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Displaying results 2681 - 2690 of 10000 in total
  1. Drug

    Interferon alfa-2a

    go.drugbank.com/drugs/DB00034
    ApprovedInvestigationalWithdrawn

    Interferon a (human leukocyte protein moiety reduced). A type I interferon consisting of 165 amino acid residues with lysine in position 23. … It is used extensively as an antiviral or antineoplastic agent. An oral form is being developed by Amarillo Biosciences.

    Synonyms: Interferon Alfa 2A, Interferon alfa-2aInternational brands: Roferon A
  2. Drug

    Human papillomavirus type 18 L1 capsid protein residues 2-472 antigen

    go.drugbank.com/drugs/DB10995
    ApprovedWithdrawn

    Mixtures: CERVARIX SUSPENSION FOR INJECTIONSynonyms: Human papillomavirus type 18 L1 capsid protein residues 2-472 antigen
  3. Drug

    Prednisone

    go.drugbank.com/drugs/DB00635
    ApprovedInvestigationalVet approved

    A synthetic anti-inflammatory glucocorticoid derived from [cortisone].[A187463] It is biologically inert and converted to [prednisolone] in the liver.

    Categories: Corticosteroids for Systemic Use, Corticosteroids for Systemic Use, Plain
  4. Drug

    Obinutuzumab

    go.drugbank.com/drugs/DB08935
    ApprovedInvestigational

    This chemical modification significantly enhances its affinity for FcγRIII receptors on immune effector cells. … [A274641] As a result, obinutuzumab induces greater antibody-dependent cellular cytotoxicity (ADCC) and a higher degree of direct cell death compared to rituximab.

    Products: GAZYVA 1000 MG/ 40 ML CONCENTRATE FOR SOLUTION FOR INFUSION, GAZYVA CONCENTRATE FOR SOLUTION FOR INFUSION 1000MG/40ML
  5. Drug

    Dithiazanine

    go.drugbank.com/drugs/DB11516
    ApprovedVet approvedWithdrawn

    Dithiazanine is a highly potent anthelmintic, introduced in 1959 for the treatment of strongyloid worms and whipworms. However, its use is severely limited due to its toxicity.

    Categories: Compounds used in a research, industrial, or household setting
  6. Drug

    Polythiazide

    go.drugbank.com/drugs/DB01324
    Approved

    A thiazide diuretic with actions and uses similar to those of hydrochlorothiazide. (From Martindale, The Extra Pharmacopoeia, 30th ed, p826)

    Categories: Antihypertensive Agents Indicated for Hypertension
  7. Drug

    Enpatoran

    go.drugbank.com/drugs/DB16501
    Investigational

    Additionally, M5049 was studied for COVID-19 pneumonia in a completed trial with results (NCT04448756) and is currently being recruited for a trial involving participants with dermatomyositis and polymyositis … It was investigated for systemic lupus erythematosus and cutaneous lupus erythematosus in completed trials (NCT04647708 and NCT05162586) and in a recruiting trial (NCT05540327).

    Categories: Experimental Unapproved Treatments for COVID-19
  8. Drug

    Exagamglogene autotemcel

    go.drugbank.com/drugs/DB15572
    ApprovedInvestigational

    Sickle cell disease (SCD) is a genetic disorder characterized by the production of abnormal sickle-shaped red blood cells (called hemoglobin S, HbS) that initiate a pathophysiology resulting in severe … ] - a mainstay of treatment since the 1990s - as well as newer agents like [crizanlizumab] and [voxelotor].

    Synonyms: from mobilised peripheral blood by positive selection, modified by CRISPR/Cas9 (clustered regularly interspaced short palindromic repeats/CRISPR-associated protein 9) mediated gene editing consisting of a
  9. Drug

    ANA971

    go.drugbank.com/drugs/DB05127
    Experimental

    Isatoribine is a nucleoside analog in development for the treatment of chronic hepatitis C virus (HCV) infection. ANA971 is a prodrug designed to improve the oral bioavailability of isatoribine.

  10. Drug

    Trichophyton mentagrophytes

    go.drugbank.com/drugs/DB10446
    Approved

    Trichophyton mentagrophytes is a fungus which can provoke allergic reactions. Trichophyton mentagrophytes extract is used in allergenic testing.

    Mixtures: Trichophyton for Intradermal Skin Testing