank.com/drugs/DB18545InvestigationalTildacerfont is a corticotropin-releasing factor receptor-1 antagonist containing an unfused thiazole ring
Synonyms: 3-(5-chloro-2-morpholin-4-yl-thiazol-4-yl)-7-(1-ethyl-propyl)-2,5-dimethyl-pyrazolo(1,5-a)pyrimidine, Pyrazolo(1,5-a)pyrimidine, 3-(4-chloro-2-(4-morpholinyl)-5-thiazolyl)-7-(1-ethylpropyl)-2,5-dimethyl-GSBR-1290
go.drugbank.com/drugs/DB18551InvestigationalGSBR-1290 is a small molecule agonist of the GLP-1 receptor.
QXL138AM
go.drugbank.com/drugs/DB18552InvestigationalQXL138AM is a masked immunocytokine (MIC) comprised of an anti-CD138 immunoglobulin G1 antibody fused to interferon alpha 2a. It binds the CD138 protein on the surface of the tumour cells.
mRNA-3745
go.drugbank.com/drugs/DB18554InvestigationalmRNA-3745 is a lipid nanoparticle (LNP) encapsulated with nucleoside-modified, codon-optimized mRNAs encoding human glucose 6-phosphatase (G6Pase).
Ergidina
go.drugbank.com/drugs/DB18565ExperimentalErgidina is a recombinant human minibody against complement component C5 fused with RGD-motif.
Synonyms: Neutralizing scFv dimer to C5 fused at the C terminal end to the Fc domains of human IgG1 and the cyclic RGD-4C peptide (ACDCRGDCFCG)PBGM01
go.drugbank.com/drugs/DB18581InvestigationalPBGM01 is a non-replicating recombinant adeno-associated virus serotype hu68 vector, which contains human GLB1 transgene encoding the galactosidase beta 1 enzyme.
CTR-107
go.drugbank.com/drugs/DB18583ExperimentalCTR-107 is a synthetic targeted growth factor. It is being investigated for the treatment of familial exudative vitreoretinopathy.
Zelpultide alfa
go.drugbank.com/drugs/DB18587InvestigationalZelpultide alfa is a recombinant human surfactant protein D.
Synonyms: RECOMBINANT SP-D, HUMAN PULMONARY SURFACTANT-ASSOCIATED PROTEIN D (PSPD, SURFACTANT PROTEIN D, SP-D, COLLECTIN-7, SURFACTANT PROTEIN D), NON-COVALENT QUADRUPLE TRIMER, PRODUCED IN HUMAN MYELOGENOUS LEUKEMIA K562 CELLS,2G7
go.drugbank.com/drugs/DB18589Experimental2G7 is an anti-TGF-beta monoclonal antibody developed by Genentech.
Synonyms: Recombinant humanized anti-transforming growth factor (TGF) beta 3 antibody