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Avoplacel
go.drugbank.com/drugs/DB18659InvestigationalAvoplacel (PLX-R18) is an allogeneic cell therapy under investigation for the treatment of acute radiation syndrome.[L48370]
Ex vivo expanded autologous human corneal epithelial cells containing stem cells
go.drugbank.com/drugs/DB18660ApprovedWithdrawnHoloclar (_ex vivo_ expanded autologous human corneal epithelial cells containing stem cells) is a stem cell therapy used to treat limbal stem cell deficiencies.[L48375]
Rugonersen
go.drugbank.com/drugs/DB18662InvestigationalRugonersen is a locked nucleic acid antisense oligonucleotide under investigation for the treatment of Angelman Syndrome.
AMP-201
go.drugbank.com/drugs/DB18663ExperimentalAMP-201 comprises an adeno-associated virus type 8 vector (AAV8) encoding the collagen Q gene (COLQ). It is under investigation for the treatment of collagen Q congenital myasthenia.
Synonyms: Adeno Associated Virus Serotype 8 Encoding the Collagen Q GenePsoralen
go.drugbank.com/drugs/DB18665InvestigationalSynonyms: 6-hydroxy-5-benzofuranacrylic acid .delta.-lactoneCategories: Monoamine Oxidase A Inhibitors for interaction with Monoamine Oxidase A substrates, Heterocyclic Compounds, 1-RingDNL343
go.drugbank.com/drugs/DB18678InvestigationalDNL343 is under investigation in clinical trial NCT05842941 (HEALEY ALS Platform Trial - Regimen G DNL343).
Cellspan Esophageal Implant
go.drugbank.com/drugs/DB18688ExperimentalThe Cellspan Esophageal ImplantTM (CEI) composes of autologous adipose-derived mesenchymal stromal cells (Ad-MSC) seeded onto a polyurethane tubular mesh cell delivery device.
inBreath airway transplant system
go.drugbank.com/drugs/DB18692ExperimentalinBreath airway transplant system composes of a scaffold seeded with autologous bone marrow cells and incubated in the bioreactor for two days prior to implant.
Metelimumab
go.drugbank.com/drugs/DB18695ExperimentalMetelimumab (CAT-192) is a monoclonal antibody targeted against transforming growth factor (TGF) beta-1.
Synonyms: Human anti-transforming growth factor beta 1 monoclonal antibody, Immunoglobulin g4, anti-(human transforming growth factor .beta.1 (human monoclonal cat-192 .gamma.4-chain)), disulfide with human monoclonal cat-192 .kappa.-chain, dimer