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Cardiolipin Biosynthesis CL(a-15:0/i-22:0/a-25:0/a-25:0)
smpdb.ca/view/SMP0490176MetabolicCardiolipin (CL) is an important component of the inner mitochondrial membrane where it constitutes about 20% of the total lipid composition. It is essential for the optimal function of numerous enzymes that are involved in mitochondrial...
Cardiolipin Biosynthesis CL(i-14:0/i-22:0/a-25:0/a-25:0)
smpdb.ca/view/SMP0491748MetabolicCardiolipin (CL) is an important component of the inner mitochondrial membrane where it constitutes about 20% of the total lipid composition. It is essential for the optimal function of numerous enzymes that are involved in mitochondrial...
Cardiolipin Biosynthesis CL(i-15:0/i-24:0/a-25:0/a-25:0)
smpdb.ca/view/SMP0495475MetabolicCardiolipin (CL) is an important component of the inner mitochondrial membrane where it constitutes about 20% of the total lipid composition. It is essential for the optimal function of numerous enzymes that are involved in mitochondrial...
Trametinib
go.drugbank.com/drugs/DB08911ApprovedInvestigational[A258298] It was later approved by Health Canada on July 18, 2013 [L45588] and by the European Commission on June 30, 2014. … Trametinib is an orally bioavailable mitogen-activated extracellular signal-regulated kinase 1 (MEK1) and MEK2 inhibitor.
Categories: Heterocyclic Compounds, 2-Ring, MAP Kinase Kinase 2, antagonists & inhibitorsProducts: MEKINIST 2 MG FILM KAPLI TABLET ,7 TABLET, MEKINIST 0.5 MG FILM KAPLI TABLET ,7 TABLETValethamate
go.drugbank.com/drugs/DB13497InvestigationalMixtures: EPIDOSIN COMPOSITUM ÇOCUKLARA, 5 ADET, EPIDOSIN COMPOSITUM 10 MG AMPUL, 3 ADETProducts: EPIDOSIN 8 MG/8 ML AMPUL, 5 ADET, EPIMOL 8 MG/ML IM/IV ENJEKSIYONLUK COZELTI, 5 AMPULMiglustat
go.drugbank.com/drugs/DB00419ApprovedInvestigationalIt has recently been approved for treatment of progressive neurological symptoms in adult and pediatric patients in the European Union, Brazil, and South Korea. … However, clinical experience with miglustat showed that therapeutic levels of the drug could not be achieved in patients without a high incidence of adverse effect.
Synonyms: N-(n-Butyl)deoxynojirimycin, N-butyl-1-deoxynojirimycinCategories: Heterocyclic Compounds, 1-RingPinaverium
go.drugbank.com/drugs/DB09090ApprovedInvestigationalPinaverium is a spasmolytic agent used for functional gastrointestinal disorders. It is a quaternary ammonium compound that acts as an atypical calcium antagonist to restore normal bowel function. … Although it is not a currently approved drug by the FDA, pinaverium is available in over 60 countries including Canada.
Mixtures: BROMUX D® 100/300 MG CÁPSULA., DUOTRYNE®Categories: Cytochrome P-450 Substrates, Heterocyclic Compounds, 1-RingCarfilzomib
go.drugbank.com/drugs/DB08889ApprovedInvestigationalCarfilzomib is an injectable antineoplastic agent (IV only). Chemically, it is a modified tetrapeptidyl epoxide and an analog of epoxomicin. It is also a selective proteasome inhibitor. … FDA approved carfilzomib in July 2012 for the treatment of adults with relapsed or refractory multiple myeloma as monotherapy or combination therapy.[L39392]
Categories: P-glycoprotein substrates with a Narrow Therapeutic Index, P-glycoprotein inhibitorsProducts: ANPROTSOM ® 60 MG, Kyprolis 10 mg IV İnfüzyonluk Çözelti Hazırlamak İçin Toz, 1 ADETEliglustat
go.drugbank.com/drugs/DB09039ApprovedInvestigational[L41404,A7634] Eliglustat was approved by the FDA in August 2014 as an oral substrate reduction therapy for the first-line treatment of type 1 Gaucher disease. … [A3752,L41404] Gaucher disease is a rare genetic disorder characterized by the deficiency of acid β-glucosidase, an enzyme that converts glucosylceramide into glucose and ceramide.
Synonyms: N-[(1R,2R)-1-(2,3-Dihydro-1,4-benzodioxin-6-yl)-1-hydroxy-3-(1-pyrrolidinyl)-2-propanyl]octanamideCategories: P-glycoprotein inhibitors, Cytochrome P-450 SubstratesCardiolipin Biosynthesis CL(a-13:0/a-25:0/18:2(9Z,11Z)/a-25:0)
smpdb.ca/view/SMP0044939DiseaseCardiolipin (CL) is an important component of the inner mitochondrial membrane where it constitutes about 20% of the total lipid composition. It is essential for the optimal function of numerous enzymes that are involved in mitochondrial...