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Displaying results 2631 - 2640 of 10000 in total
  1. Drug

    Cedazuridine

    go.drugbank.com/drugs/DB15694
    ApprovedInvestigational

    [A215082, A215092, A215097] Hypomethylating agents such as [decitabine] and [azacitidine] are used to treat MDS through inducing DNA hypomethylation and apoptosis of cancerous cells. … Myelodysplastic syndromes (MDS) are a group of hematopoietic neoplasms that give rise to variable cytopenias progressing to secondary acute myeloid leukemia (sAML), which is invariably fatal if untreated

  2. Drug

    Remoxipride

    go.drugbank.com/drugs/DB00409
    ApprovedWithdrawn

    Remoxipride is an atypical antipsychotic agent that is specific for dopamine D<sub>2</sub> receptors. … [A215422] It gained approval in the UK in 1989 but was withdrawn in 1993 after it was found to be associated with an increased incidence of aplastic anemia.[A215422,A215512]

  3. Drug

    Brigatinib

    go.drugbank.com/drugs/DB12267
    ApprovedInvestigational

    Brigatinib, originally named AP26113, is a reversible dual inhibitor of anaplastic lymphoma kinase (ALK) and epidermal growth factor receptor (EGFR). … It presents selectivity against the mutant forms of EGFR compared to the wild-type.

  4. Drug

    Betoxycaine

    go.drugbank.com/drugs/DB19475
    Experimental

    Betoxycaine is a small molecule drug. The usage of the INN stem '-caine' in the name indicates that Betoxycaine is a local anaesthetic. Betoxycaine has a monoisotopic molecular weight of 352.24 Da.

  5. Drug

    Motrazepam

    go.drugbank.com/drugs/DB19799
    Experimental

    Motrazepam is a small molecule drug. The usage of the INN stem '-azepam' in the name indicates that Motrazepam is a diazepam derivative. Motrazepam has a monoisotopic molecular weight of 325.11 Da.

  6. Drug

    Oximonam

    go.drugbank.com/drugs/DB19915
    Experimental

    Oximonam is a small molecule drug. The usage of the INN stem '-monam' in the name indicates that Oximonam is a monobactam antibiotic. Oximonam has a monoisotopic molecular weight of 357.07 Da.

  7. Drug

    Oxazafone

    go.drugbank.com/drugs/DB19954
    Experimental

    Oxazafone is a small molecule drug. The usage of the INN stem '-zafone' in the name indicates that Oxazafone is a alozafone derivative. Oxazafone has a monoisotopic molecular weight of 360.12 Da.

  8. Drug

    Ditekiren

    go.drugbank.com/drugs/DB19992
    Experimental

    Ditekiren is a small molecule drug. The usage of the INN stem '-kiren' in the name indicates that Ditekiren is a renin inhibitor. Ditekiren has a monoisotopic molecular weight of 929.57 Da.

  9. Drug

    Fexicaine

    go.drugbank.com/drugs/DB20038
    Experimental

    Fexicaine is a small molecule drug. The usage of the INN stem '-caine' in the name indicates that Fexicaine is a local anaesthetic. Fexicaine has a monoisotopic molecular weight of 426.25 Da.

  10. Drug

    Prazepine

    go.drugbank.com/drugs/DB20174
    Experimental

    Prazepine is a small molecule drug. The usage of the INN stem '-zepine' in the name indicates that Prazepine is a tricyclic compound. Prazepine has a monoisotopic molecular weight of 280.19 Da.